دورية أكاديمية

Subtemporal Decompression in Resistant Slit Ventricle Syndrome in Children: An Observational Study and Survival Analysis

التفاصيل البيبلوغرافية
العنوان: Subtemporal Decompression in Resistant Slit Ventricle Syndrome in Children: An Observational Study and Survival Analysis
المؤلفون: Khan, Mehdi, Craven, Claudia Louise, Tahir, Muhammad Zubair
المصدر: Pediatric Neurosurgery ; volume 58, issue 6, page 420-428 ; ISSN 1016-2291 1423-0305
بيانات النشر: S. Karger AG
سنة النشر: 2023
مصطلحات موضوعية: Neurology (clinical), General Medicine, Surgery, Pediatrics, Perinatology and Child Health
الوصف: Introduction: Slit ventricle syndrome (SVS) remains a challenging problem in the early-shunted paediatric population. Various surgical and non-surgical treatments have been devised for this condition. However, there is currently no gold standard for its optimal management. Among various treatment modalities, subtemporal decompression (STD) is often performed as a last resort. We present our experience of STD in paediatric patients with SVS in whom initial treatment with programmable valves and anti-syphon device were not successful. Methods: This is a single-centre retrospective observational study and survival analysis. Patients who underwent STD for SVS were included. Pre- and post-operative imaging data and clinical outcomes were collected. Results: There were 20 patients (12 M, 8 F) with a mean age of 9 years (SD: 4) at first STD. 90% ( n = 18) of patients had multiple shunt revisions pre-STD. At first STD, 70% ( n = 14) and 30% ( n = 6) of patients had unilateral or bilateral STD, respectively. STD led to a reduction in the frequency of shunt revisions in 60% ( n = 12) of patients. The median time required before further STD, shunt surgery, or cranial vault surgery was 14 months. The median time before a further STD was required (either revision or contralateral side) was 89 months. At a median follow-up of 66.5 months (range: 1–159), 65% ( n = 13) of patients had improvement in symptoms. Conclusions: A large proportion of patients with persistent SVS symptoms, refractory to multiple shunt revisions, benefitted from STD in combination with shunt optimization. It was also safe and well-tolerated. Therefore, in patients who have multiple failed shunts, STD may reduce the morbidity associated with further shunt revisions and can significantly improve symptomatology.
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1159/000534611
DOI: 10.1159/000534611/4046197/000534611.pdf
الإتاحة: https://doi.org/10.1159/000534611Test
حقوق: https://creativecommons.org/licenses/by/4.0Test/ ; https://creativecommons.org/licenses/by/4.0Test/
رقم الانضمام: edsbas.9391783C
قاعدة البيانات: BASE