مورد إلكتروني
Analysis of the distribution of magnetic fluid inside tumors by a giant magnetoresistance probe
| العنوان: | Analysis of the distribution of magnetic fluid inside tumors by a giant magnetoresistance probe |
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| بيانات النشر: | Public Library of Science 2013-11-29 |
| تفاصيل مُضافة: | Gooneratne, Chinthaka P. Kurnicki, Adam Yamada, Sotoshi Mukhopadhyay, Subhas C. Kosel, Jürgen |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Magnetic fluid hyperthermia (MFH) therapy uses the magnetic component of electromagnetic fields in the radiofrequency spectrum to couple energy to magnetic nanoparticles inside tumors. In MFH therapy, magnetic fluid is injected into tumors and an alternating current (AC) magnetic flux is applied to heat the magnetic fluid- filled tumor. If the temperature can be maintained at the therapeutic threshold of 42C for 30 minutes or more, the tumor cells can be destroyed. Analyzing the distribution of the magnetic fluid injected into tumors prior to the heating step in MFH therapy is an essential criterion for homogenous heating of tumors, since a decision can then be taken on the strength and localization of the applied external AC magnetic flux density needed to destroy the tumor without affecting healthy cells. This paper proposes a methodology for analyzing the distribution of magnetic fluid in a tumor by a specifically designed giant magnetoresistance (GMR) probe prior to MFH heat treatment. Experimental results analyzing the distribution of magnetic fluid suggest that different magnetic fluid weight densities could be estimated inside a single tumor by the GMR probe. 2013 Gooneratne et al. |
| مصطلحات الفهرس: | ferucarbotran, magnetic fluid, magnetic nanoparticle, unclassified drug, alternating current, cell specificity, density, finite element analysis, giant magnetoresistance probe, hyperthermic therapy, magnetic field, magnetic fluid hyperthermia therapy, mechanical probe, statistical model, tissue distribution, tumor cell destruction, Article |
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| الإتاحة: | Open access content. Open access content http://creativecommons.org/licenses/by/3.0Test This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0Test/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Archived with thanks to PLoS ONE |
| ملاحظة: | Gooneratne CP, Kurnicki A, Yamada S, Mukhopadhyay SC, Kosel J (2013) Analysis of the Distribution of Magnetic Fluid inside Tumors by a Giant Magnetoresistance Probe. PLoS ONE 8: e81227. doi:10.1371/journal.pone.0081227. English |
| أرقام أخرى: | KAUST oai:repository.kaust.edu.sa:10754/325329 Gooneratne CP, Kurnicki A, Yamada S, Mukhopadhyay SC, Kosel J (2013) Analysis of the Distribution of Magnetic Fluid inside Tumors by a Giant Magnetoresistance Probe. PLoS ONE 8: e81227. doi:10.1371/journal.pone.0081227. 19326203 24312280 10.1371/journal.pone.0081227 PLoS ONE PMC3843682 906691927 |
| المصدر المساهم: | KING ABDULLAH UNIV OF SCI & TECH From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.ocn906691927 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |