نتائج البحث - "MOLECULAR pathology"

1

Oncogenic driver mutations in Swiss never smoker patients with lung adenocarcinoma and correlation with clinicopathologic characteristics and outcome

المؤلفون: Claudia Grosse, Alexandra Grosse, Markus Rechsteiner, Alex Soltermann

المساهمون: University of Zurich, Grosse, Claudia

المصدر: PLoS ONE, Vol 14, Iss 8, p e0220691 (2019)
PLoS ONE

مصطلحات موضوعية: Male, 0301 basic medicine, Lung Neoplasms, Cancer Treatment, medicine.disease_cause, Gastroenterology, Lung and Intrathoracic Tumors, 0302 clinical medicine, Adenocarcinomas, Medicine and Health Sciences, Electronic Health Records, Stage (cooking), Neurological Tumors, Aged, 80 and over, Multidisciplinary, Adenocarcinoma of the Lung, Incidence (epidemiology), Middle Aged, Treatment Outcome, Oncology, Neurology, 030220 oncology & carcinogenesis, Adenocarcinoma, Medicine, Female, KRAS, Switzerland, Research Article, Adult, medicine.medical_specialty, Science, Adenocarcinoma of Lung, 610 Medicine & health, 1100 General Agricultural and Biological Sciences, Carcinomas, 03 medical and health sciences, Diagnostic Medicine, 1300 General Biochemistry, Genetics and Molecular Biology, Internal medicine, 10049 Institute of Pathology and Molecular Pathology, Genetics, Cancer Detection and Diagnosis, Adenocarcinoma of the lung, medicine, ROS1, Humans, Point Mutation, Lung cancer, Aged, Retrospective Studies, 1000 Multidisciplinary, business.industry, Biology and Life Sciences, Cancers and Neoplasms, Non-Smokers, medicine.disease, Survival Analysis, Non-Small Cell Lung Cancer, 030104 developmental biology, Mutation, Brain Metastasis, business, Brain metastasis

وصف الملف: Grosse_PlosOne_2019.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ffc10f8b92705d3f2ed56ca4efd856Test
https://doaj.org/article/d562b71d1e2f4bd682eb4290a8e377d9Test

2

Risk for molecular contamination of tissue samples evaluated for targeted anti-cancer therapy

المؤلفون: Ofer Ben-Izhak, Einav Simon, Dov Hershkovitz, Ibrahim Fahoum, Edmond Sabo, Eyal Asor, Michael Y. Stav

المصدر: PLoS ONE, Vol 12, Iss 3, p e0173760 (2017)
PLoS ONE

مصطلحات موضوعية: 0301 basic medicine, Mutation rate, Lung Neoplasms, Tissue Fixation, Cancer Treatment, lcsh:Medicine, Artificial Gene Amplification and Extension, Pathology and Laboratory Medicine, medicine.disease_cause, Polymerase Chain Reaction, law.invention, Exon, 0302 clinical medicine, Mutation Rate, Limit of Detection, law, Medicine and Health Sciences, Molecular Targeted Therapy, EGFR Exon 21 Mutation, Pathology, Molecular, lcsh:Science, DNA extraction, Polymerase chain reaction, Mutation, Paraffin Embedding, Multidisciplinary, Exons, Laboratory Equipment, ErbB Receptors, Deletion Mutation, Oncology, 030220 oncology & carcinogenesis, Engineering and Technology, Molecular Pathology, Research Article, Equipment, Adenocarcinoma of Lung, Adenocarcinoma, Research and Analysis Methods, Deep sequencing, 03 medical and health sciences, Extraction techniques, Genetics, medicine, Point Mutation, Humans, Microtomes, Molecular Biology Techniques, Molecular Biology, business.industry, Point mutation, lcsh:R, Biology and Life Sciences, Molecular biology, 030104 developmental biology, lcsh:Q, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a80ace011535ac71c55a861b195d97b2Test
http://europepmc.org/articles/PMC5348008?pdf=renderTest

3

BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications

المؤلفون: Sandro Santagata, Jochen K. Lennerz, A. John Iafrate, Kathy Vernovsky, David N. Louis, Natalie Vena, Darrell R. Borger, Dora Dias-Santagata, Azra H. Ligon, Tracy T. Batchelor, Keith L. Ligon, Quynh Lam

المصدر: PLoS ONE, Vol 6, Iss 3, p e17948 (2011)
PLoS ONE

مصطلحات موضوعية: Male, Pathology, medicine.medical_treatment, DNA Mutational Analysis, lcsh:Medicine, Pediatrics, 0302 clinical medicine, Gene duplication, Phosphorylation, Child, Extracellular Signal-Regulated MAP Kinases, lcsh:Science, Neurological Tumors, Neuropathology, In Situ Hybridization, Fluorescence, Pleomorphic xanthoastrocytoma, Multidisciplinary, Molecular pathology, Astrocytoma, Glioma, Middle Aged, Immunohistochemistry, 3. Good health, Oncology, 030220 oncology & carcinogenesis, Medicine, Female, medicine.symptom, Molecular Pathology, Research Article, Adult, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Adolescent, Genotype, Molecular Sequence Data, Neurosurgery, Biology, Polymorphism, Single Nucleotide, Young Adult, 03 medical and health sciences, Diagnostic Medicine, medicine, Humans, Anaplasia, neoplasms, Base Sequence, lcsh:R, Cancers and Neoplasms, medicine.disease, Radiation therapy, Epithelioid Glioblastoma, Anatomical Pathology, Pediatric Oncology, Mutation, Cancer research, Surgery, lcsh:Q, Glioblastoma Multiforme, 030217 neurology & neurosurgery, General Pathology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b28beb59f39c9c927fa4e35961179188Test
http://europepmc.org/articles/PMC3066220?pdf=renderTest

4

Assessment of EGFR mutations in circulating tumor cell preparations from NSCLC patients by next generation sequencing: toward a real-time liquid biopsy for treatment

المؤلفون: Lara Felicioni, Armando Santoro, Giampaolo Filice, Tommaso De Pas, Lucio Crinò, Irene Centi, Paola Venturino, Sara Malatesta, Alba A. Brandes, Fiamma Buttitta, Antonio Marchetti, Antonio Chella, Franco Cuccurullo, Maela Del Grammastro

المصدر: PLoS ONE, Vol 9, Iss 8, p e103883 (2014)
PLoS ONE

مصطلحات موضوعية: Oncology, Pathology, Lung Neoplasms, Gene Expression, lcsh:Medicine, medicine.disease_cause, Pathology and Laboratory Medicine, Lung and Intrathoracic Tumors, FACTOR-RECEPTOR MUTATIONS, Circulating tumor cell, Carcinoma, Non-Small-Cell Lung, Medicine and Health Sciences, MOLECULAR CHARACTERIZATION, PROGRESSION-FREE, Erlotinib Hydrochloride, lcsh:Science, Mutation, Multidisciplinary, High-Throughput Nucleotide Sequencing, Exons, Neoplastic Cells, Circulating, DISCORDANCE, ErbB Receptors, SURVIVAL, Erlotinib, Molecular Pathology, medicine.drug, Research Article, RESISTANT PROSTATE-CANCER, medicine.medical_specialty, Clinical Pathology, Molecular Sequence Data, Antineoplastic Agents, Sensitivity and Specificity, Molecular Genetics, LUNG-CANCER, Breast cancer, Diagnostic Medicine, Internal medicine, TYROSINE KINASE INHIBITORS, medicine, Carcinoma, Biomarkers, Tumor, Genetics, Cancer Genetics, Cancer Detection and Diagnosis, BREAST-CANCER, Humans, TECHNOLOGY, Liquid biopsy, Protein Kinase Inhibitors, Clinical Genetics, Base Sequence, business.industry, Point mutation, lcsh:R, Personalized Medicine, Biology and Life Sciences, Cancers and Neoplasms, medicine.disease, Non-Small Cell Lung Cancer, Case-Control Studies, Quinazolines, lcsh:Q, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec2d0e55e71cbd31b325ae6c849437adTest
http://europepmc.org/articles/PMC4138040?pdf=renderTest

5

The molecular detection and clinical significance of ALK rearrangement in selected advanced non-small cell lung cancer: ALK expression provides insights into ALK targeted therapy

المؤلفون: Zheng Yuan, Dongmei Lin, Yutao Liu, Hua Lin, Xiaohong Han, Li Ma, Xuezhi Hao, Ningning Zhang, Yuankai Shi, Yu-Jie Zhou, Dan Li, Yan Sun, Lin Wang

المصدر: PLoS ONE, Vol 9, Iss 1, p e84501 (2014)
PLoS ONE

مصطلحات موضوعية: Male, Lung Neoplasms, Pulmonology, Pyridines, medicine.medical_treatment, Cancer Treatment, Gene Expression, lcsh:Medicine, Lung and Intrathoracic Tumors, Targeted therapy, Risk Factors, Carcinoma, Non-Small-Cell Lung, hemic and lymphatic diseases, Pathology, Anaplastic lymphoma kinase, Anaplastic Lymphoma Kinase, Molecular Targeted Therapy, lcsh:Science, Recombination, Genetic, Multidisciplinary, Cancer Risk Factors, Middle Aged, ErbB Receptors, Treatment Outcome, Oncology, Medicine, Oncology Agents, Female, Molecular Pathology, medicine.drug, Research Article, Adult, Genotype, Biology, Crizotinib, Diagnostic Medicine, medicine, Carcinoma, Cancer Detection and Diagnosis, Humans, Clinical significance, Lung cancer, Protein Kinase Inhibitors, Aged, Neoplasm Staging, lcsh:R, Cancers and Neoplasms, Receptor Protein-Tyrosine Kinases, medicine.disease, Non-Small Cell Lung Cancer, Radiation therapy, Clinical trial, Mutation, Cancer research, Pyrazoles, lcsh:Q, General Pathology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa6928a9933d7d66f3e513da050534bTest
http://europepmc.org/articles/PMC3880316?pdf=renderTest

6

Genetic heterogeneity in a large cohort of Indian type 3 von Willebrand disease patients

المؤلفون: Shrimati Shetty, Priyanka Kasatkar, Kanjaksha Ghosh

المصدر: PLoS ONE, Vol 9, Iss 3, p e92575 (2014)
PLoS ONE

مصطلحات موضوعية: Male, lcsh:Medicine, Pathology and Laboratory Medicine, Severity of Illness Index, Cohort Studies, Isoantibodies, hemic and lymphatic diseases, Gene duplication, Molecular Cell Biology, Missense mutation, Child, lcsh:Science, Sequence Deletion, Genetics, education.field_of_study, Multidisciplinary, Molecular pathology, Hematology, Exons, Blood coagulation, Phenotype, Research Design, Codon, Nonsense, Coagulation disorders, Child, Preschool, Female, von Willebrand disease, Research Article, Adult, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, Clinical Research Design, Population, Nonsense mutation, Gene Conversion, Mutation, Missense, India, Hemorrhage, von Willebrand Disease, Type 3, Research and Analysis Methods, Genetic Heterogeneity, Young Adult, Diagnostic Medicine, von Willebrand Factor, Von Willebrand disease, medicine, Humans, Multiplex ligation-dependent probe amplification, education, Genetic Association Studies, Medicine and health sciences, Evolutionary Biology, Genetic heterogeneity, business.industry, lcsh:R, Biology and Life Sciences, Cell Biology, medicine.disease, Coagulation factor deficiencies, Haplotypes, Mutation, lcsh:Q, business, Population Genetics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e13daf97b70b4470b59e2adb4f4f07Test
http://europepmc.org/articles/PMC3967998?pdf=renderTest

7

Integrated genotypic analysis of hedgehog-related genes identifies subgroups of keratocystic odontogenic tumor with distinct clinicopathological features

المؤلفون: Kei Sakamoto, Ken-ichi Katsube, Yuji Kabasawa, Yasuyuki Shimada, Kei-ichi Morita, Ken Omura, Akira Yamaguchi

المصدر: PLoS ONE, Vol 8, Iss 8, p e70995 (2013)
PLoS ONE

مصطلحات موضوعية: Male, Pathology, Loss of Heterozygosity, lcsh:Medicine, Odontogenic Tumors, Gene mutation, Loss of heterozygosity, Oral Diseases, Child, lcsh:Science, Aged, 80 and over, Multidisciplinary, Nuclear Proteins, Middle Aged, Immunohistochemistry, Jaw Neoplasms, Head and Neck Tumors, Patched-1 Receptor, Oncology, Medicine, Female, Keratocystic Odontogenic Tumor, Immunohistochemical Analysis, Molecular Pathology, Signal Transduction, Research Article, Adult, Patched Receptors, medicine.medical_specialty, Histology, Clinical Pathology, Adolescent, Genotype, Oral Medicine, Kruppel-Like Transcription Factors, Receptors, Cell Surface, Zinc Finger Protein Gli2, Biology, Patched-2 Receptor, Molecular Genetics, Young Adult, Germline mutation, Genetic Mutation, Diagnostic Medicine, GLI2, Genetics, medicine, Humans, Hedgehog Proteins, Hedgehog, Genetic Association Studies, Aged, lcsh:R, Cancers and Neoplasms, Human Genetics, Repressor Proteins, PTCH1, Dentistry, Mutation, Odontogenic Cysts, Immunologic Techniques, Clinical Immunology, lcsh:Q, General Pathology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8808cdf966f1607efe83805690b67f31Test
http://europepmc.org/articles/PMC3737235?pdf=renderTest

8

A novel fully automated molecular diagnostic system (AMDS) for colorectal cancer mutation detection

المؤلفون: Masahiko Amano, Mami Yamashita, Shiro Kitano, Jamie Myers, Yusuke Tsukahara, Wanqing Liu, Junko Nakamura, Mark J. Ratain, Akio Yamane, Masato Nakayama, Hiroshi Ushida

المصدر: PLoS ONE, Vol 8, Iss 5, p e62989 (2013)
PLoS ONE

مصطلحات موضوعية: Oncology, Tissue Fixation, endocrine system diseases, Colorectal cancer, DNA Mutational Analysis, lcsh:Medicine, medicine.disease_cause, Bioinformatics, Polymerase Chain Reaction, Phosphatidylinositol 3-Kinases, Pathology, Frozen Sections, Pathology, Molecular, lcsh:Science, Mutation, Multidisciplinary, Paraffin Embedding, Cetuximab, Genomics, Medicine, KRAS, Colorectal Neoplasms, Molecular Pathology, medicine.drug, Research Article, Test Evaluation, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Clinical Pathology, Class I Phosphatidylinositol 3-Kinases, Point-of-care testing, Biology, Sensitivity and Specificity, Molecular Genetics, Rectal Cancer, Diagnostic Medicine, Internal medicine, Formaldehyde, Gastrointestinal Tumors, medicine, Genetics, Cancer Genetics, Panitumumab, Humans, Genetic Testing, neoplasms, Clinical Genetics, Point mutation, lcsh:R, Personalized Medicine, Reproducibility of Results, Cancers and Neoplasms, Human Genetics, medicine.disease, digestive system diseases, Mutation testing, ras Proteins, lcsh:Q, Pharmacogenomics, General Pathology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0bd89362657b4a30fcb583fc2add92Test
http://europepmc.org/articles/PMC3650034?pdf=renderTest

9

PrP(ST), a soluble, protease resistant and truncated PrP form features in the pathogenesis of a genetic prion disease

المؤلفون: Michal Mizrahi, Orli Binyamin, Kati Frid, Yael Friedman-Levi, Ruth Gabizon

المصدر: PLoS ONE, Vol 8, Iss 7, p e69583 (2013)
PLoS ONE

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c730815438015fbf4d4f8749d767bf36Test
http://europepmc.org/articles/PMC3724911?pdf=renderTest

10

Differentiating inbred mouse strains from each other and those with single gene mutations using hair proteomics

المؤلفون: John P. Sundberg, David M. Rocke, Brett S. Phinney, Robert H. Rice, Katie M. Bradshaw, Blythe Durbin-Johnson, Richard A. Eigenheer

المساهمون: Dalby, Andrew R

المصدر: PLoS ONE, Vol 7, Iss 12, p e51956 (2012)
PloS one, vol 7, iss 12
PLoS ONE

مصطلحات موضوعية: Proteomics, Mouse, Proteome, Mutant, Inbred Strains, lcsh:Medicine, Dermatologic Pathology, medicine.disease_cause, Mice, 0302 clinical medicine, Pathology, lcsh:Science, Genetics, 0303 health sciences, Mutation, Spectrometric Identification of Proteins, Multidisciplinary, integumentary system, Animal Models, Phenotype, Hair disease, 030220 oncology & carcinogenesis, Medicine, Molecular Pathology, Veterinary Pathology, Research Article, Biotechnology, General Science & Technology, Mice, Inbred Strains, Dermatology, Hair and Nail Diseases, Biology, 03 medical and health sciences, Model Organisms, Diagnostic Medicine, medicine, Animals, Gene, 030304 developmental biology, Proteomic Profiling, Human Genome, lcsh:R, medicine.disease, Veterinary Science, lcsh:Q, sense organs, Hair Diseases, Transcriptome, Protein Abundance, General Pathology, Hair

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6811979aeaab3850105b8213fd664d77Test
http://europepmc.org/articles/PMC3522583?pdf=renderTest

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