دورية أكاديمية
Local Cattle and Badger Populations Affect the Risk of Confirmed Tuberculosis in British Cattle Herds
| العنوان: | Local Cattle and Badger Populations Affect the Risk of Confirmed Tuberculosis in British Cattle Herds |
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| المؤلفون: | Vial, F, Johnston, WT, Donnelly, CA |
| المساهمون: | Medical Research Council (MRC) |
| بيانات النشر: | Public Library of Science |
| سنة النشر: | 2011 |
| المجموعة: | Imperial College London: Spiral |
| مصطلحات موضوعية: | Science & Technology, Multidisciplinary Sciences, Science & Technology - Other Topics, MYCOBACTERIUM-BOVIS INFECTIONS, REPUBLIC-OF-IRELAND, HUSBANDRY PRACTICES, WILD BOAR, ENGLAND, ASSOCIATION, BREAKDOWNS, FARMS, EPIDEMIOLOGY, STRATEGIES, Animals, Cattle, Health Surveys, Immunity, Herd, Models, Biological, Multivariate Analysis, Mustelidae, Population Dynamics, Reproducibility of Results, Risk Factors, Time Factors, Tuberculosis, Bovine, United Kingdom, Great Britain |
| الوصف: | Background: The control of bovine tuberculosis (bTB) remains a priority on the public health agenda in Great Britain, after launching in 1998 the Randomised Badger Culling Trial (RBCT) to evaluate the effectiveness of badger (Meles meles) culling as a control strategy. Our study complements previous analyses of the RBCT data (focusing on treatment effects) by presenting analyses of herd-level risks factors associated with the probability of a confirmed bTB breakdown in herds within each treatment: repeated widespread proactive culling, localized reactive culling and no culling (survey-only). Methodology/Principal Findings: New cases of bTB breakdowns were monitored inside the RBCT areas from the end of the first proactive badger cull to one year after the last proactive cull. The risk of a herd bTB breakdown was modeled using logistic regression and proportional hazard models adjusting for local farm-level risk factors. Inside survey-only and reactive areas, increased numbers of active badger setts and cattle herds within 1500 m of a farm were associated with an increased bTB risk. Inside proactive areas, the number of M. bovis positive badgers initially culled within 1500 m of a farm was the strongest predictor of the risk of a confirmed bTB breakdown. Conclusions/Significance: The use of herd-based models provide insights into how local cattle and badger populations affect the bTB breakdown risks of individual cattle herds in the absence of and in the presence of badger culling. These measures of local bTB risks could be integrated into a risk-based herd testing programme to improve the targeting of interventions aimed at reducing the risks of bTB transmission. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1932-6203 |
| العلاقة: | PLOS One; http://hdl.handle.net/10044/1/48844Test; https://dx.doi.org/10.1371/journal.pone.0018058Test; G0600719B |
| DOI: | 10.1371/journal.pone.0018058 |
| الإتاحة: | https://doi.org/10.1371/journal.pone.0018058Test http://hdl.handle.net/10044/1/48844Test |
| حقوق: | © 2011 Vial et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0Test/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
| رقم الانضمام: | edsbas.44B698FC |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 19326203 |
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| DOI: | 10.1371/journal.pone.0018058 |