Childhood Insulin-Dependent Diabetes mellitus: Initial Presentation and Management in the Nineties
| العنوان: | Childhood Insulin-Dependent Diabetes mellitus: Initial Presentation and Management in the Nineties |
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| المؤلفون: | Primus E. Mullis, Mario G. Bianchetti, Thomas Limbach, Anita C. Truttmann |
| المصدر: | Mineral and Electrolyte Metabolism. 24:326-329 |
| بيانات النشر: | S. Karger AG, 1998. |
| سنة النشر: | 1998 |
| مصطلحات موضوعية: | Blood Glucose, Male, medicine.medical_specialty, Pediatrics, Adolescent, endocrine system diseases, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Biochemistry, Electrolytes, Internal medicine, Diabetes mellitus, Immunopathology, medicine, Humans, Hypoglycemic Agents, Insulin, Child, Dehydration, business.industry, Metabolic disorder, Infant, nutritional and metabolic diseases, medicine.disease, Diabetes Mellitus, Type 1, Endocrinology, Ketoacidemia, El Niño, Child, Preschool, Insulin dependent diabetes, Fluid Therapy, Female, Presentation (obstetrics), business, Acids |
| الوصف: | Diabetes mellitus with onset during childhood usually presents as overt ketoacidemia. Pediatricians now inquire specifically about diabetes mellitus in children with nonspecific signs of illness and perform urinary dipstick testing. The present study was therefore performed to assess the possible influence of this strategy on the initial presentation and management of diabetes mellitus. The charts of 61 consecutive children with newly diagnosed diabetes mellitus (positive glucosuria and ketonuria and capillary glucose >14 mmol/l), who had been admitted between 1991 and 1996 at the Department of Pediatrics, University of Bern, Switzerland, were therefore reviewed. Twenty-six out of the 61 patients were nonacidemic (blood pH 7.36 or more). Children with and without acidemia did not differ with respect to age, history of polydipsia and polyuria, plasma glucose and circulating glycated hemoglobin A1c. The degree of dehydration and the amount of fluid required for its correction and the total insulin dosage were more prominent in the group of patients with acidemia. The study demonstrates that childhood diabetes mellitus is nowadays often recognized as nonacidemic hyperglycemia and that in these patients a reduced initial fluid repair and total insulin dosage is recommended. |
| تدمد: | 1423-016X 0378-0392 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3587142dba5f679154be7631e82b3bbeTest https://doi.org/10.1159/000057391Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....3587142dba5f679154be7631e82b3bbe |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1423016X 03780392 |
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