المؤلفون: Adriaan P. IJzerman, Johan Åqvist, Willem Jespers, Hugo Gutiérrez-de-Terán, Laura H. Heitman, Eddy Sotelo, Gerard J. P. van Westen

المصدر: PLoS Computational Biology, 17(11)
PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 11, p e1009152 (2021)

مصطلحات موضوعية: Models, Molecular, Partial Agonists, Conformational change, Adenosine, Protein Conformation, Ribose, Glycobiology, Ligands, Biochemistry, Medicine and Health Sciences, Biology (General), Receptor, Free Energy, Bioinformatics (Computational Biology), Crystallography, Ecology, Organic Compounds, Chemistry, Physics, Monosaccharides, Drugs, Nucleosides, Condensed Matter Physics, Ligand (biochemistry), Glycosylamines, Adenosine A2 Receptor Antagonists, Computational Theory and Mathematics, Modeling and Simulation, Physical Sciences, Crystal Structure, Thermodynamics, Research Article, Signal Transduction, medicine.drug, Transmembrane Receptors, Adenosine A2 Receptor Agonists, Receptor, Adenosine A2A, QH301-705.5, Carbohydrates, Molecular Dynamics Simulation, Free energy perturbation, Cellular and Molecular Neuroscience, Genetics, medicine, Point Mutation, Solid State Physics, Humans, Molecular Biology, Ecology, Evolution, Behavior and Systematics, G protein-coupled receptor, Pharmacology, Point mutation, Organic Chemistry, Chemical Compounds, Biology and Life Sciences, Proteins, Computational Biology, Cell Biology, Adenosine receptor, Amino Acid Substitution, Mutation, Bioinformatik (beräkningsbiologi), Biophysics, G Protein Coupled Receptors

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2140e01a0a4fe6b35c8fab97cb2fa113Test
https://doi.org/10.1371/journal.pcbi.1009152Test

المؤلفون: Fabrizio Vincenzi, Marco Viganò, Enrico Ragni, Alessandra Colombini, Paola De Luca, Katia Varani, Carlotta Perucca Orfei, Laura de Girolamo, Stefania Setti

المصدر: PLoS ONE, Vol 15, Iss 9, p e0239807 (2020)

مصطلحات موضوعية: 0301 basic medicine, Agonist, Adenosine A2 Receptor Agonists, Receptor, Adenosine A2A, medicine.drug_class, Cells, Science, Interleukin-1beta, Socio-culturale, Down-Regulation, Context (language use), Stimulation, Inflammation, Tendons, 03 medical and health sciences, Adenosine A2A, 0302 clinical medicine, Electromagnetic Fields, Downregulation and upregulation, medicine, Basic Helix-Loop-Helix Transcription Factors, Humans, Secretion, Cells, Cultured, Multidisciplinary, Cultured, Chemistry, Interleukin-6, Interleukin-33, Adenosine receptor, Adenosine, Collagen Type III, Cytokines, Up-Regulation, Cell biology, 030104 developmental biology, Medicine, medicine.symptom, 030217 neurology & neurosurgery, medicine.drug, Receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::946743bb1db8a6bd2d7ea3a8a3bcc6cbTest
https://doaj.org/article/1e926f8f6f0b440a9bb49c9e10d9e7acTest

المؤلفون: Carmen Diniz, Manuela Morato, Carla M. Abreu, Olga Mariana Cunha, Joana Afonso, Daniela Patinha, Carla Carvalho, António Albino-Teixeira, Mariana C. Mota

المصدر: PLoS ONE, Vol 14, Iss 5, p e0217552 (2019)
PLoS ONE

مصطلحات موضوعية: Male, 0301 basic medicine, Adenosine, Glycobiology, Adenosine A2A receptor, Blood Pressure, Immunostaining, Kidney, Biochemistry, Immune Receptors, Vascular Medicine, Diabetic nephropathy, Endocrinology, 0302 clinical medicine, Rats, Inbred SHR, Medicine and Health Sciences, Medicine, Diabetic Nephropathies, Receptor, Staining, Immune System Proteins, Multidisciplinary, Nucleosides, Glycosylamines, Precipitation Techniques, 3. Good health, medicine.anatomical_structure, Hypertension, Anatomy, Glomeruli, Research Article, Signal Transduction, medicine.drug, medicine.medical_specialty, Receptor, Adenosine A2A, Endocrine Disorders, Science, Immunology, Down-Regulation, Research and Analysis Methods, Streptozocin, Diabetes Mellitus, Experimental, 03 medical and health sciences, Downregulation and upregulation, Internal medicine, Diabetes mellitus, Diabetes Mellitus, Animals, Humans, Immunoprecipitation, business.industry, Biology and Life Sciences, Proteins, Kidneys, Cell Biology, Renal System, medicine.disease, Adenosine receptor, Rats, 030104 developmental biology, Specimen Preparation and Treatment, Metabolic Disorders, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703d153de9497cc48db4fa6bc6d33c6aTest
https://doi.org/10.1371/journal.pone.0217552Test

المؤلفون: Cuiying Xiao, Marc L. Reitman, Naili Liu, Oksana Gavrilova, Kenneth A. Jacobson

المصدر: PLoS Biology
PLoS Biology, Vol 17, Iss 3, p e3000161 (2019)

مصطلحات موضوعية: Lipopolysaccharides, Male, 0301 basic medicine, Adenosine, Physiology, Glycobiology, Blood Pressure, Hypothermia, Pathology and Laboratory Medicine, Biochemistry, Vascular Medicine, Body Temperature, Mice, chemistry.chemical_compound, 0302 clinical medicine, Heart Rate, Nucleic Acids, Medicine and Health Sciences, Biology (General), Mice, Knockout, biology, Adenosine transport, General Neuroscience, Nucleosides, Glycosylamines, 3. Good health, Chemistry, Phenotype, Physiological Parameters, Physical Sciences, Knockout mouse, Female, medicine.symptom, General Agricultural and Biological Sciences, Caffeine, Research Article, medicine.drug, Genotype, Receptor, Adenosine A2A, QH301-705.5, Cardiology, Adenosine kinase, Receptor, Adenosine A2B, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Signs and Symptoms, Alkaloids, Diagnostic Medicine, medicine, Extracellular, Animals, Uridine, General Immunology and Microbiology, Receptor, Adenosine A1, Receptor, Adenosine A3, Chemical Compounds, Biology and Life Sciences, Adenosine receptor, Inosine, 030104 developmental biology, chemistry, biology.protein, RNA, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d8e0168e95636d7bd632477119b585Test
https://doi.org/10.1371/journal.pbio.3000161Test

المؤلفون: Dongchun, Liang, Hui, Shao, Willi K, Born, Rebecca L, O'Brien, Henry J, Kaplan, Deming, Sun

المصدر: PLoS ONE, Vol 13, Iss 11, p e0207546 (2018)
PLoS ONE

مصطلحات موضوعية: Adenosine, Physiology, Glycobiology, lcsh:Medicine, Autoimmunity, Biochemistry, Immune Receptors, White Blood Cells, Binding Analysis, Animal Cells, Immune Physiology, Medicine and Health Sciences, lcsh:Science, Immune Response, Mice, Knockout, Innate Immune System, Immune System Proteins, Multidisciplinary, T Cells, Nucleosides, Receptors, Antigen, T-Cell, gamma-delta, Glycosylamines, Cytokines, Female, Cellular Types, Cell Binding Assay, Research Article, Signal Transduction, Cell Binding, Cell Physiology, Receptor, Adenosine A2A, Immune Cells, Immunology, Antigen-Presenting Cells, Research and Analysis Methods, Autoimmune Diseases, Uveitis, Animals, Chemical Characterization, Blood Cells, lcsh:R, Biology and Life Sciences, Proteins, Correction, Cell Biology, Molecular Development, T Cell Receptors, Mice, Inbred C57BL, Disease Models, Animal, Immune System, Th17 Cells, lcsh:Q, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccaa6eb018cdd603cb09b69896ef918Test
https://doi.org/10.1371/journal.pone.0207546Test

المؤلفون: Cao, Ruyin, Rossetti, Giulia, Bauer, Andreas, CarIoni, Paolo

المصدر: PLoS ONE, Vol 10, Iss 5, p e0126833 (2015)
PLoS one 10(5), e0126833 (2015). doi:10.1371/journal.pone.0126833
PLoS ONE

مصطلحات موضوعية: Models, Molecular, Receptor, Adenosine A2A, Science, Membranes, Artificial, Ligands, Protein Structure, Secondary, Adenosine A2 Receptor Antagonists, Cholesterol, Caffeine, Humans, Medicine, ddc:500, Research Article, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a1c36e368478a0e1126d572f5a4f3096Test
https://doaj.org/article/4429886214484ae5b78cdaa4f3503889Test

المؤلفون: Dongchun Liang, Henry J. Kaplan, Mingjiazi Chen, Deming Sun, Hui Shao, Aijun Zuo

المساهمون: Rosenbaum, James T

المصدر: PLoS ONE, Vol 9, Iss 9, p e108932 (2014)
PloS one, vol 9, iss 9
PLoS ONE
Liang, D; Zuo, A; Shao, H; Chen, M; Kaplan, HJ; & Sun, D. (2014). Roles of the adenosine receptor and CD73 in the regulatory effect of γδ T cells. PLoS ONE, 9(9). doi: 10.1371/journal.pone.0108932. UCLA: Retrieved from: http://www.escholarship.org/uc/item/64j253r0Test

مصطلحات موضوعية: Adenosine, T-Lymphocytes, Messenger, Adenosine A2A receptor, lcsh:Medicine, Autoimmunity, Inbred C57BL, Lymphocyte Activation, Interleukin 21, Mice, Animal Cells, Cytotoxic T cell, 2.1 Biological and endogenous factors, IL-2 receptor, Aetiology, lcsh:Science, Immune Response, 5'-Nucleotidase, Cells, Cultured, Multidisciplinary, Cultured, ZAP70, Cell biology, Adenosine A2 Receptor Antagonists, medicine.anatomical_structure, Cytokines, Female, Cellular Types, Dinucleoside Phosphates, Research Article, Receptor, Signal Transduction, medicine.medical_specialty, Receptor, Adenosine A2A, Adenosine A2 Receptor Agonists, General Science & Technology, T cell, Immune Cells, Cells, 1.1 Normal biological development and functioning, Immunology, Biology, Autoimmune Disease, Immunomodulation, Vaccine Related, Adenosine A2A, Underpinning research, Internal medicine, Biodefense, Phenethylamines, medicine, Animals, RNA, Messenger, Antigen-presenting cell, Cell Proliferation, Prevention, Inflammatory and immune system, lcsh:R, Immunity, Biology and Life Sciences, Cell Biology, Adenosine A3 receptor, Adenosine Monophosphate, Mice, Inbred C57BL, Endocrinology, Emerging Infectious Diseases, RNA, Clinical Immunology, lcsh:Q

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711be0c1442168392b452a97b718b2e0Test
http://europepmc.org/articles/PMC4182534?pdf=renderTest

المؤلفون: Marcelo Alarcón, Armando Rojas, Julio Caballero, Eduardo Fuentes, Iván Palomo

المصدر: PLoS ONE, Vol 9, Iss 3, p e90699 (2014)
PLoS ONE

مصطلحات موضوعية: Models, Molecular, Platelet Aggregation, Adenosine A2A receptor, Cell Communication, Pharmacology, Biochemistry, Biophysics Simulations, Mice, chemistry.chemical_compound, Adenosine Triphosphate, Drug Discovery, Biochemical Simulations, Cyclic AMP, Leukocytes, Platelet, Biochemistry Simulations, Multidisciplinary, Triazines, Hematology, Platelet Glycoprotein GPIIb-IIIa Complex, P-Selectin, Medicine, Biophysic Al Simulations, Arachidonic acid, Collagen, Chlorogenic Acid, Inflammation Mediators, Research Article, Biotechnology, medicine.drug, Platelets, Bleeding Time, Receptor, Adenosine A2A, Cell Survival, Science, Biophysics, Cell Line, Platelet Adhesiveness, Chlorogenic acid, Platelet adhesiveness, medicine, Animals, Humans, Platelet activation, Biology, Nutrition, Binding Sites, Adenine, Computational Biology, Thrombosis, Triazoles, Platelet Activation, Cyclic AMP-Dependent Protein Kinases, Adenosine, Enzyme Activation, chemistry, Hemorheology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca49d548e9c3b11f887e643b73085fdTest
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24598787/?tool=EBITest

المؤلفون: Xin Wang, Gang Pei, Yue Zhou, Ming Chen, Xiaohang Li, Jian Zhao, Wenjuan Yang, Jing Lu, Jin Cui

المصدر: PLoS ONE, Vol 11, Iss 11, p e0166415 (2016)
PLoS ONE

مصطلحات موضوعية: 0301 basic medicine, lcsh:Medicine, Adenosine A2A receptor, Biochemistry, Fluorophotometry, Amyloid beta-Protein Precursor, Mice, chemistry.chemical_compound, Spectrum Analysis Techniques, 0302 clinical medicine, Cell Signaling, Fluorescence Resonance Energy Transfer, Medicine and Health Sciences, Amyloid precursor protein, Small interfering RNAs, Drug Interactions, lcsh:Science, beta-Arrestins, Cerebral Cortex, Neurons, Gene knockdown, Multidisciplinary, biology, Neurodegenerative Diseases, Adenosine A2 Receptor Antagonists, Cell biology, Nucleic acids, Neuroprotective Agents, Neurology, Spectrophotometry, Signal transduction, Research Article, Signal Transduction, Transmembrane Receptors, Receptor, Adenosine A2A, Yellow Fluorescent Protein, Primary Cell Culture, Mice, Transgenic, Endosomes, Research and Analysis Methods, Transfection, Presenilin, Cell Line, 03 medical and health sciences, Alzheimer Disease, Mental Health and Psychiatry, mental disorders, Genetics, Presenilin-1, Animals, Humans, Non-coding RNA, Molecular Biology Techniques, Molecular Biology, Pharmacology, Amyloid beta-Peptides, Biology and life sciences, Beta-Arrestins, lcsh:R, Proteins, Correction, Cell Biology, Istradefylline, Molecular biology, Peptide Fragments, Gene regulation, Luminescent Proteins, G-Protein Signaling, 030104 developmental biology, Gene Expression Regulation, chemistry, Purines, biology.protein, RNA, Dementia, lcsh:Q, Gene expression, Amyloid Precursor Protein Secretases, G Protein Coupled Receptors, Amyloid precursor protein secretase, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::374e952597b9c01d6a3c81ca70d8da74Test
https://doi.org/10.1371/journal.pone.0166415Test

المؤلفون: Horst Vogel, Michael Werner, Joachim Piguet, Luigino Grasso, Ghérici Hassaine, Romain Wyss, Ruud Hovius

المساهمون: University of Zurich, Vogel, Horst

المصدر: PLoS ONE, Vol 8, Iss 8, p e70929 (2013)
PLOS ONE
PLoS ONE

مصطلحات موضوعية: Optical Tweezers, lcsh:Medicine, Biochemistry, 01 natural sciences, Diffusion, Single-cell analysis, SX00 SystemsX.ch, Molecular Cell Biology, Signaling in Cellular Processes, Membrane Receptor Signaling, Biomacromolecule-Ligand Interactions, Receptor, lcsh:Science, 0303 health sciences, Arrestin, Multidisciplinary, Chemistry, Vesicle, Receptors, Neurokinin-1, Cell biology, Protein Transport, Cytochemistry, SX03 CINA, Single-Cell Analysis, Transmembrane Signaling, Signal Transduction, Research Article, Biotechnology, Cell signaling, Receptor, Adenosine A2A, Biophysics, 1100 General Agricultural and Biological Sciences, 010402 general chemistry, 03 medical and health sciences, Cell surface receptor, 1300 General Biochemistry, Genetics and Molecular Biology, Humans, Biology, 030304 developmental biology, G protein-coupled receptor, 1000 Multidisciplinary, Cell Membrane, lcsh:R, Membrane Proteins, Proteins, Receptor-mediated endocytosis, 0104 chemical sciences, Transmembrane Proteins, G-Protein Signaling, HEK293 Cells, Microscopy, Fluorescence, 570 Life sciences, biology, lcsh:Q

وصف الملف: grasso.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c942437fd4a6162ee89eb4aa21ae9eTest
http://europepmc.org/articles/PMC3733713?pdf=renderTest