Genome and Bioinformatic Analysis of a HAdV-B14p1 Virus Isolated from a Baby with Pneumonia in Beijing, China
| العنوان: | Genome and Bioinformatic Analysis of a HAdV-B14p1 Virus Isolated from a Baby with Pneumonia in Beijing, China |
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| المؤلفون: | Yixin Ji, Wenbo Xu, Junjing An, Zhengde Xie, Donald Seto, Liuying Tang, Shoaleh Dehghan |
| المصدر: | PLoS ONE PLoS ONE, Vol 8, Iss 3, p e60345 (2013) |
| بيانات النشر: | Public Library of Science, 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | Viral Diseases, Epidemiology, lcsh:Medicine, Genome, Adenovirus Infections, Human, Emerging Viral Diseases, Nucleic Acids, Molecular Cell Biology, Pathology, lcsh:Science, Phylogeny, Genetics, Molecular Epidemiology, Multidisciplinary, Adenovirus genome, virus diseases, Genome project, General Medicine, Infectious Diseases, GenBank, Genetic Epidemiology, Medicine, Public Health, General Agricultural and Biological Sciences, Research Article, China, Clinical Pathology, Infectious Disease Control, Sequence analysis, Genomics, Genome, Viral, Biology, Microbiology, Virus, General Biochemistry, Genetics and Molecular Biology, Molecular Genetics, Diagnostic Medicine, Virology, Humans, Microbial Pathogens, Adenoviruses, Human, lcsh:R, Outbreak, Computational Biology, Infant, DNA, Pneumonia, Sequence Analysis, DNA, Clinical Microbiology, Emerging Infectious Diseases, DNA, Viral, lcsh:Q, Preventive Medicine |
| الوصف: | The genome of HAdV-B14p1 strain BJ430, isolated from a six-month-old baby diagnosed with bronchial pneumonia at the Beijing Children’s Hospital in December 2010, was sequenced, analyzed, and compared with reference adenovirus genome sequences archived in GenBank. This genome is 34,762 bp in length, remarkably presenting 99.9% identity with the genome from HAdV14p1 strain 303600, which was isolated in the USA (2006). Even more remarkable, it is 99.7% identical with the HAdV-B14p (prototype “de Wit” strain) genome, isolated from The Netherlands in 1955. The patient and its parents presumably had no or limited contact with persons from the USA and Ireland, both of which reported outbreaks of the re-emergent virus HAdV-14p1 recently. These genome data, its analysis, and this report provide a reference for any additional HAdV-B14 outbreak in China and provide the basis for the development of adenovirus vaccines and molecular pathogen surveillance protocols in high-risk areas. |
| اللغة: | English |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006be52af89a45c52c8ac8fff420e6ceTest http://europepmc.org/articles/PMC3612040Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....006be52af89a45c52c8ac8fff420e6ce |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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