التفاصيل البيبلوغرافية
| العنوان: |
Impact of body mass index on IVF and ICSI outcome: a retrospective study. |
| المؤلفون: |
Matalliotakis, Ioannis1,2 matakgr@yahoo.com, Cakmak, Hakan1, Sakkas, Denny1, Mahutte, Neal1, Koumantakis, Georgios2, Arici, Aydin1 |
| المصدر: |
Reproductive BioMedicine Online (Reproductive Healthcare Limited). Jun2008, Vol. 16 Issue 6, p778-783. 6p. |
| مصطلحات موضوعية: |
*BODY mass index, *HUMAN in vitro fertilization, *HUMAN artificial insemination, *GONADOTROPIN, *PREGNANCY |
| مستخلص: |
A group of 140 women with a body mass index (BMI) ≤ 24 kg/m² undergoing 291 cycles was compared with a group of 138 women with a BMI >24 kg/m² in 291 cycles, with respect to duration of ovarian stimulation and dose of gonadotrophin, number of oocytes collected, cleavage and implantation rate, clinical pregnancy, miscarriage and delivery rates. Patients with a BMI > 24 kg/m² demonstrated a significant decrease in the number of follicles after stimulation (P = 0.01), a comparative increase in the number ampoules of gonadotrophin used (P = 0.03) and a lower number of eggs collected (P = 0.05). The mean number of embryos on days 1, 2 and 3 was significantly lower in the group with BMI > 24 kg/m² (P < 0.001). No significant difference was found in clinical pregnancy and miscarriage rates between the two groups. In spite of the lower response in women with BMI > 24 kg/m², the delivery rate per retrieval was not different (24.6 versus 24.8%). These results indicate a lower stimulation response in women with elevated BMI, but no adverse effect on IVF outcome. In relation to wellbeing, however, it is recommended that patients with a high BMI reduce their weight before IVF treatment. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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