Safety and vaccine-induced HIV-1 immune responses in healthy volunteers following a late MVA-B boost 4 years after the last immunization
| العنوان: | Safety and vaccine-induced HIV-1 immune responses in healthy volunteers following a late MVA-B boost 4 years after the last immunization |
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| المؤلفون: | Guardo AC, Gómez CE, Vicens Diaz de Brito Fernandez, Pich J, Arnaiz JA, Perdiguero B, García-Arriaza J, González N, Sorzano COS, Jiménez L, Jiménez JL, Muñoz-Fernández MÁ, Gatell JM, Alcamí J, Esteban M, López Bernaldo de Quirós JC, García F, Plana M, RISVAC02boost study |
| المصدر: | PLoS One r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu Fundació Sant Joan de Déu r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu instname |
| بيانات النشر: | PUBLIC LIBRARY SCIENCE, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | viruses, complex mixtures |
| الوصف: | We have previously shown that an HIV vaccine regimen including three doses of HIV-modified vaccinia virus Ankara vector expressing HIV-1 antigens from clade B (MVA-B) was safe and elicited moderate and durable (1 year) T-cell and antibody responses in 75% and 95% of HIV-negative volunteers (n = 24), respectively (RISVAC02 study). Here, we describe the long-term durability of vaccine-induced responses and the safety and immunogenicity of an additional MVA-B boost. |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::57bfbaf1e6bd99b42aa6d7966ce2407aTest http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=14292Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.dedup.wf.001..57bfbaf1e6bd99b42aa6d7966ce2407a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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