Recent advances in biosensor devices for HER-2 cancer biomarker detection
| العنوان: | Recent advances in biosensor devices for HER-2 cancer biomarker detection |
|---|---|
| المؤلفون: | Supat Chupradit, Saade Abdalkareem Jasim, Dmitry Bokov, Mustafa Z. Mahmoud, Ali B. Roomi, Kadda Hachem, Mohammad Rudiansyah, Wanich Suksatan, Ramtin Bidares |
| المصدر: | Analytical Methods. 14:1301-1310 |
| بيانات النشر: | Royal Society of Chemistry (RSC), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | integumentary system, Receptor, ErbB-2, Neoplasms, General Chemical Engineering, Biomarkers, Tumor, General Engineering, Humans, Biosensing Techniques, Electrochemical Techniques, Analytical Chemistry |
| الوصف: | The human epidermal growth factor receptor 2 (HER-2) protein is a member of the epidermal growth factor receptor (EGFR or ErbB) family and is a transmembrane tyrosine kinase receptor. HER-2 is highly regulated in ovarian, lung, gastric, oral, and breast cancers. The low specificity, complexity, expensiveness and the lack of sensitivity are essential restrictions in traditional diagnosis methods such as FISH, immunohistochemistry and PCR and these disadvantages led to the need for more studies on alternative methods. Biosensor technology has greatly affected the quality of human life owing to its features including, sensitivity, specificity, and rapid diagnosis and monitoring of different patient diseases. In this review article, we examine various biosensors, considering that they have been categorized based on the transducers used including piezoelectric biosensors, optical sensors such as fluorescence and surface plasmon resonance, and electrochemical types for the diagnosis of HER-2 and the effectiveness of some drugs against that. Attention to developing some types of biosensor devices such as colorimetric biosensors for HER-2 detection can be an important point in future studies. |
| تدمد: | 1759-9679 1759-9660 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f173ac5655919d323d35256691e44ecTest https://doi.org/10.1039/d2ay00111jTest |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....5f173ac5655919d323d35256691e44ec |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17599679 17599660 |
|---|