دورية أكاديمية

A Prospective, Randomized Multicenter Study Comparing APD and CAPD Treatment

التفاصيل البيبلوغرافية
العنوان: A Prospective, Randomized Multicenter Study Comparing APD and CAPD Treatment
المؤلفون: Bro, Susanne, Bjorner, Jakob B., Tofte–Jensen, Pernille, Klem, Susanne, Almtoft, Birte, Danielsen, Henning, Meincke, Margot, Friedberg, Michael, Feldt–Rasmussen, Bo
المصدر: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis ; volume 19, issue 6, page 526-533 ; ISSN 0896-8608 1718-4304
بيانات النشر: SAGE Publications
سنة النشر: 1999
الوصف: Objective The goals for maintenance dialysis treatment are to improve patient survival, reduce patient morbidity, and improve patient quality of life. This is the first randomized prospective study comparing automated peritoneal dialysis (APD) and continuous ambulatory peritoneal dialysis (CAPD) treatment with respect to quality of life and clinical outcomes in relation to therapy costs. Design A prospective, randomized multicenter study. Setting Three Danish CAPD units. Patients Thirty-four adequately dialyzed patients with high or high-average peritoneal transport characteristics were included in the study. Twenty-five patients completed the study. Interventions After randomization, 17 patients were allocated to APD treatment and 17 patients to CAPD treatment for a period of 6 months. Medical and biochemical parameters were evaluated at monthly controls in the CAPD units. Quality-of-life parameters were assessed at baseline and after 6 months by the self-administered short-form SF-36 generic health survey questionnaire supplemented with disease- and treatment-specific questions. Therapy costs were compared by evaluating dialysis-related expenses. Main Outcome Measures Quality-of-life parameters, dialysis-related complications, dialysis-related expenses. Results The quality-of-life studies showed that significantly more time for work, family, and social activities was available to patients on APD compared to those on CAPD ( p < 0.001). Although the difference was not significant, there was a tendency for less physical and emotional discomfort caused by dialysis fluid in the APD group. Sleep problems, on the other hand, tended to be more marked in the APD group. Any positive effect of APD compared to CAPD on dialysis-related hospital days or complication rates could not be confirmed. With larger patient samples, it is possible, however, that a significant difference might have been achieved. The running costs for APD treatment were US $75 per day and for CAPD treatment US $61 per day. Conclusion If APD ...
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1177/089686089901900606
الإتاحة: https://doi.org/10.1177/089686089901900606Test
حقوق: http://journals.sagepub.com/page/policies/text-and-data-mining-licenseTest
رقم الانضمام: edsbas.D1BDCFB0
قاعدة البيانات: BASE