دورية أكاديمية
Association between serum ferritin level and decreased diffusion capacity 3 months after the onset of COVID-19 pneumonia
| العنوان: | Association between serum ferritin level and decreased diffusion capacity 3 months after the onset of COVID-19 pneumonia |
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| المؤلفون: | Kyota Shinfuku, Naoki Takasaka, Taiki Fukuda, Kentaro Chida, Yudai Suzuki, Shun Shibata, Ayako Kojima, Tsukasa Hasegawa, Masami Yamada, Yumie Yamanaka, Yusuke Hosaka, Aya Seki, Yoshitaka Seki, Hiroshi Takeda, Takeo Ishikawa, Kazuyoshi Kuwano |
| المصدر: | PLoS ONE, Vol 18, Iss 2 (2023) |
| بيانات النشر: | Public Library of Science (PLoS), 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Medicine, Science |
| الوصف: | Background Coronavirus disease 2019 (COVID-19) pneumonia can have prolonged sequelae and lead to respiratory dysfunction, mainly because of impaired diffusion capacity for carbon monoxide (DLCO). The clinical factors associated with DLCO impairment, including blood biochemistry test parameters, remain unclear. Methods Patients with COVID-19 pneumonia who underwent inpatient treatment between April 2020 and August 2021 were included in this study. A pulmonary function test was performed 3 months after onset, and the sequelae symptoms were investigated. Clinical factors, including blood test parameters and abnormal chest shadows on computed tomography, of COVID-19 pneumonia associated with DLCO impairment were investigated. Results In total, 54 recovered patients participated in this study. Twenty-six patients (48%) and 12 patients (22%) had sequelae symptoms 2 and 3 months after, respectively. The main sequelae symptoms at 3 months were dyspnea and general malaise. Pulmonary function tests showed that 13 patients (24%) had both DLCO 686.5 ng/mL (odds ratio: 11.08, 95% confidence interval [CI]: 1.84–66.59; p = 0.009) was most strongly associated with DLCO impairment. Conclusions Decreased DLCO was the most common respiratory function impairment, and ferritin level was a significantly associated clinical factor. Serum ferritin level could be used as a predictor of DLCO impairment in cases of COVID-19 pneumonia. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1932-6203 |
| العلاقة: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934337/?tool=EBITest; https://doaj.org/toc/1932-6203Test |
| الوصول الحر: | https://doaj.org/article/a0cc1fe79b484280ba5c135daeec80a0Test |
| رقم الانضمام: | edsdoj.0cc1fe79b484280ba5c135daeec80a0 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19326203 |
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