Preliminary Study on Glucose Control with an Artificial Pancreas in Postoperative Sepsis Patients
| العنوان: | Preliminary Study on Glucose Control with an Artificial Pancreas in Postoperative Sepsis Patients |
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| المؤلفون: | Gaku Takahashi, Masahiro Kojika, Koichi Hoshikawa, Naoya Matsumoto, Tomohiro Kikkawa, Keijiro Suzuki, Sigeatu Endo, Tatsuyori Shozushima, Go Wakabayashi, Shinji Akitomi, Nobuhiro Sato, Chiaki Onodera, Yoshihiro Inoue |
| المصدر: | European Surgical Research. 47:32-38 |
| بيانات النشر: | S. Karger AG, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Blood Glucose, Male, Pancreas, Artificial, medicine.medical_specialty, Glucose control, medicine.medical_treatment, Hypoglycemia, Artificial pancreas, Sepsis, Postoperative Complications, medicine, Humans, Insulin, Postoperative Period, Intensive care medicine, Aged, Retrospective Studies, business.industry, nutritional and metabolic diseases, Postoperative sepsis, Middle Aged, medicine.disease, Glucose, Anesthesia, Female, Surgery, business |
| الوصف: | Background: Glucose control is essential to avoid hypoglycemia in postoperative patients. Aim: To conduct a preliminary examination to evaluate the feasibility of the use of an artificial pancreas for glucose control as well as the accuracy of assessment by the artificial pancreas of the insulin dose required. Subjects and Methods: Glucose control using an artificial pancreas was undertaken in 8 postoperative sepsis patients. The blood glucose level was set at 80–150 mg/dl. Blood glucose levels over time, insulin dose requirements, and occurrence of hypoglycemia (≤40 mg/dl) were recorded for each patient. The patients were divided into 2 groups based on the total insulin dose they received over the 7 days (HG, n = 4: consisting of patients who required a higher insulin dose; LG, n = 4: patients who required a lower insulin dose). The data of the 2 groups were analyzed retrospectively. Results: The blood glucose level before glucose control was 203.3 ± 9.9 mg/dl and could be controlled in all patients to within the target range. No hypoglycemia events were recorded for any of the patients. The insulin dose in the HG and LG groups was 21,824.8 ± 6,030.4 and 6,254.5 ± 3,402.3 mU/kg (p < 0.05). Conclusions: Accurate glucose control could be achieved with the artificial pancreas. |
| تدمد: | 1421-9921 0014-312X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4cc258f279c760690750482d845a060Test https://doi.org/10.1159/000327971Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....a4cc258f279c760690750482d845a060 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14219921 0014312X |
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