دورية أكاديمية
“Acute kidney injury in critically ill patients with COVID–19: The AKICOV multicenter study in Catalonia”
| العنوان: | “Acute kidney injury in critically ill patients with COVID–19: The AKICOV multicenter study in Catalonia” |
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| المؤلفون: | de la Vega Sánchez, Arsenio, Navas Pérez, Ana Maria, Torrens Sonet, María, Ortiz Ballujera, Patricia, Vendrell Torra, Ester, Pérez Carrasco, Marcos, Diaz Buendia, YOLANDA |
| المساهمون: | de la Vega Sánchez A, Pérez-Carrasco M Intensive Care Department, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Shock, Organ Dysfunction and Resuscitation Research Group, Universitat Autònoma de Barcelona, Vall d’Hebron Research Institute (VHIR), Barcelona, Spain. Navas Pérez A Critical Care Center, Parc Tauli Hospital Universitari, Institut d’Investigació i Innovació Parc Taulí I3PT, Universitat Autònoma de Barcelona, Sabadell, Barcelona, Spain. Torrens Sonet M Intensive Care Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. Diaz Buendia Y Critical Care Department, Hospital del Mar, Barcelona, Spain. Ortiz Ballujera P Intensive Care Department, Hospital Universitari Doctor Josep Trueta de Girona, Girona, Spain. Vendrell Torra E Intensive Care Department, Hospital General de Granollers, Granollers, Spain, Hospital General de Granollers |
| المصدر: | Scientia |
| بيانات النشر: | Public Library of Science |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | COVID-19 (Malaltia) - Complicacions, Ronyons - Malalties - Prognosi, Insuficiència renal aguda - Prognosi, DISEASES::Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections, DISEASES::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases::Renal Insufficiency::Acute Kidney Injury, PUBLICATION CHARACTERISTICS::Study Characteristics::Multicenter Study, ENFERMEDADES::virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus, ENFERMEDADES::enfermedades urogenitales masculinas::enfermedades urológicas::enfermedades renales::insuficiencia renal::lesión renal aguda, CARACTERÍSTICAS DE PUBLICACIONES::características del estudio::estudio multicéntrico |
| الوصف: | Lesió renal aguda; COVID-19; Catalunya ; Acute kidney injury; COVID-19; Catalonia ; Lesión renal aguda; COVID-19; Cataluña ; This study describes the incidence, evolution and prognosis of acute kidney injury (AKI) in critical COVID-19 during the first pandemic wave. We performed a prospective, observational, multicenter study of confirmed COVID-19 patients admitted to 19 intensive care units (ICUs) in Catalonia (Spain). Data regarding demographics, comorbidities, drug and medical treatment, physiological and laboratory results, AKI development, need for renal replacement therapy (RRT) and clinical outcomes were collected. Descriptive statistics and logistic regression analysis for AKI development and mortality were used. A total of 1,642 patients were enrolled (mean age 63 (15.95) years, 67.5% male). Mechanical ventilation (MV) was required for 80.8% and 64.4% of these patients, who were in prone position, while 67.7% received vasopressors. AKI at ICU admission was 28.4% and increased to 40.1% during ICU stay. A total of 172 (10.9%) patients required RRT, which represents 27.8% of the patients who developed AKI. AKI was more frequent in severe acute respiratory distress syndrome (ARDS) ARDS patients (68% vs 53.6%, p<0.001) and in MV patients (91.9% vs 77.7%, p<0.001), who required the prone position more frequently (74.8 vs 61%, p<0.001) and developed more infections. ICU and hospital mortality were increased in AKI patients (48.2% vs 17.7% and 51.1% vs 19%, p <0.001) respectively). AKI was an independent factor associated with mortality (IC 1.587-3.190). Mortality was higher in AKI patients who required RRT (55.8% vs 48.2%, p <0.04). Conclusions There is a high incidence of AKI in critically ill patients with COVID-19 disease and it is associated with higher mortality, increased organ failure, nosocomial infections and prolonged ICU stay. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | PloS one;18(4); https://doi.org/10.1371/journal.pone.0284248Test; de la Vega Sánchez A, Navas Pérez A, Pérez-Carrasco M, Torrens Sonet M, Diaz Buendia Y, Ortiz Ballujera P, et al. "Acute kidney injury in critically ill patients with COVID-19: The AKICOV multicenter study in Catalonia". PLoS One. 2023 Apr 14;18(4):e0284248.; https://hdl.handle.net/11351/10903Test |
| DOI: | 10.1371/journal.pone.0284248 |
| الإتاحة: | https://doi.org/10.1371/journal.pone.0284248Test https://hdl.handle.net/11351/10903Test |
| حقوق: | Attribution 4.0 International ; http://creativecommons.org/licenses/by/4.0Test/ ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.1B08BD6C |
| قاعدة البيانات: | BASE |
| DOI: | 10.1371/journal.pone.0284248 |
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