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المؤلفون: Cécile Ribot, Cédric Soler, Aymeric Chartier, Sandy Al Hayek, Rima Naït-Saïdi, Nicolas Barbezier, Olivier Coux, Martine Simonelig
المساهمون: Institut de génétique humaine (IGH), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Université Clermont Auvergne (UCA), Génétique, Reproduction et Développement (GReD), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA), Centre de recherche en Biologie cellulaire de Montpellier (CRBM)
المصدر: PLoS Genetics, Vol 18, Iss 1, p e1010015 (2022)
PLoS Genetics
PLoS Genetics, 2022, 18 (1), pp.e1010015. ⟨10.1371/journal.pgen.1010015⟩مصطلحات موضوعية: Life Cycles, Genetic Screens, Cancer Research, Heredity, Leupeptins, [SDV]Life Sciences [q-bio], Gene Identification and Analysis, Muscle Proteins, Pathogenesis, QH426-470, Pathology and Laboratory Medicine, Biochemistry, Poly(A)-Binding Protein I, Suppressor Genes, Larvae, Medicine and Health Sciences, Genetics (clinical), Heterozygosity, Drosophila Melanogaster, Eukaryota, Animal Models, Insects, Muscular Atrophy, Experimental Organism Systems, Drosophila, Research Article, Proteasome Endopeptidase Complex, Arthropoda, Research and Analysis Methods, Proof of Concept Study, Protein Aggregates, Model Organisms, Muscular Dystrophy, Oculopharyngeal, Gene Types, Genetics, Animals, Humans, Genetic Testing, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Ubiquitin, Organisms, Biology and Life Sciences, Proteins, Protein Complexes, Proteasomes, Invertebrates, Disease Models, Animal, Gene Expression Regulation, Mutation, Animal Studies, Zoology, Entomology, Developmental Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c39c64adaa3353b2b4a97f01ff0ef62Test
https://doaj.org/article/c0ad9bc556604a2a99af3e68628adc08Test -
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المؤلفون: Annika Kratzel, Jenna N. Kelly, Philip V’kovski, Jasmine Portmann, Yannick Brüggemann, Daniel Todt, Nadine Ebert, Neeta Shrestha, Philippe Plattet, Claudia A. Staab-Weijnitz, Albrecht von Brunn, Eike Steinmann, Ronald Dijkman, Gert Zimmer, Stephanie Pfaender, Volker Thiel
المصدر: PLoS Biology, Vol 19, Iss 12, p e3001490 (2021)
PLoS Biology
Kratzel, Annika; Kelly, Jenna N; V'kovski, Philip; Portmann, Jasmine; Brüggemann, Yannick; Todt, Daniel; Ebert, Nadine; Shrestha, Neeta; Plattet, Philippe; Staab-Weijnitz, Claudia A; von Brunn, Albrecht; Steinmann, Eike; Dijkman, Ronald; Zimmer, Gert; Pfaender, Stephanie; Thiel, Volker (2021). A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets. PLoS biology, 19(12), e3001490. Public Library of Science 10.1371/journal.pbio.3001490 <http://dx.doi.org/10.1371/journal.pbio.3001490Test>مصطلحات موضوعية: RNA viruses, Genetic Screens, Pulmonology, Coronaviruses, viruses, Gene Identification and Analysis, Pathology and Laboratory Medicine, Virus Replication, Synthetic Genome Editing, Genome Engineering, Medical Conditions, 0302 clinical medicine, Short Reports, Medicine and Health Sciences, Biology (General), 610 Medicine & health, 0303 health sciences, Cell Death, 630 Agriculture, Gene Ontologies, General Neuroscience, Crispr, virus diseases, Genomics, respiratory system, 3. Good health, Infectious Diseases, Medical Microbiology, Cell Processes, Viral Pathogens, Gene Knockdown Techniques, Viruses, Host-Pathogen Interactions, Middle East Respiratory Syndrome Coronavirus, Engineering and Technology, Synthetic Biology, Pathogens, SARS CoV 2, General Agricultural and Biological Sciences, SARS coronavirus, QH301-705.5, Autophagic Cell Death, Bioengineering, Microbiology, Antiviral Agents, General Biochemistry, Genetics and Molecular Biology, Respiratory Disorders, 03 medical and health sciences, Virology, Genetics, Autophagy, Humans, Microbial Pathogens, 030304 developmental biology, Biology and life sciences, General Immunology and Microbiology, SARS-CoV-2, Organisms, Computational Biology, Cell Biology, Synthetic Genomics, biochemical phenomena, metabolism, and nutrition, Genome Analysis, Viral Replication, respiratory tract diseases, Respiratory Infections, 570 Life sciences, biology, CRISPR-Cas Systems, 030217 neurology & neurosurgery
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4ab2fc971b84f1ee3eb0002daede3eTest
https://doaj.org/article/54681cf4677643fdb49590be289c3086Test -
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المؤلفون: Simon Mead, Simone Hornemann, Marc Emmenegger, Elke Schaper, Kevin Maggi, Peter Heutink, Jiang-An Yin, Anna Spinelli, Ashutosh Dhingra, Daniel Heinzer, Berre Doğançay, Merve Avar, Daniel Patrick Pease, Adriano Aguzzi, Andra Chincisan
المساهمون: University of Zurich, Bartz, Jason C, Aguzzi, Adriano
المصدر: PLoS Pathogens, Vol 17, Iss 10 (2021)
PLoS pathogens 17(10), e1010013 (2021). doi:10.1371/journal.ppat.1010013
PLoS Pathogens, Vol 17, Iss 10, p e1010013 (2021)
PLoS Pathogensمصطلحات موضوعية: Genetic Screens, Small interfering RNA, animal diseases, Gene Identification and Analysis, 2405 Parasitology, Biochemistry, Fluorophotometry, Prion Diseases, Guide RNA, Medical Conditions, Spectrum Analysis Techniques, RNA interference, Zoonoses, Medicine and Health Sciences, Fluorescence Resonance Energy Transfer, Biology (General), 2404 Microbiology, RNA-Binding Proteins, Phenotype, Cell biology, Nucleic acids, Infectious Diseases, Spectrophotometry, RNA Interference, biosynthesis [PrPC Proteins], Research Article, QH301-705.5, Immunoblotting, Immunology, physiology [Gene Expression Regulation], 10208 Institute of Neuropathology, Molecular Probe Techniques, Repressor, 610 Medicine & health, Context (language use), Biology, Transfection, Research and Analysis Methods, metabolism [RNA-Binding Proteins], Microbiology, Cell Line, 1311 Genetics, Gene Types, Virology, mental disorders, 1312 Molecular Biology, Genetics, Humans, PrPC Proteins, ddc:610, Non-coding RNA, Molecular Biology Techniques, Molecular Biology, Gene, 2403 Immunology, CRISPR interference, Biology and life sciences, RC581-607, Gene regulation, nervous system diseases, Gene Expression Regulation, 2406 Virology, RNA, Regulator Genes, 570 Life sciences, biology, Parasitology, Human genome, Gene expression, Immunologic diseases. Allergy, Genome-Wide Association Study
وصف الملف: journal.ppat.1010013.pdf - application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f070e22194fd9e3258e126ce44b9beTest
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575309/?tool=EBITest -
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المؤلفون: Minji Jeon, Justin Guinney, Zhaoping Xiong, Donghyeon Park, Jinhyuk Lee, Robert J. Allaway, Heather A. Carlson, Ruben Abagyan, Tirtha K. Das, Chana Hecht, Hwisang Jeon, Xindi Guo, Miyoung Ko, Aik Choon Tan, Alexander Tropsha, Jaewoo Kang, Multi-Targeting Drug Dream Challenge Community, Ross L. Cagan, Kristen K. Dang, Mingyue Zheng, Hualiang Jiang, Avner Schlessinger
المساهمون: Wang, Edwin
المصدر: PLoS Computational Biology, Vol 17, Iss 9, p e1009302 (2021)
PLoS computational biology, vol 17, iss 9
PLoS Computational Biologyمصطلحات موضوعية: Genetic Screens, Heredity, Computer science, Polypharmacology, Gene Identification and Analysis, Disease, Drug resistance, Mathematical Sciences, Machine Learning, Genetic Suppression, Multi target, SAFER, Neoplasms, Medicine and Health Sciences, Biology (General), media_common, Multi targeting, Ecology, Drosophila Melanogaster, Eukaryota, Animal Models, Biological Sciences, Multi-Targeting Drug DREAM Challenge Community, Insects, Computational Theory and Mathematics, Experimental Organism Systems, Drug development, Tauopathies, 5.1 Pharmaceuticals, Modeling and Simulation, Drosophila, Identification (biology), Development of treatments and therapeutic interventions, Genetic Dominance, Research Article, Drug, Modern medicine, Computer and Information Sciences, Drug Research and Development, Arthropoda, Neural Networks, Bioinformatics, QH301-705.5, media_common.quotation_subject, tau Proteins, Computational biology, Research and Analysis Methods, Cellular and Molecular Neuroscience, Computer, Model Organisms, Rare Diseases, Drug Development, Artificial Intelligence, Information and Computing Sciences, Genetics, Animals, Humans, Molecular Biology, Protein Kinase Inhibitors, Ecology, Evolution, Behavior and Systematics, Pharmacology, Drug Screening, Proto-Oncogene Proteins c-ret, Organisms, Biology and Life Sciences, Invertebrates, Brain Disorders, Orphan Drug, Good Health and Well Being, Biological target, Molecular targets, Animal Studies, Neural Networks, Computer, Zoology, Entomology, Neuroscience
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a46796ee0a1cbcc1a192e14e0abf555Test
https://doaj.org/article/760d14f1687d40cc99f25eb1a90cecb7Test -
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المؤلفون: David A. Lyons, Themistoklis M. Tsarouchas, Catherina G. Becker, Thomas Becker, Hui-Hsin Tsai, Juan Larraz, Davide Gianni, Tahimina Munir, Marcus Keatinge, Nicola J. Porter
المصدر: PLoS Genetics, Vol 17, Iss 4, p e1009515 (2021)
PLoS Geneticsمصطلحات موضوعية: Life Cycles, Genetic Screens, Cancer Research, Critical Care and Emergency Medicine, Neutrophils, Gene Identification and Analysis, QH426-470, Nervous System, White Blood Cells, Larvae, 0302 clinical medicine, Animal Cells, Morphogenesis, Medicine and Health Sciences, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, Osteonectin, Spinal Cord Injury, Zebrafish, Spinal cord injury, Trauma Medicine, Genetics (clinical), 0303 health sciences, biology, Eukaryota, Animal Models, Phenotype, Cell biology, Spinal Cord, Experimental Organism Systems, Neurology, Osteichthyes, Vertebrates, Anatomy, Cellular Types, Traumatic Injury, RNA, Guide, Kinetoplastida, Research Article, Spinal Cord Regeneration, Immune Cells, Phenotypic screening, Immunology, Research and Analysis Methods, Transforming Growth Factor beta1, 03 medical and health sciences, Transforming Growth Factor beta3, Model Organisms, medicine, Genetics, Animals, Regeneration, Molecular Biology, Spinal Cord Injuries, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Blood Cells, Macrophages, Regeneration (biology), Organisms, Biology and Life Sciences, Recovery of Function, Cell Biology, Zebrafish Proteins, biology.organism_classification, medicine.disease, Axons, Disease Models, Animal, Neuroanatomy, Fish, Animal Studies, Organism Development, Zoology, Neurotrauma, 030217 neurology & neurosurgery, Developmental Biology, Neuroscience, Genetic screen
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9f2e00cacb7fb7e9f1d67c3a37a637Test
https://doaj.org/article/ebb1d8e5ba6e43a49ae28bb01edfb043Test -
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المؤلفون: Mordechai Shohat, Keren Hod, Ifat Abadi-Korek, Rami Moshonov, Bella Azaria, Rachel Berger
المصدر: PLoS ONE, Vol 16, Iss 4, p e0250734 (2021)
PLoS ONEمصطلحات موضوعية: 0301 basic medicine, Genetic Screens, Databases, Factual, Epidemiology, Maternal Health, Gene Identification and Analysis, Chromosome Disorders, 030105 genetics & heredity, 0302 clinical medicine, Pregnancy, Risk Factors, Prenatal Diagnosis, Medicine and Health Sciences, Termination of Pregnancy, health care economics and organizations, Not evaluated, education.field_of_study, 030219 obstetrics & reproductive medicine, Multidisciplinary, medicine.diagnostic_test, Obstetrics, Gestational age, Obstetrics and Gynecology, humanities, Obstetric Procedures, Cohort, Amniocentesis, Medicine, Female, Karyotypes, Research Article, Adult, medicine.medical_specialty, Science, Population, Prenatal diagnosis, Surgical and Invasive Medical Procedures, Gestational Age, Congenital Abnormalities, 03 medical and health sciences, Cytogenetics, Diagnostic Medicine, medicine, Genetics, Humans, education, Management of High-Risk Pregnancies, Fetal Death, Retrospective Studies, Chromosome Aberrations, business.industry, Biology and Life Sciences, Retrospective cohort study, Human Genetics, medicine.disease, Microarray Analysis, Medical Risk Factors, Karyotyping, Women's Health, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e635de061e67bfe1bc34597daa47d076Test
https://doaj.org/article/c180885efc3b4c9fa1ae55524ff38e68Test -
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المؤلفون: Shu Ching Yang, Nan Haw Chow, Hung Wen Tsai, Yi Lin Chen, Wan Li Chen, Yi Chia Cheng, Ming Ching Lin, Chung Liang Ho, Wu Chou Su, Chien Chung Lin
المصدر: PLoS ONE, Vol 16, Iss 9, p e0257152 (2021)
PLoS ONEمصطلحات موضوعية: Male, Genetic Screens, Lung Neoplasms, Tissue Fixation, Pulmonology, Gene Identification and Analysis, Artificial Gene Amplification and Extension, Cell Cycle Proteins, Polymerase Chain Reaction, Lung and Intrathoracic Tumors, Fusion gene, Cohort Studies, Carcinoma, Non-Small-Cell Lung, hemic and lymphatic diseases, Fusion Genes, Medicine and Health Sciences, Anaplastic lymphoma kinase, Anaplastic Lymphoma Kinase, Early Detection of Cancer, Aged, 80 and over, Gene Rearrangement, Multidisciplinary, Paraffin Embedding, medicine.diagnostic_test, Fluorescent in Situ Hybridization, Serine Endopeptidases, ALK Gene Amplification, DNA, Neoplasm, Middle Aged, Reverse transcription polymerase chain reaction, ErbB Receptors, Oncology, Immunohistochemistry, Medicine, Female, Microtubule-Associated Proteins, medicine.drug, Research Article, Adult, medicine.drug_class, Science, Molecular Probe Techniques, Biology, Research and Analysis Methods, Crizotinib, Gene Types, Formaldehyde, medicine, Genetics, Humans, Molecular Biology Techniques, Molecular Biology, Aged, Cell Proliferation, Base Sequence, Biology and Life Sciences, Cancers and Neoplasms, Reverse Transcriptase-Polymerase Chain Reaction, Probe Hybridization, Non-Small Cell Lung Cancer, Pleural Effusion, Malignant, ALK inhibitor, Pleural Effusion, HEK293 Cells, Cancer research, Cytogenetic Techniques, Fluorescence in situ hybridization
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355452b6148c9af2365141e1010607f4Test
https://doaj.org/article/f237227974f540cd9dec0686f2f84839Test -
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المؤلفون: Yong-Ming Zhang, Zhen-Shan Huang, Peng-Cheng Deng, Shao-Nian Xu, Peng-Cheng Zhao
المصدر: PLoS ONE, Vol 16, Iss 6, p e0253219 (2021)
PLoS ONEمصطلحات موضوعية: Genetic Screens, Gene Identification and Analysis, Gene Expression, Genetic Networks, Vascular Medicine, Mathematical and Statistical Techniques, Databases, Genetic, Medicine and Health Sciences, Cluster Analysis, Medicine, Stroke, Principal Component Analysis, Multidisciplinary, Applied Mathematics, Simulation and Modeling, Statistics, Head injury, Vasospasm, Physical Sciences, Cardiology, Aneurysms, Algorithms, Network Analysis, Research Article, Genetic Markers, Computer and Information Sciences, medicine.medical_specialty, Subarachnoid hemorrhage, Science, Wavelet Analysis, Hemorrhage, Research and Analysis Methods, Signs and Symptoms, Text mining, Aneurysm, Internal medicine, Genetics, Humans, Gene Regulation, Vascular Diseases, cardiovascular diseases, Statistical Methods, Gene, business.industry, Genetic Algorithms, Biology and Life Sciences, Subarachnoid Hemorrhage, medicine.disease, nervous system diseases, Multivariate Analysis, Clinical Medicine, business, Complication, Mathematics
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd234973477bb5afa3d44617b671749Test
https://doaj.org/article/ba07e5a3fb234db6b0b99f5df507a34dTest -
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المؤلفون: Todd Lamitina, Sarel J. Urso, Marcella E. Comly, John A. Hanover
المصدر: PLoS Genetics, Vol 16, Iss 10, p e1008821 (2020)
PLoS Geneticsمصطلحات موضوعية: Threonine, Cancer Research, Genetic Screens, Nematoda, Regulator, Gene Identification and Analysis, QH426-470, Synthetic Genome Editing, Biochemistry, Genome Engineering, 0302 clinical medicine, Fluorescence Microscopy, RNA interference, Gene expression, Serine, Genetics (clinical), Caenorhabditis elegans, Hypertonic, Regulation of gene expression, 0303 health sciences, Microscopy, biology, Physics, Crispr, Classical Mechanics, Eukaryota, Light Microscopy, Animal Models, Phenotype, Cell biology, Nucleic acids, Experimental Organism Systems, Genetic interference, Caenorhabditis Elegans, Physical Sciences, Engineering and Technology, Synthetic Biology, Epigenetics, Research Article, Cell physiology, Osmotic shock, Bioengineering, Research and Analysis Methods, N-Acetylglucosaminyltransferases, Gene Expression Regulation, Enzymologic, 03 medical and health sciences, Model Organisms, Protein Domains, Osmotic Pressure, Osmotic Shock, Pressure, Genetics, Tonicity, Animals, Humans, Caenorhabditis elegans Proteins, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Alleles, 030304 developmental biology, Organisms, Biology and Life Sciences, Cell Biology, Synthetic Genomics, biology.organism_classification, Invertebrates, Genetic Loci, Animal Studies, Caenorhabditis, RNA, Zoology, Protein Processing, Post-Translational, 030217 neurology & neurosurgery, Function (biology), Genetic screen
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442ad0fd1b04815ea933ba94b8e9d0ddTest
https://doaj.org/article/3fa1c93e13fa43c99537f5a94d3edc83Test -
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المؤلفون: Meijuan Zou, Ze-Hua Zuo, Jie Liu, Shihui Liu, Toren Finkel
المصدر: PLoS Genetics, Vol 16, Iss 10, p e1009068 (2020)
PLoS Geneticsمصطلحات موضوعية: Genetic Screens, Cancer Research, Gene Identification and Analysis, QH426-470, Toxicology, Pathology and Laboratory Medicine, Biochemistry, Synthetic Genome Editing, Genome Engineering, Mice, chemistry.chemical_compound, 0302 clinical medicine, Medicine and Health Sciences, Transcriptional regulation, Toxins, CRISPR, DPH1, Promoter Regions, Genetic, Genetics (clinical), 0303 health sciences, DNA methylation, Crispr, Diphthamide, Chromatin, Cell biology, Nucleic acids, BTB-POZ Domain, Engineering and Technology, Cell lines, Synthetic Biology, Epigenetics, DNA modification, Biological cultures, HT1080 cells, Chromatin modification, Research Article, Chromosome biology, Protein Binding, Elongation Factor 2 Kinase, Toxic Agents, Kruppel-Like Transcription Factors, Bioengineering, Library Screening, Biology, Research and Analysis Methods, Biosynthesis, Transfection, EEF2, Minor Histocompatibility Antigens, 03 medical and health sciences, Genetics, Animals, Humans, Histidine, Molecular Biology Techniques, Molecular Biology, Transcription factor, Gene, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Molecular Biology Assays and Analysis Techniques, Tumor Suppressor Proteins, Biology and Life Sciences, DNA, Methyltransferases, Synthetic Genomics, RAW 264.7 Cells, Gene Expression Regulation, chemistry, Gene expression, CRISPR-Cas Systems, Protein Processing, Post-Translational, 030217 neurology & neurosurgery, Transcription Factors, Genetic screen
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cffa06431989884ec76f1e2880660d0Test
https://doaj.org/article/6ac3396df3a045af88f197e3358f5047Test
