التفاصيل البيبلوغرافية
| العنوان: |
C. trachomatis pgp3 Antibody Prevalence in Young Women in England, 1993–2010. |
| المؤلفون: |
Horner, Paddy, Soldan, Kate, Vieira, Sueli M., Wills, Gillian S., Woodhall, Sarah C., Pebody, Richard, Nardone, Anthony, Stanford, Elaine, McClure, Myra O. |
| المصدر: |
PLoS ONE; Aug2013, Vol. 8 Issue 8, p1-7, 7p |
| مصطلحات موضوعية: |
CHLAMYDIA, IMMUNOGLOBULINS, DISEASE prevalence, YOUNG women, WOMEN, COMMUNICABLE diseases, PUBLIC health, SEXUALLY transmitted diseases |
| مصطلحات جغرافية: |
UNITED Kingdom |
| مستخلص: |
Seroepidemiology of chlamydia can offer study opportunities and insights into cumulative risk of exposure that may contribute to monitoring the frequency of, and control of, genital chlamydia–the most commonly diagnosed STI in England. We undertook retrospective anonymous population-based cross-sectional surveys using an indirect IgG ELISA for chlamydia Pgp3 antibody. Sera from 4,732 women aged 17–24 years were tested. Samples were taken at 3-yearly intervals between 1993 and 2002, a period during which other data suggest chlamydia transmission may have been increasing, and from each year between 2007 and 2010. Seroprevalence increased in 17–24 year olds over time between 1993 and 2002. Between 2007 and 2010, age-standardised seroprevalence among 17–24 year olds decreased from 20% (95% CI: 17–23) to 15% (95%CI 12–17) (p = 0.0001). The biggest drop was among 20 to 21 year olds, where seroprevalence decreased from 21% in 2007 to 9% in 2010 (p = 0.002). These seroprevalence data reflect some known features of the epidemiology of chlamydia infection, and show that exposure to antibody-inducing chlamydia infection has declined in recent years. This decline was concurrent with increasing rates of screening for asymptomatic chlamydia. Serology should be explored further as a tool for evaluation of chlamydia control, including chlamydia screening programmes. [ABSTRACT FROM AUTHOR] |
|
Copyright of PLoS ONE is the property of Public Library of Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder