Free Circulating Magnesium and Renal Magnesium Handling during Acute Metabolic Acidosis in Humans
| العنوان: | Free Circulating Magnesium and Renal Magnesium Handling during Acute Metabolic Acidosis in Humans |
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| المؤلفون: | Mario G. Bianchetti, Stellario Capillo, Vincenzo Jacomella, Jean P. Colombo, Alessandro Bonetti, Anita C. Truttmann, Daniel Blumberg, Christa M. Lüthy |
| المصدر: | American Journal of Nephrology. 18:233-236 |
| بيانات النشر: | S. Karger AG, 1998. |
| سنة النشر: | 1998 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, chemistry.chemical_element, Kidney, Ammonium Chloride, chemistry.chemical_compound, Internal medicine, medicine, Humans, Magnesium, Magnesium ion, Acidosis, business.industry, Kidney metabolism, Metabolic acidosis, medicine.disease, Endocrinology, chemistry, Nephrology, Acute Disease, Ammonium chloride, Hypermagnesiuria, medicine.symptom, Hypermagnesemia, business, Ion-Selective Electrodes |
| الوصف: | Ion-selective electrodes have been designed for determining the ionized concentration of magnesium in blood, the biologically active form of this ion. The effect of acute acidosis induced by ammonium loading on circulating and urinary magnesium was investigated in 11 volunteers. No changes in plasma total and ionized magnesium were noted following administration of ammonium chloride. On the contrary, administration of ammonium chloride increased the plasma free magnesium fraction and the urinary magnesium excretion. The study demonstrates that the hypermagnesiuria induced by acute acidosis is not caused by ionized hypermagnesemia and supports the theory that acidosis decreases the circulating magnesium fraction that is bound to proteins. |
| تدمد: | 1421-9670 0250-8095 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9bb0c42b8acc6a213d9c893c62066dfTest https://doi.org/10.1159/000013342Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....b9bb0c42b8acc6a213d9c893c62066df |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14219670 02508095 |
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