Acid promoted CIDT for the deracemization of dihydrocinnamic aldehydes with Betti's base
| العنوان: | Acid promoted CIDT for the deracemization of dihydrocinnamic aldehydes with Betti's base |
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| المؤلفون: | Paolo Righi, Emanuela Marotta, Francesco Tozzi, Claudio Paolucci, Goffredo Rosini, Francesca Boschi |
| المساهمون: | G. Rosini, C. Paolucci, F. Boschi, E. Marotta, P. Righi, F. Tozzi |
| المصدر: | Green Chemistry. 12:1747 |
| بيانات النشر: | Royal Society of Chemistry (RSC), 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | chemistry.chemical_classification, Chiral auxiliary, INDUCED ASYMMETRIC TRANSFORMATION, CONVERGENT SYNTHESIS, Base (chemistry), Stereochemistry, TRANS-CHRYSANTHEMIC ACID, RING-CHAIN TAUTOMERISM, AROMATIC-ALDEHYDES, Convergent synthesis, Diastereomer, Oxazines, ENANTIOSELECTIVE ADDITION, Cleavage (embryo), Ring (chemistry), ARYL ALDEHYDES, Pollution, Aldehyde, OPTICAL RESOLUTION, chemistry.chemical_compound, chemistry, Environmental Chemistry, CHEMOENZYMATIC SYNTHESIS, RENIN INHIBITOR ALISKIREN |
| الوصف: | Racemic alpha-epimerizable and unfunctionalized aldehydes have been converted into enantiomerically enriched mixtures through a sequence of (i) a conversion into the diastereoisomeric 3-substituted 1-phenyl-2,3-dihydro-1H-naphtho[1,2-e][1,3]oxazines by reaction with the (R)- or (S)-1-(alpha-aminobenzyl)-2-naphthol (Betti's base), (ii) an acid promoted crystallization-induced diastereoisomer transformation (CIDT), and (iii) a clean cleavage of the dihydro-1,3-naphthoxazinic ring of the enriched diastereoisomer, easily collected by filtration, allowing the recovery of the enantiomerically enriched aldehydes and the chiral auxiliary. |
| وصف الملف: | STAMPA |
| تدمد: | 1463-9270 1463-9262 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3fdd0a0dad6ddb75d9f692def520fcfTest https://doi.org/10.1039/c0gc00013bTest |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....e3fdd0a0dad6ddb75d9f692def520fcf |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14639270 14639262 |
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