Amorphous alumina nanowire array efficiently delivers Ac-DEVD-CHO to inhibit apoptosis of dendritic cells
| العنوان: | Amorphous alumina nanowire array efficiently delivers Ac-DEVD-CHO to inhibit apoptosis of dendritic cells |
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| المؤلفون: | Brittany Timonen, Lampert Lester, Haiyan Li, Jun Jiao, John F. Conley, Sean W. Smith, Jeffrey D. Singer, Brittney Davidge |
| المصدر: | Chem. Commun.. 50:1234-1237 |
| بيانات النشر: | Royal Society of Chemistry (RSC), 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Materials science, Nanowire, Apoptosis, Nanotechnology, CHO Cells, Carbon nanotube, Article, Catalysis, law.invention, Atomic layer deposition, Cricetulus, Drug Delivery Systems, Microscopy, Electron, Transmission, law, Aluminum Oxide, Materials Chemistry, Fluorescence microscope, Animals, Caspase 7, Caspase 3, Nanowires, technology, industry, and agriculture, Metals and Alloys, Dendritic Cells, General Chemistry, Caspase Inhibitors, Nanowire array, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Amorphous solid, Ac-DEVD-CHO, Ceramics and Composites, Powders |
| الوصف: | To create an effective well-ordered delivery platform still remains a challenge. Herein we fabricate vertically aligned alumina nanowire arrays via atomic layer deposition templated by carbon nanotubes. Using these arrays, a caspase-3/7 inhibitor was delivered into DC 2.4 cells and blocked apoptosis, as confirmed by fluorescence microscopy. |
| تدمد: | 1364-548X 1359-7345 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c298973c3bb968d0c3a15ce1aed7bd3bTest https://doi.org/10.1039/c3cc48088gTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....c298973c3bb968d0c3a15ce1aed7bd3b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1364548X 13597345 |
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