Short Report: Asymptomatic Zika virus infections with low viral loads not likely to establish transmission in New Orleans Aedes populations
| العنوان: | Short Report: Asymptomatic Zika virus infections with low viral loads not likely to establish transmission in New Orleans Aedes populations |
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| المؤلفون: | Christine E S Walsh, Matthew J Ward, Rebecca C. Christofferson, Joshua Yukich, Brendan H Carter, Dawn M. Wesson |
| المصدر: | PLoS ONE PLoS ONE, Vol 15, Iss 5, p e0233309 (2020) |
| بيانات النشر: | Public Library of Science (PLoS), 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | RNA viruses, Male, 0301 basic medicine, Viral Diseases, Physiology, viruses, Disease Vectors, Pathology and Laboratory Medicine, Virus Replication, Mosquitoes, Zika virus, Serology, 0302 clinical medicine, Aedes, Medicine and Health Sciences, Multidisciplinary, Zika Virus Infection, Eukaryota, New Orleans, virus diseases, Viral Load, Body Fluids, Insects, Autochthonous Transmission, Infectious Diseases, Blood, Medical Microbiology, Viral Pathogens, Viruses, Medicine, Female, Pathogens, Viral Vectors, Anatomy, Viral load, Wolbachia, Research Article, Aedes albopictus, Post exposure, Arthropoda, Science, 030231 tropical medicine, Mosquito Vectors, Aedes aegypti, Aedes Aegypti, Biology, Microbiology, 03 medical and health sciences, Virology, Animals, Humans, Serologic Tests, Viremia, Saliva, Microbial Pathogens, Biology and life sciences, Flaviviruses, Bacteria, Extramural, fungi, Organisms, Zika Virus, biology.organism_classification, Invertebrates, Insect Vectors, Species Interactions, 030104 developmental biology, Viral Transmission and Infection |
| الوصف: | Aedes aegypti and Aedes albopictus are both vectors of Zika virus and both are endemic to the New Orleans Metropolitan area. Fortunately, to date there has been no known autochthonous transmission of Zika virus in New Orleans. No studies of the vector competence of local populations of Ae. aegypti and Ae. albopictus for Zika virus transmission have been conducted. To determine if New Orleans Ae. aegypti and Ae. albopictus mosquitoes are competent for Zika virus, mosquitoes were reared to generation F3 from eggs collected in New Orleans during the 2018 mosquito season. Adults were fed an infectious blood meal and kept for 15 days in an environmental chamber. Transmission assays were conducted at 4, 10, and 15 days post exposure and RT-PCR was run on bodies and saliva to detect the presence of Zika virus RNA. We observed remarkably low susceptibility of both Ae. aegypti and Ae. albopictus from New Orleans to a Zika strain from Panama after oral challenge. These results suggest a limited risk of Zika virus transmission should it be introduced to the New Orleans area, and may partially explain why no transmission was detected in Louisiana during the 2016 epidemic in the Americas, despite multiple known travel associated introductions to New Orleans. Despite these results these mosquito populations are known to be competent vectors for some other mosquito-borne viruses and control measures should not be relaxed. |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1a9f575bf0ca51f47096ba7d548363Test https://doi.org/10.1371/journal.pone.0233309Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....8b1a9f575bf0ca51f47096ba7d548363 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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