نتائج البحث

1

Immunoprofiling of fresh HAM/TSP blood samples shows altered innate cell responsiveness

المؤلفون: Omran Allatif, Noemia Mie Orii, Hélène Dutartre, Nicolas Futsch, Augusto César Penalva de Oliveira, Jorge Casseb, Brenda Rocamonde, Renaud Mahieux

المصدر: PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009940 (2021)
PLoS Neglected Tropical Diseases

مصطلحات موضوعية: Male, RNA viruses, Physiology, Cell, RC955-962, Stimulation, NK cells, Pathology and Laboratory Medicine, Monocytes, Cohort Studies, Blood cell, White Blood Cells, Medical Conditions, Animal Cells, immune system diseases, Immune Physiology, hemic and lymphatic diseases, Arctic medicine. Tropical medicine, Tropical spastic paraparesis, Medicine and Health Sciences, Receptor, Immune Response, Human T-lymphotropic virus 1, Innate Immune System, T Cells, virus diseases, Middle Aged, Interleukin-12, Paraparesis, Tropical Spastic, Killer Cells, Natural, Leukemia, Infectious Diseases, medicine.anatomical_structure, Medical Microbiology, Viral Pathogens, Viruses, Cytokines, Female, Cellular Types, Pathogens, Public aspects of medicine, RA1-1270, Brazil, Research Article, Adult, endocrine system, Immune Cells, Inflammatory Diseases, Immunology, Antigen-Presenting Cells, Microbiology, Immune system, Retroviruses, medicine, Humans, Microbial Pathogens, Blood Cells, business.industry, Organisms, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Dendritic Cells, Cell Biology, Htlv-1, Molecular Development, medicine.disease, Immunity, Innate, Immune System, business, Asymptomatic carrier, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886b909f437b8959872deb69e7742a92Test
https://doaj.org/article/db81415417f94efdb20bd8811409b193Test

2

Comparative analysis of the ex vivo IFN-gamma responses to CD8+ T cell epitopes within allelic forms of PfAMA1 in subjects with natural exposure to malaria

المؤلفون: Ebenezer Addo Ofori, Maria Belmonte, Bjoern Peters, Martha Sedegah, Eileen Villasante, Harini Ganeshan, Omarine Nfor Nlinwe, Kwadwo Akyea-Mensah, Eric Kyei-Baafour, Kwadwo A. Kusi

المصدر: PLoS ONE, Vol 16, Iss 9, p e0257219 (2021)
PLoS ONE

مصطلحات موضوعية: Male, Protozoan Proteins, Epitopes, T-Lymphocyte, CD8-Positive T-Lymphocytes, Biochemistry, Epitope, White Blood Cells, Medical Conditions, Animal Cells, Medicine and Health Sciences, Cytotoxic T cell, Public and Occupational Health, Malaria, Falciparum, Amino Acids, Enzyme-Linked Immunoassays, Immune Response, Protozoans, Multidisciplinary, Organic Compounds, T Cells, ELISPOT, Malarial Parasites, Eukaryota, Middle Aged, Vaccination and Immunization, Chemistry, medicine.anatomical_structure, Physical Sciences, Medicine, Female, Cellular Types, Research Article, Adult, Immune Cells, T cell, Science, Plasmodium falciparum, Immunology, Antigens, Protozoan, Human leukocyte antigen, Biology, Research and Analysis Methods, Young Adult, Antigen, Malaria Vaccines, Vaccine Development, Parasitic Diseases, medicine, Humans, Apical membrane antigen 1, Immunoassays, Alleles, Blood Cells, Organic Chemistry, T-cell receptor, Organisms, Chemical Compounds, Biology and Life Sciences, Proteins, Cell Biology, Tropical Diseases, Parasitic Protozoans, Malaria, Amino Acid Substitution, Immunologic Techniques, Preventive Medicine, Peptides

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feae6d60d5975971023cc32f97d35aaeTest
https://doaj.org/article/584a3bd4a35d4faaa695c701e2bdbb7eTest

3

Impaired tumor immune response in metastatic tumors is a selective pressure for neutral evolution in CRC cases

المصدر: PLoS Genetics, Vol 17, Iss 1, p e1009113 (2021)
PLoS Genetics

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Colorectal cancer, Programmed Cell Death 1 Receptor, CD8-Positive T-Lymphocytes, QH426-470, Immune Receptors, Biochemistry, Metastasis, White Blood Cells, 0302 clinical medicine, Animal Cells, Basic Cancer Research, Medicine and Health Sciences, Cytotoxic T cell, Postoperative Period, Immune Response, Hepatitis A Virus Cellular Receptor 2, Genetics (clinical), Aged, 80 and over, Immune System Proteins, T Cells, Genomics, Middle Aged, Progression-Free Survival, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Female, Cellular Types, Colorectal Neoplasms, Research Article, Signal Transduction, Adenoma, Adult, Evolutionary Immunology, DNA Copy Number Variations, Immune Cells, T cell, Immunology, Receptors, Antigen, T-Cell, Biology, 03 medical and health sciences, Cancer Genomics, Genomic Medicine, Genetics, medicine, Carcinoma, Humans, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Aged, Colorectal Cancer, Evolutionary Biology, Blood Cells, Genome, Human, Genetic Drift, T-cell receptor, Immunity, Cancers and Neoplasms, Biology and Life Sciences, Proteins, Cell Biology, medicine.disease, T Cell Receptors, 030104 developmental biology, Metastatic Tumors, Cancer research, Neoplasm Recurrence, Local, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927c482c07abdf21ed1e825a726cf5d1Test
https://doi.org/10.1371/journal.pgen.1009113Test

4

Hypomethylation of IL1RN and NFKB1 genes is linked to the dysbalance in IL1β/IL-1Ra axis in female patients with type 2 diabetes mellitus

المؤلفون: Sona Margaryan, Regina Fillerova, Eva Kriegova, Veronika Smotkova Kraiczova, Gayane Manukyan

المصدر: PLoS ONE
PLoS ONE, Vol 15, Iss 5, p e0233737 (2020)

مصطلحات موضوعية: Male, 0301 basic medicine, endocrine system diseases, THP-1 Cells, Physiology, Interleukin-1beta, Pathology and Laboratory Medicine, Biochemistry, Pathogenesis, White Blood Cells, Endocrinology, 0302 clinical medicine, Animal Cells, Immune Physiology, Medicine and Health Sciences, Immune Response, Innate Immune System, DNA methylation, Multidisciplinary, Interleukin, Methylation, Middle Aged, Chromatin, Type 2 Diabetes, Nucleic acids, medicine.anatomical_structure, Medicine, Cytokines, Female, Epigenetics, Cellular Types, medicine.symptom, DNA modification, Chromatin modification, Research Article, Chromosome biology, Adult, Cell biology, medicine.medical_specialty, Endocrine Disorders, Science, Immune Cells, Inflammatory Diseases, Immunology, 030209 endocrinology & metabolism, Inflammation, 03 medical and health sciences, Signs and Symptoms, Diagnostic Medicine, Pancreatitis, Chronic, Internal medicine, Genetics, Diabetes Mellitus, medicine, Humans, Aged, Treatment Guidelines, Blood Cells, Health Care Policy, Biology and life sciences, business.industry, Macrophages, Pancreatic islets, NF-kappa B p50 Subunit, Type 2 Diabetes Mellitus, DNA, Molecular Development, Health Care, Interleukin 1 Receptor Antagonist Protein, 030104 developmental biology, Diabetes Mellitus, Type 2, Metabolic Disorders, Immune System, Gene expression, business, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e942325723b12fa556a7725bb7017cTest
https://doi.org/10.1371/journal.pone.0233737Test

5

Determination of chitinase 3-like 1 in cerebrospinal fluid in multiple sclerosis and other neurological diseases

المؤلفون: Olga Zapletalová, Pavel Hradílek, David Stejskal, Pavlína Kušnierová, David Zeman

المصدر: PLoS ONE, Vol 15, Iss 5, p e0233519 (2020)
PLoS ONE

مصطلحات موضوعية: Male, Central Nervous System, 0301 basic medicine, Pathology, Physiology, Nervous System, Biochemistry, White Blood Cells, 0302 clinical medicine, Cerebrospinal fluid, Animal Cells, Medicine and Health Sciences, Enzyme-Linked Immunoassays, Cerebrospinal Fluid, Aged, 80 and over, Multidisciplinary, Clinically isolated syndrome, biology, Neurodegenerative Diseases, Middle Aged, Prognosis, Body Fluids, medicine.anatomical_structure, Neurology, Peripheral nervous system, Medicine, Female, Anatomy, Cellular Types, Research Article, Adult, Immunofixation, medicine.medical_specialty, Multiple Sclerosis, Neurofilament, Inflammatory Diseases, Immune Cells, Science, Immunology, Research and Analysis Methods, CHI3L1, Autoimmune Diseases, Young Adult, 03 medical and health sciences, Diagnostic Medicine, medicine, Humans, Chitinase-3-Like Protein 1, Immunoassays, Neuroinflammation, Aged, Blood Cells, business.industry, Macrophages, Multiple sclerosis, Biology and Life Sciences, Cell Biology, medicine.disease, Demyelinating Disorders, 030104 developmental biology, Immunologic Techniques, biology.protein, Clinical Immunology, Clinical Medicine, business, Biomarkers, 030217 neurology & neurosurgery, Demyelinating Diseases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49242942945784015adfea13ee213f2bTest
https://doi.org/10.1371/journal.pone.0233519Test

6

Loss of intra-islet heparan sulfate is a highly sensitive marker of type 1 diabetes progression in humans

المؤلفون: Christopher R. Parish, J. Dennis Wilson, Helen E. Thomas, Fui Jiun Choong, Barbara Ludwig, Andrew F. Ziolkowski, Charmaine J. Simeonovic, Sarah K. Popp, Stefan R. Bornstein, Thomas W.H. Kay, Lora Starrs, Craig Freeman, Thomas Loudovaris, Debra J. Brown, Alberto Pugliese

المساهمون: University of Zurich, Simeonovic, Charmaine J

المصدر: PLoS ONE, Vol 13, Iss 2, p e0191360 (2018)
PLoS ONE

مصطلحات موضوعية: Male, 0301 basic medicine, endocrine system diseases, medicine.medical_treatment, 10265 Clinic for Endocrinology and Diabetology, lcsh:Medicine, Biochemistry, White Blood Cells, chemistry.chemical_compound, Endocrinology, Spectrum Analysis Techniques, 0302 clinical medicine, Animal Cells, Medicine and Health Sciences, Insulin, Child, lcsh:Science, Cells, Cultured, Staining, Multidisciplinary, geography.geographical_feature_category, Chemistry, Cell Staining, Drugs, Heparan sulfate, Flow Cytometry, Islet, 3. Good health, medicine.anatomical_structure, Spectrophotometry, Child, Preschool, Disease Progression, Female, Cytophotometry, Anatomy, Cellular Types, medicine.symptom, Beta cell, Biliary Disorders, Research Article, Adult, medicine.medical_specialty, endocrine system, Adolescent, Endocrine Disorders, Immune Cells, Immunology, Endocrine System, 030209 endocrinology & metabolism, Inflammation, 610 Medicine & health, Gastroenterology and Hepatology, 1100 General Agricultural and Biological Sciences, Research and Analysis Methods, Sensitivity and Specificity, Islets of Langerhans, Young Adult, 03 medical and health sciences, Exocrine Glands, 1300 General Biochemistry, Genetics and Molecular Biology, Internal medicine, Diabetes Mellitus, medicine, Humans, Heparanase, Pancreas, Pharmacology, Diabetic Endocrinology, geography, 1000 Multidisciplinary, Blood Cells, Heparin, Pancreatic islets, lcsh:R, Biology and Life Sciences, Infant, Cell Biology, medicine.disease, Hormones, Diabetes Mellitus, Type 1, 030104 developmental biology, Specimen Preparation and Treatment, Metabolic Disorders, Case-Control Studies, lcsh:Q, Heparitin Sulfate, Insulitis, Biomarkers

وصف الملف: pone.0191360.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b710034fc5ae324ee64bd93770d4b09fTest
http://europepmc.org/articles/PMC5802856?pdf=renderTest

7

Comprehensive mapping of antigen specific T cell responses in hepatitis C virus infected patients with or without spontaneous viral clearance

المؤلفون: Zhengkun Tu, Hongqing Yan, Chao Zhang, Xinyue Chen, Junqi Niu, Yonghong Zhang, Jin Zhong, Shasha Wang, Yuanyuan Cui, Rui Hua, Pei Hao, Xia Jin, Dongmei Li

المصدر: PLoS ONE, Vol 12, Iss 2, p e0171217 (2017)
PLoS ONE

مصطلحات موضوعية: Male, Proteomics, RNA viruses, 0301 basic medicine, Programmed Cell Death 1 Receptor, Epitopes, T-Lymphocyte, lcsh:Medicine, Hepacivirus, Lymphocyte Activation, medicine.disease_cause, Biochemistry, Epitope, White Blood Cells, Database and Informatics Methods, T-Lymphocyte Subsets, Animal Cells, Medicine and Health Sciences, Cytotoxic T cell, Enzyme-Linked Immunoassays, Peptide Libraries, lcsh:Science, Immune Response, Phylogeny, Pathology and laboratory medicine, Multidisciplinary, biology, T Cells, Hepatitis C virus, Antibodies, Monoclonal, virus diseases, Middle Aged, Viral Load, Medical microbiology, Hepatitis C, medicine.anatomical_structure, Viruses, Cytokines, Female, Cellular Types, Pathogens, Antibody, Sequence Analysis, Viral load, Research Article, Adult, Genotype, Bioinformatics, Immune Cells, T cell, Immunology, Sequence Databases, Cytotoxic T cells, Research and Analysis Methods, Antiviral Agents, Peptide Mapping, Microbiology, Young Adult, 03 medical and health sciences, Immune system, medicine, Humans, Immunoassays, Aged, Blood Cells, Flaviviruses, business.industry, lcsh:R, Organisms, Viral pathogens, Biology and Life Sciences, Cell Biology, Virology, Hepatitis viruses, digestive system diseases, Microbial pathogens, Patient Outcome Assessment, Biological Databases, 030104 developmental biology, Epitope mapping, Immunologic Techniques, biology.protein, lcsh:Q, Peptides, business, Epitope Mapping

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6920b57133b679317892f68d4f64220Test
http://europepmc.org/articles/PMC5295680?pdf=renderTest

8

Safety and Reproducibility of a Clinical Trial System Using Induced Blood Stage Plasmodium vivax Infection and its Potential as a Model to Evaluate Malaria Transmission

المؤلفون: James S. McCarthy, Denise L. Doolan, Julie G. Burel, Simon H. Apte

المصدر: PLoS Neglected Tropical Diseases, Vol 10, Iss 12, p e0005031 (2016)
PLoS Neglected Tropical Diseases

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Cytotoxicity, Immunologic, Male, 0301 basic medicine, Plasmodium, Erythrocytes, Reticulocytes, Plasmodium vivax, Genes, MHC Class I, CD8-Positive T-Lymphocytes, Lymphocyte Activation, Parasitemia, White Blood Cells, Interleukin 21, 0302 clinical medicine, Animal Cells, Red Blood Cells, Medicine and Health Sciences, Cytotoxic T cell, Malaria, Falciparum, Immune Response, Protozoans, Antigen Presentation, Immunity, Cellular, biology, T Cells, lcsh:Public aspects of medicine, Malarial Parasites, Healthy Volunteers, 3. Good health, Infectious Diseases, medicine.anatomical_structure, Female, Cellular Types, Research Article, Adult, lcsh:Arctic medicine. Tropical medicine, lcsh:RC955-962, Immune Cells, T cell, Plasmodium falciparum, Immunology, 030231 tropical medicine, Antigen presentation, Cytotoxic T cells, 03 medical and health sciences, Immune system, Antigen, Parasite Groups, parasitic diseases, Malaria, Vivax, Parasitic Diseases, medicine, Humans, Blood Cells, Organisms, Public Health, Environmental and Occupational Health, Biology and Life Sciences, lcsh:RA1-1270, Cell Biology, biology.organism_classification, ADP-ribosyl Cyclase 1, Virology, Parasitic Protozoans, 030104 developmental biology, Parasitology, Apicomplexa, CD8, T-Lymphocytes, Cytotoxic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803130857c11aaf99feb9bc00eb65728Test
http://europepmc.org/articles/PMC5145136?pdf=renderTest

9

CD8+ T cells retain protective functions despite sustained inhibitory receptor expression during Epstein-Barr virus infection in vivo

المؤلفون: Riccarda Capaul, Johannes H. Dreyer, Hana Zdimerova, Anne Müller, Bithi Chatterjee, Yun Deng, Andrea Zbinden, Olga Antsiferova, Nicolás Gonzalo Núñez, Mark D. Robinson, Christian Münz, Tarik Azzi, Liliana D. Vanoaica, David Nadal, Hans J. Stauss, Burkhard Becher, Angelika Holler

المساهمون: University of Zurich, Münz, Christian

المصدر: PLoS Pathogens
PLoS Pathogens, Vol 15, Iss 5, p e1007748 (2019)

مصطلحات موضوعية: 10028 Institute of Medical Virology, Epstein-Barr Virus Infections, Herpesvirus 4, Human, Physiology, Receptor expression, Programmed Cell Death 1 Receptor, 2405 Parasitology, Mice, SCID, CD8-Positive T-Lymphocytes, 10263 Institute of Experimental Immunology, medicine.disease_cause, Immune Receptors, Biochemistry, White Blood Cells, Mice, Animal Cells, Mice, Inbred NOD, Immune Physiology, Medicine and Health Sciences, Cytotoxic T cell, Biology (General), Pathology and laboratory medicine, Innate Immune System, 0303 health sciences, Immune System Proteins, T Cells, 2404 Microbiology, 030302 biochemistry & molecular biology, Cell Differentiation, Medical microbiology, Viral Load, 10124 Institute of Molecular Life Sciences, 3. Good health, medicine.anatomical_structure, Viruses, Cytokines, Cellular Types, Pathogens, Inflammation Mediators, Coreceptors, Research Article, Signal Transduction, Adult, Herpesviruses, QH301-705.5, Immune Cells, T cell, Immunology, Cytotoxic T cells, 610 Medicine & health, Biology, Microbiology, Virus, 03 medical and health sciences, Immune system, 1311 Genetics, Virology, 1312 Molecular Biology, Genetics, medicine, Epstein-Barr virus, Animals, Humans, Molecular Biology, 030304 developmental biology, 2403 Immunology, Blood Cells, Gene Expression Profiling, Organisms, Viral pathogens, Biology and Life Sciences, Proteins, Germinal center, CD coreceptors, Cell Biology, RC581-607, Molecular Development, Epstein–Barr virus, Microbial pathogens, T Cell Receptors, Immune System, Case-Control Studies, 2406 Virology, 570 Life sciences, biology, Parasitology, Immunologic diseases. Allergy, DNA viruses, Viral Transmission and Infection, CD8, Developmental Biology, T-Lymphocytes, Cytotoxic

وصف الملف: journal.ppat.1007748.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::874c9f5ed8e6affeb62d027abadd074fTest
https://doi.org/10.1371/journal.ppat.1007748Test

10

A new biomarker candidate for spinal muscular atrophy: Identification of a peripheral blood cell population capable of monitoring the level of survival motor neuron protein

المؤلفون: Masayuki Arakawa, Noriko Otsuki, Kayoko Saito, Ryoko Aoki, Reiko Arakawa, Kaori Kaneko

المصدر: PLoS ONE, Vol 13, Iss 8, p e0201764 (2018)
PLoS ONE

مصطلحات موضوعية: Male, 0301 basic medicine, CD3 Complex, Physiology, animal diseases, Sialic Acid Binding Ig-like Lectin 3, Protein Expression, lcsh:Medicine, Biochemistry, Monocytes, White Blood Cells, Spectrum Analysis Techniques, Animal Cells, Medicine and Health Sciences, Child, lcsh:Science, Neurons, Motor Neurons, Staining, education.field_of_study, Multidisciplinary, biology, medicine.diagnostic_test, Cell Staining, Middle Aged, Flow Cytometry, SMA, Body Fluids, Survival of Motor Neuron 2 Protein, Blood, medicine.anatomical_structure, Spectrophotometry, Child, Preschool, Biomarker (medicine), Female, Cytophotometry, Cellular Types, Anatomy, Research Article, Adult, Adolescent, Imaging Techniques, Immune Cells, Antigens, CD19, Immunology, Population, Research and Analysis Methods, CD19, Flow cytometry, Muscular Atrophy, Spinal, Young Adult, 03 medical and health sciences, Fluorescence Imaging, Gene Expression and Vector Techniques, medicine, Humans, Peripheral blood cell, Molecular Biology Techniques, education, Molecular Biology, Molecular Biology Assays and Analysis Techniques, Blood Cells, business.industry, lcsh:R, Infant, Biology and Life Sciences, Cell Biology, Spinal muscular atrophy, Motor neuron, medicine.disease, Survival of Motor Neuron 1 Protein, nervous system diseases, 030104 developmental biology, nervous system, Specimen Preparation and Treatment, Cellular Neuroscience, Cancer research, biology.protein, lcsh:Q, business, Biomarkers, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce408e7d4198ac73e2627f8ecf144c1Test
https://doi.org/10.1371/journal.pone.0201764Test

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