دورية أكاديمية
A two-step resin based approach to reveal survivin-selective fluorescent probes
| العنوان: | A two-step resin based approach to reveal survivin-selective fluorescent probes |
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| المؤلفون: | Ambrose, Andrew J., Pham, Nhan T., Sivinski, Jared, Guimarães, Larissa, Mollasalehi, Niloufar, Jimenez, Paula, Abad, Maria A., Jeyaprakash, A. Arockia, Shave, Steven, Costa-Lotufo, Letícia V., La Clair, James J., Auer, Manfred, Chapman, Eli |
| المساهمون: | Wellcome Trust, University of Arizona, Fundação de Amparo à Pesquisa do Estado de São Paulo, Conselho Nacional de Desenvolvimento Científico e Tecnológico, Medical Research Council |
| المصدر: | RSC Chemical Biology ; volume 2, issue 1, page 181-186 ; ISSN 2633-0679 |
| بيانات النشر: | Royal Society of Chemistry (RSC) |
| سنة النشر: | 2021 |
| الوصف: | A dual-resin system was developed that united confocal-fluorescent imaging for hit identification and microscale NMR for hit isolation and structure elucidation. Using this approach, we identified two natural products that bound to the inhibitor of apoptosis protein, survivin. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1039/d0cb00122h |
| الإتاحة: | https://doi.org/10.1039/d0cb00122hTest http://pubs.rsc.org/en/content/articlepdf/2021/CB/D0CB00122HTest |
| حقوق: | http://creativecommons.org/licenses/by/3.0Test/ |
| رقم الانضمام: | edsbas.5D226953 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1039/d0cb00122h |
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