Long-Term Survival in a Case of Pleomorphic Carcinoma with a Brain Metastasis
| العنوان: | Long-Term Survival in a Case of Pleomorphic Carcinoma with a Brain Metastasis |
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| المؤلفون: | Koki Miura, Keiji Yamanashi, Satoshi Marumo, Masahiro Kawashima |
| المصدر: | Case Reports in Oncology Case Reports in Oncology, Vol 7, Iss 3, Pp 799-803 (2014) |
| بيانات النشر: | S. Karger AG, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Oncology, Chemotherapy, Lung cancer surgery, medicine.medical_specialty, business.industry, medicine.medical_treatment, Published online: December, 2014, Metastases, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, Pleomorphic carcinoma, lcsh:RC254-282, Gemcitabine, Internal medicine, medicine, Biomarker (medicine), Immunohistochemistry, Combined Modality Therapy, business, Adjuvant/neoadjuvant therapy, Brain metastasis, medicine.drug |
| الوصف: | Pleomorphic carcinoma (PC) is a rare malignant lung tumor with a poorer prognosis compared to other histological types of non-small cell lung cancer. However, several recent immunohistochemical studies revealed that a low MIB-1 index is a good prognostic marker in patients with PC. We report the case of a patient with PC and a single brain metastasis that achieved long-term recurrence-free survival following treatment with combined modality therapy. In this case, the MIB-1 index was reduced by gemcitabine-based chemotherapy, which may have led to long-term disease-free survival. The MIB-1 index may be a useful biomarker for the response to chemotherapy. |
| اللغة: | English |
| تدمد: | 1662-6575 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2249c52595be72297bf17099831301f1Test http://europepmc.org/articles/PMC4280452Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....2249c52595be72297bf17099831301f1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16626575 |
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