التفاصيل البيبلوغرافية
| العنوان: |
Comparison of Gd-DTPA-Induced Signal Enhancements in Rat Brain C6 Glioma among Different Pulse Sequences in 3-Tesla Magnetic Resonance Imaging. |
| المؤلفون: |
Sato, H., Enmi, J., Teramoto, N., Hayashi, T., Yamamoto, A., Tsuji, T., Naito, H., Iida, H. |
| المصدر: |
Acta Radiologica; Apr2008, Vol. 49 Issue 2, p172-179, 8p, 2 Color Photographs, 2 Black and White Photographs, 4 Charts, 3 Graphs |
| مصطلحات موضوعية: |
MAGNETIC resonance imaging, LABORATORY rats, DIAGNOSTIC imaging, GLIOMAS, BRAIN tumors |
| مستخلص: |
Background: T1-shortening contrast media are routinely used in magnetic resonance (MR) examinations for the diagnosis of brain tumors. Although some studies show a benefit of 3 Tesla (T) compared to 1.5T in delineation of brain tumors using contrast media, it is unclear which pulse sequences are optimal. Purpose: To compare gadopentetate dimeglumine (Gd-DTPA)-induced signal enhancements in rat brain C6 glioma in the thalamus region among different pulse sequences in 3T MR imaging. Material and Methods: Five rats with a surgically implanted C6 glioma in their thalamus were examined. T1-weighted brain images of the five rats were acquired before and after Gd-DTPA administration (0.1 mmol/kg) using three clinically available pulse sequences (spin echo [SE], fast SE [FSE], fast spoiled gradient echo [FSPGR]) at 3T. Signal enhancement in the glioma (ET) was calculated as the signal intensity after Gd-DTPA administration scaled by that before administration. Pulse sequences were compared using the Tukey-Kramer test. Results: ET was 1.12±0.05 for FSE, 1.26±0.11 for FSPGR, and 1.20±0.11 for SE. FSPGR showed significantly higher signal enhancement than FSE and comparable enhancement to SE. Conclusion: FSPGR is superior to FSE and comparable to SE in its ability to delineate rat brain C6 glioma in the thalamus region. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
