المؤلفون: Guo, Yan, Andersen, Shaneda Warren, Shu, Xiao-Ou, Michailidou, Kyriaki, Bolla, Manjeet K., Wang, Qin, Garcia-Closas, Montserrat, Milne, Roger L., Schmidt, Marjanka K., Chang-Claude, Jenny, Dunning, Allison, Bojesen, Stig E., Ahsan, Habibul, Aittomäki, Kristiina, Andrulis, Irene L., Anton-Culver, Hoda, Arndt, Volker, Beckmann, Matthias W., Beeghly-Fadiel, Alicia, Benitez, Javier, Bogdanova, Natalia V., Bonanni, Bernardo, Borresen-Dale, Anne-Lise, Brand, Judith, Brauch, Hiltrud, Brenner, Hermann, Bruening, Thomas, Burwinkel, Barbara, Casey, Graham, Chenevix-Trench, Georgia, Couch, Fergus J., Cox, Angela, Cross, Simon S., Czene, Kamila, Devilee, Peter, Doerk, Thilo, Dumont, Martine, Fasching, Peter A., Figueroa, Jonine, Flesch-Janys, Dieter, Fletcher, Olivia, Flyger, Henrik, Fostira, Florentia, Gammon, Marilie, Giles, Graham G., Guenel, Pascal, Haiman, Christopher A., Hamann, Ute, Hooning, Maartje J., Hopper, John L., Jakubowska, Anna, Jasmine, Farzana, Jenkins, Mark, John, Esther M., Johnson, Nichola, Jones, Michael E., Kabisch, Maria, Kibriya, Muhammad, Knight, Julia A., Koppert, Linetta B., Kosma, Veli-Matti, Kristensen, Vessela, Le Marchand, Loic, Lee, Eunjung, Li, Jingmei, Lindblom, Annika, Luben, Robert, Lubinski, Jan, Malone, Kathi E., Mannermaa, Arto, Margolin, Sara, Marme, Frederik, McLean, Catriona, Meijers-Heijboer, Hanne, Meindl, Alfons, Neuhausen, Susan L., Nevanlinna, Heli, Neven, Patrick, Olson, Janet E., Perez, Jose I. A., Perkins, Barbara, Peterlongo, Paolo, Phillips, Kelly-Anne, Pylkas, Katri, Rudolph, Anja, Santella, Regina, Sawyer, Elinor J., Schmutzler, Rita K., Seynaeve, Caroline, Shah, Mitul, Shrubsole, Martha J., Southey, Melissa C., Swerdlow, Anthony J., Toland, Amanda E., Tomlinson, Ian, Torres, Diana, Truong, Therese, Ursin, Giske, Van Der Luijt, Rob B., Verhoef, Senno, Whittemore, Alice S., Winqvist, Robert, Zhao, Hui, Zhao, Shilin, Hall, Per, Simard, Jacques, Kraft, Peter, Pharoah, Paul, Hunter, David, Easton, Douglas F., Zheng, Wei

المساهمون: Medicum, Kristiina Aittomäki / Principal Investigator, Clinicum, Department of Medical and Clinical Genetics, Department of Obstetrics and Gynecology

مصطلحات موضوعية: GENOME-WIDE ASSOCIATION, HORMONE-RECEPTOR STATUS, GENOTYPE IMPUTATION, PROSPECTIVE COHORT, FAT DISTRIBUTION, RELATIVE WEIGHT, OBESITY, LOCI, SIZE, METAANALYSIS, 3122 Cancers, 3123 Gynaecology and paediatrics, 3142 Public health care science, environmental and occupational health, 3111 Biomedicine

وصف الملف: application/pdf

العلاقة: The work conducted for this project at Vanderbilt University is supported primarily by National Cancer Institute research grants (R37CA070867 and R25CA160056) and endowment funds for the Ingram Professorship and Anne Potter Wilson Chair. JF is a volunteer for the NCI in the Epidemiology and Biostatistics Program and has no role in funding decisions. A complete funding statement is available in the Supporting Information. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.; Guo , Y , Andersen , S W , Shu , X-O , Michailidou , K , Bolla , M K , Wang , Q , Garcia-Closas , M , Milne , R L , Schmidt , M K , Chang-Claude , J , Dunning , A , Bojesen , S E , Ahsan , H , Aittomäki , K , Andrulis , I L , Anton-Culver , H , Arndt , V , Beckmann , M W , Beeghly-Fadiel , A , Benitez , J , Bogdanova , N V , Bonanni , B , Borresen-Dale , A-L , Brand , J , Brauch , H , Brenner , H , Bruening , T , Burwinkel , B , Casey , G , Chenevix-Trench , G , Couch , F J , Cox , A , Cross , S S , Czene , K , Devilee , P , Doerk , T , Dumont , M , Fasching , P A , Figueroa , J , Flesch-Janys , D , Fletcher , O , Flyger , H , Fostira , F , Gammon , M , Giles , G G , Guenel , P , Haiman , C A , Hamann , U , Hooning , M J , Hopper , J L , Jakubowska , A , Jasmine , F , Jenkins , M , John , E M , Johnson , N , Jones , M E , Kabisch , M , Kibriya , M , Knight , J A , Koppert , L B , Kosma , V-M , Kristensen , V , Le Marchand , L , Lee , E , Li , J , Lindblom , A , Luben , R , Lubinski , J , Malone , K E , Mannermaa , A , Margolin , S , Marme , F , McLean , C , Meijers-Heijboer , H , Meindl , A , Neuhausen , S L , Nevanlinna , H , Neven , P , Olson , J E , Perez , J I A , Perkins , B , Peterlongo , P , Phillips , K-A , Pylkas , K , Rudolph , A , Santella , R , Sawyer , E J , Schmutzler , R K , Seynaeve , C , Shah , M , Shrubsole , M J , Southey , M C , Swerdlow , A J , Toland , A E , Tomlinson , I , Torres , D , Truong , T , Ursin , G , Van Der Luijt , R B , Verhoef , S , Whittemore , A S , Winqvist , R , Zhao , H , Zhao , S , Hall , P , Simard , J , Kraft , P , Pharoah , P , Hunter , D , Easton , D F & Zheng , W 2016 , ' Genetically Predicted Body Mass Index and Breast Cancer Risk : Mendelian Randomization Analyses of Data from 145,000 Women of European Descent ' , PLoS Medicine , vol. 13 , no. 8 , 1002105 . https://doi.org/10.1371/journal.pmed.1002105Test; 84988940556; 239c9c8d-ecb1-4e17-a658-48af494e5ba5; http://hdl.handle.net/10138/167921Test; 000383357400022

الإتاحة: http://hdl.handle.net/10138/167921Test

المؤلفون: Gaudet, Mia M., Kuchenbaecker, Karoline B., Vijai, Joseph, Klein, Robert J., Kirchhoff, Tomas, McGuffog, Lesley, Barrowdale, Daniel, Dunning, Alison M., Lee, Andrew, Dennis, Joe, Healey, Sue, Dicks, Ed, Soucy, Penny, Sinilnikova, Olgam., Pankratz, Vernon S., Wang, Xianshu, Eldridge, Ronald C., Tessier, Daniel C., Vincent, Daniel, Bacot, Francois, Hogervorst, Frans B. L., Peock, Susan, Stoppa-Lyonnet, Dominique, Peterlongo, Paolo, Schmutzler, Rita K., Nathanson, Katherine L., Piedmonte, Marion, Singer, Christian F., Thomassen, Mads, Hansen, Thomas V. O., Neuhausen, Susan L., Blanco, Ignacio, Greene, Mark H., Garber, Judith, Weitzel, Jeffrey N., Andrulis, Irene L., Goldgar, David E., D'Andrea, Emma, Caldes, Trinidad, Nevanlinna, Heli, Osorio, Ana, van Rensburg, Elizabeth J., Arason, Adalgeir, Rennert, Gad, van den Ouweland, Ans M. W., van der Hout, Annemarie H., Kets, Carolien M., Aalfs, Cora M., Wijnen, Juul T., Aittomaki, Kristiina, kConFab Investigators, Ontario Canc Genetics Network, HEBON, EMBRACE, GEMO Study Collaborators, GENICA Network

المساهمون: Department of Obstetrics and Gynecology, Clinicum, Department of Medical and Clinical Genetics

مصطلحات موضوعية: BRCA2 MUTATION CARRIERS, TRANSCRIPTION FACTOR AP-2, GENOME-WIDE ASSOCIATION, COMMON VARIANTS, SUSCEPTIBILITY ALLELES, OVARIAN-CANCER, ZNF365, POPULATION, CONSORTIUM, SUBTYPES, 3111 Biomedicine

وصف الملف: application/pdf

العلاقة: Hospital grants, Cancer Fund of North Savo, the Finnish Cancer Organizations, the Academy of Finland, and by the strategic funding of the University of Eastern Finland. Kathleen Cuningham Consortium for Research into Familial Breast Cancer: kConFab is supported by grants from the National Breast Cancer Foundation and the National Health and Medical Research Council (NHMRC) and by the Queensland Cancer Fund; the Cancer Councils of New South Wales, Victoria, Tasmania, and South Australia; and the Cancer Foundation of Western Australia. G Chenevix-Trench and AB Spurdle are NHMRC Senior Research Fellows. Financial support for the AOCS was provided by the United States Army Medical Research and Materiel Command [DAMD17-01-1-0729], the Cancer Council of Tasmania and Cancer Foundation of Western Australia, and the NHMRC [199600]. G Chenevix-Trench is supported by the NHMRC. The Clinical Follow Up Study (funded 2001-2009 by NHMRC and currently by the National Breast Cancer Foundation and Cancer Australia #628333) Korean Hereditary Breast Cancer Study: KOHBRA is supported by a grant from the National R&D Program for Cancer Control, Ministry for Health, Welfare and Family Affairs, Republic of Korea (1020350). Leuven Multidisciplinary Breast Centre: LMBC is supported by the 'Stichting tegen Kanker' (232-2008 and 196-2010). D Lambrechts is supported by the FWO and the KULPFV/10/016-SymBioSysII. Mammary Carcinoma Risk Factor Investigation: The MARIE study was supported by the Deutsche Krebshilfe e.V. [70-2892-BR I], the Hamburg Cancer Society, the German Cancer Research Center, and the genotype work in part by the Federal Ministry of Education and Research (BMBF) Germany [01KH0402]. Mayo Clinic: MAYO is supported by NIH grant CA128978, an NCI Specialized Program of Research Excellence (SPORE) in Breast Cancer (CA116201), a U.S. Department of Defence Ovarian Cancer Idea award (W81XWH-10-1-0341), and grants from the Breast Cancer Research Foundation and the Komen Foundation for the Cure. Milan Breast Cancer Study Group: MBCSG was funded by grants from Fondazione Italiana per la Ricerca sul Cancro (Special Project "Hereditary tumors"), Italian Association for Cancer Research (AIRC, IG 8713), Italian Ministry of Health ("Progetto Tumori Femminili"), and by Italian citizens who allocated the 561000 share of their tax payment in support of the Fondazione IRCCS Istituto Nazionale Tumori, according to Italian laws (INT-Institutional strategic projects "5 x 1000"). Melbourne Collaborative Cohort Study: MCCS cohort recruitment was funded by VicHealth and Cancer Council Victoria. The MCCS was further supported by Australian NHMRC grants 209057, 251553 and 504711 and by infrastructure provided by Cancer Council Victoria. McGill University: The McGill Study was supported by Jewish General Hospital Weekend to End Breast Cancer, Quebec Ministry of Economic Development, Innovation and Export Trade. Multi-Ethnic Cohort: The MEC was supported by NIH grants CA63464, CA54281, CA098758, and CA132839. Memorial Sloan-Kettering Cancer Center: The MSKCC was supported by Breast Cancer Research Foundation, Niehaus Clinical Cancer Genetics Initiative, Andrew Sabin Family Foundation, and Lymphoma Foundation. Montreal Gene-Environment Breast Cancer Study: The work of MTLGEBCS was supported by the Quebec Breast Cancer Foundation, the Canadian Institutes of Health Research for the "CIHR Team in Familial Risks of Breast Cancer" program grant CRN-87521 and the Ministry of Economic Development, Innovation and Export Trade grant PSR-SIIRI-701.; Gaudet , M M , Kuchenbaecker , K B , Vijai , J , Klein , R J , Kirchhoff , T , McGuffog , L , Barrowdale , D , Dunning , A M , Lee , A , Dennis , J , Healey , S , Dicks , E , Soucy , P , Sinilnikova , O , Pankratz , V S , Wang , X , Eldridge , R C , Tessier , D C , Vincent , D , Bacot , F , Hogervorst , F B L , Peock , S , Stoppa-Lyonnet , D , Peterlongo , P , Schmutzler , R K , Nathanson , K L , Piedmonte , M , Singer , C F , Thomassen , M , Hansen , T V O , Neuhausen , S L , Blanco , I , Greene , M H , Garber , J , Weitzel , J N , Andrulis , I L , Goldgar , D E , D'Andrea , E , Caldes , T , Nevanlinna , H , Osorio , A , van Rensburg , E J , Arason , A , Rennert , G , van den Ouweland , A M W , van der Hout , A H , Kets , C M , Aalfs , C M , Wijnen , J T , Aittomaki , K , kConFab Investigators , Ontario Canc Genetics Network , HEBON , EMBRACE , GEMO Study Collaborators & GENICA Network 2013 , ' Identification of a BRCA2-Specific Modifier Locus at 6p24 Related to Breast Cancer Risk ' , PLoS Genetics , vol. 9 , no. 3 , e1003173 . https://doi.org/10.1371/journal.pgen.1003173Test; 84875733563; 91ce5844-414c-4066-abb5-692af80fef48; http://hdl.handle.net/10138/162509Test; 000316866700001

الإتاحة: http://hdl.handle.net/10138/162509Test

المؤلفون: Horne, Hisani N., Chung, Charles C., Zhang, Han, Yu, Kai, Prokunina-Olsson, Ludmila, Michailidou, Kyriaki, Bolla, Manjeet K., Wang, Qin, Dennis, Joe, Hopper, John L., Southey, Melissa C., Schmidt, Marjanka K., Broeks, Annegien, Muir, Kenneth, Lophatananon, Artitaya, Fasching, Peter A., Beckmann, Matthias W., Fletcher, Olivia, Johnson, Nichola, Sawyer, Elinor J., Tomlinson, Ian, Burwinkel, Barbara, Marme, Frederik, Guenel, Pascal, Truong, Therese, Bojesen, Stig E., Flyger, Henrik, Benitez, Javier, Gonzalez-Neira, Anna, Anton-Culver, Hoda, Neuhausen, Susan L., Brenner, Hermann, Arndt, Volker, Meindl, Alfons, Schmutzler, Rita K., Brauch, Hiltrud, Hamann, Ute, Nevanlinna, Heli, Khan, Sofia, Matsuo, Keitaro, Iwata, Hiroji, Dork, Thilo, Bogdanova, Natalia V., Lindblom, Annika, Margolin, Sara, Mannermaa, Arto, Kosma, Veli-Matti, Chenevix-Trench, Georgia, Wu, Anna H., den Berg, David Ven, kConFab-AOCS Investigators

المساهمون: Department of Obstetrics and Gynecology, Clinicum

مصطلحات موضوعية: GENOME-WIDE ASSOCIATION, COMMON VARIANTS, CONFER SUSCEPTIBILITY, GENETIC-VARIATION, 14Q24.1 RAD51L1, RISK, HETEROGENEITY, ALLELES, DISEASE, 3122 Cancers, 3123 Gynaecology and paediatrics

وصف الملف: application/pdf

العلاقة: Horne , H N , Chung , C C , Zhang , H , Yu , K , Prokunina-Olsson , L , Michailidou , K , Bolla , M K , Wang , Q , Dennis , J , Hopper , J L , Southey , M C , Schmidt , M K , Broeks , A , Muir , K , Lophatananon , A , Fasching , P A , Beckmann , M W , Fletcher , O , Johnson , N , Sawyer , E J , Tomlinson , I , Burwinkel , B , Marme , F , Guenel , P , Truong , T , Bojesen , S E , Flyger , H , Benitez , J , Gonzalez-Neira , A , Anton-Culver , H , Neuhausen , S L , Brenner , H , Arndt , V , Meindl , A , Schmutzler , R K , Brauch , H , Hamann , U , Nevanlinna , H , Khan , S , Matsuo , K , Iwata , H , Dork , T , Bogdanova , N V , Lindblom , A , Margolin , S , Mannermaa , A , Kosma , V-M , Chenevix-Trench , G , Wu , A H , den Berg , D V & kConFab-AOCS Investigators 2016 , ' Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus ' , PLoS One , vol. 11 , no. 8 , 0160316 . https://doi.org/10.1371/journal.pone.0160316Test; 84991088801; 3d90102c-62fb-4c3a-8257-683291838790; http://hdl.handle.net/10138/168116Test; 000382258100011

الإتاحة: http://hdl.handle.net/10138/168116Test

المؤلفون: Pelttari, Liisa M., Khan, Sofia, Vuorela, Mikko, Kiiski, Johanna I., Vilske, Sara, Nevanlinna, Viivi, Ranta, Salla, Schleutker, Johanna, Winqvist, Robert, Kallioniemi, Anne, Doerk, Thilo, Bogdanova, Natalia V., Figueroa, Jonine, Pharoah, Paul D. P., Schmidt, Marjanka K., Dunning, Alison M., Garcia-Closas, Montserrat, Bolla, Manjeet K., Dennis, Joe, Michailidou, Kyriaki, Wang, Qin, Hopper, John L., Southey, Melissa C., Rosenberg, Efraim H., Fasching, Peter A., Beckmann, Matthias W., Peto, Julian, dos-Santos-Silva, Isabel, Sawyer, Elinor J., Tomlinson, Ian, Burwinkel, Barbara, Surowy, Harald, Guenel, Pascal, Truong, Therese, Bojesen, Stig E., Nordestgaard, Borge G., Benitez, Javier, Gonzalez-Neira, Anna, Neuhausen, Susan L., Anton-Culver, Hoda, Brenner, Hermann, Arndt, Volker, Meindl, Alfons, Schmutzler, Rita K., Brauch, Hiltrud, Bruening, Thomas, Mattson, Johanna, Blomqvist, Carl, Aittomäki, Kristiina, Nevanlinna, Heli, kConFab-AOCS Investigators

المساهمون: Department of Obstetrics and Gynecology, Clinicum, Department of Oncology, Medicum, Kristiina Aittomäki / Principal Investigator, Department of Medical and Clinical Genetics, HUS Gynecology and Obstetrics

مصطلحات موضوعية: GENOME-WIDE ASSOCIATION, OVARIAN-CANCER, CONFER SUSCEPTIBILITY, GERMLINE MUTATIONS, 14Q24.1 RAD51L1, FANCONI-ANEMIA, RISK, GENE, VARIANTS, XRCC2, 3123 Gynaecology and paediatrics, 3122 Cancers

وصف الملف: application/pdf

العلاقة: The HEBCS was financially supported by the Helsinki University Hospital Research Fund, Academy of Finland (266528), the Finnish Cancer Society, The Nordic Cancer Union and the Sigrid Juselius Foundation. LMP received funding from Orion-Farmos Research Foundation, Maud Kuistila Memorial Foundation, Biomedicum Helsinki Foundation, Alfred Kordelin Foundation, Paulo Foundation and the Finnish Cultural Foundation. BCAC is funded by Cancer Research UK [C1287/A10118, C1287/A12014] and by the European Community's Seventh Framework Programme under grant agreement number 223175 (grant number HEALTH-F2-2009-223175) (COGS). Funding for the iCOGS infrastructure came from: the European Community's Seventh Framework Programme under grant agreement no 223175 (HEALTH-F2-2009223175) (COGS), Cancer Research UK (C1287/A10118, C1287/A 10710, C12292/A11174, C1281/A12014, C5047/A8384, C5047/A15007, C5047/A10692, C8197/A16565), the National Institutes of Health (CA128978) and Post-Cancer GWAS initiative (1U19 CA148537, 1U19 CA148065 and 1U19 CA148112 -the GAME-ON initiative), the Department of Defence (W81XWH-10-1-0341), the Canadian Institutes of Health Research (CIHR) for the CIHR Team in Familial Risks of Breast Cancer, Komen Foundation for the Cure, the Breast Cancer Research Foundation, and the Ovarian Cancer Research Fund. The Australian Breast Cancer Family Study (ABCFS) was supported by grant UM1 CA164920 from the National Cancer Institute (USA). The content of this manuscript does not necessarily reflect the views or policies of the National Cancer Institute or any of the collaborating centers in the Breast Cancer Family Registry (BCFR), nor does mention of trade names, commercial products, or organizations imply endorsement by the USA Government or the BCFR. The ABCFS was also supported by the National Health and Medical Research Council of Australia, the New South Wales Cancer Council, the Victorian Health Promotion Foundation (Australia) and the Victorian Breast Cancer Research Consortium. J.L.H. is a National Health and Medical Research Council (NHMRC) Australia Fellow and a Victorian Breast Cancer Research Consortium Group Leader. M.C.S. is a NHMRC Senior Research Fellow and a Victorian Breast Cancer Research Consortium Group Leader. The ABCS study was supported by the Dutch Cancer Society [grants NKI 2007-3839; 2009 4363]. The work of the BBCC was partly funded by ELAN-Fond of the University Hospital of Erlangen. The BBCS is funded by Cancer Research UK and Breakthrough Breast Cancer and acknowledges NHS funding to the NIHR Biomedical Research Centre, and the National Cancer Research Network (NCRN). ES is supported by NIHR Comprehensive Biomedical Research Centre, Guy's & St. Thomas' NHS Foundation Trust in partnership with King's College London, United Kingdom. IT is supported by the Oxford Biomedical Research Centre. The BSUCH study was supported by the Dietmar-Hopp Foundation, the Helmholtz Society and the German Cancer Research Center (DKFZ). The CECILE study was funded by Fondation de France, Institut National du Cancer (INCa), Ligue Nationale contre le Cancer, Ligue contre le Cancer Grand Ouest, Agence Nationale de Securite Sanitaire (ANSES), Agence Nationale de la Recherche (ANR). The CGPS was supported by the Chief Physician Johan Boserup and Lise Boserup Fund, the Danish Medical Research Council and Herlev Hospital.; Pelttari , L M , Khan , S , Vuorela , M , Kiiski , J I , Vilske , S , Nevanlinna , V , Ranta , S , Schleutker , J , Winqvist , R , Kallioniemi , A , Doerk , T , Bogdanova , N V , Figueroa , J , Pharoah , P D P , Schmidt , M K , Dunning , A M , Garcia-Closas , M , Bolla , M K , Dennis , J , Michailidou , K , Wang , Q , Hopper , J L , Southey , M C , Rosenberg , E H , Fasching , P A , Beckmann , M W , Peto , J , dos-Santos-Silva , I , Sawyer , E J , Tomlinson , I , Burwinkel , B , Surowy , H , Guenel , P , Truong , T , Bojesen , S E , Nordestgaard , B G , Benitez , J , Gonzalez-Neira , A , Neuhausen , S L , Anton-Culver , H , Brenner , H , Arndt , V , Meindl , A , Schmutzler , R K , Brauch , H , Bruening , T , Mattson , J , Blomqvist , C , Aittomäki , K , Nevanlinna , H & kConFab-AOCS Investigators 2016 , ' RAD51B in Familial Breast Cancer ' , PLoS One , vol. 11 , no. 5 , 0153788 . https://doi.org/10.1371/journal.pone.0153788Test; ORCID: /0000-0002-4089-7209/work/83053902; 85023753787; 5b69784b-a7c5-4168-b973-6460810ab7b9; http://hdl.handle.net/10138/163545Test; 000375676800015

الإتاحة: http://hdl.handle.net/10138/163545Test

المؤلفون: Blanco, Ignacio, Kuchenbaecker, Karoline, Cuadras, Daniel, Wang, Xianshu, Barrowdale, Daniel, Ruiz de Garibay, Gorka, Librado, Pablo, Sanchez-Gracia, Alejandro, Rozas, Julio, Bonifaci, Nuria, McGuffog, Lesley, Pankratz, Vernon S., Islam, Abul, Mateo, Francesca, Berenguer, Antoni, Petit, Anna, Catala, Isabel, Brunet, Joan, Feliubadalo, Lidia, Tornero, Eva, Benitez, Javier, Osorio, Ana, Cajal, Teresa Ramon Y., Nevanlinna, Heli, Aittomaki, Kristiina, Arun, Banu K., Toland, Amanda E., Karlan, Beth Y., Walsh, Christine, Lester, Jenny, Greene, Mark H., Mai, Phuong L., Nussbaum, Robert L., Andrulis, Irene L., Domchek, Susan M., Nathanson, Katherine L., Rebbeck, Timothy R., Barkardottir, Rosa B., Jakubowska, Anna, Lubinski, Jan, Durda, Katarzyna, Jaworska-Bieniek, Katarzyna, Claes, Kathleen, Van Maerken, Tom, Diez, Orland, Hansen, Thomas V., Jonson, Lars, Gerdes, Anne-Marie, Ejlertsen, Bent, de la Hoya, Miguel, Caldes, Trinidad, Dunning, Alison M., Oliver, Clare, Fineberg, Elena, Cook, Margaret, Peock, Susan, McCann, Emma, Murray, Alex, Jacobs, Chris, Pichert, Gabriella, Lalloo, Fiona, Chu, Carol, Dorkins, Huw, Paterson, Joan, Ong, Kai-Ren, Teixeira, Manuel R., Teixeira, Hogervorst, Frans B. L., van der Hout, Annemarie H., Seynaeve, Caroline, van der Luijt, Rob B., Ligtenberg, Marjolijn J. L., Devilee, Peter, Wijnen, Juul T., Rookus, Matti A., Meijers-Heijboer, Hanne E. J., Blok, Marinus J., van den Ouweland, Ans M. W., Aalfs, Cora M., Rodriguez, Gustavo C., Phillips, Kelly-Anne A., Piedmonte, Marion, Nerenstone, Stacy R., Bae-Jump, Victoria L., O'Malley, David M., Ratner, Elena S., Schmutzler, Rita K., Wappenschmidt, Barbara, Rhiem, Kerstin, Engel, Christoph, Meindl, Alfons, Ditsch, Nina, Arnold, Norbert, Plendl, Hansjoerg J., Niederacher, Dieter, Sutter, Christian, Wang-Gohrke, Shan, Steinemann, Doris, Preisler-Adams, Sabine, Kast, Karin, Varon-Mateeva, Raymonda, Gehrig, Andrea, Bojesen, Anders, Pedersen, Inge Sokilde, Sunde, Lone, Jensen, Uffe Birk, Thomassen, Mads, Kruse, Torben A., Foretova, Lenka, Peterlongo, Paolo, Bernard, Loris, Peissel, Bernard, Scuvera, Giulietta, Manoukian, Siranoush, Radice, Paolo, Ottini, Laura, Montagna, Marco, Agata, Simona, Maugard, Christine, Simard, Jacques, Soucy, Penny, Berger, Andreas, Fink-Retter, Anneliese, Singer, Christian F., Rappaport, Christine, Geschwantler-Kaulich, Daphne, Tea, Muy-Kheng, Pfeiler, Georg, John, Esther M., Miron, Alex, Neuhausen, Susan L., Terry, Mary Beth, Chung, Wendy K., Daly, Mary B., Goldgar, David E., Janavicius, Ramunas, Dorfling, Cecilia M., van Rensburg, Elisabeth J., Fostira, Florentia, Konstantopoulou, Irene, Garber, Judy, Godwin, Andrew K., Olah, Edith, Narod, Steven A., Rennert, Gad, Paluch, Shani Shimon, Laitman, Yael, Friedman, Eitan, Liljegren, Annelie, Rantala, Johanna, Stenmark-Askmalm, Marie, Loman, Niklas, Imyanitov, Evgeny N., Hamann, Ute, Spurdle, Amanda B., Healey, Sue, Weitzel, Jeffrey N., Herzog, Josef, Margileth, David, Gorrini, Chiara, Esteller, Manel, Gomez, Antonio, Sayols, Sergi, Vidal, Enrique, Heyn, Holger, Stoppa-Lyonnet, Dominique, Leone, Melanie, Barjhoux, Laure, Fassy-Colcombet, Marion, de Pauw, Antoine, Lasset, Christine, Ferrer, Sandra Fert, Castera, Laurent, Berthet, Pascaline, Cornelis, Francois, Bignon, Yves-Jean, Damiola, Francesca, Mazoyer, Sylvie, Sinilnikova, Olga M., Maxwell, Christopher A., Vijai, Joseph, Robson, Mark, Kauff, Noah, Corines, Marina J., Villano, Danylko, Cunningham, Julie, Lee, Adam, Lindor, Noralane, Lazaro, Conxi, Easton, Douglas F., Offit, Kenneth, Chenevix-Trench, Georgia, Couch, Fergus J., Antoniou, Antonis C., Angel Pujana, Miguel, BCFR, SWE-BRCA, kConFab Investigators, GEMO

المساهمون: Department of Obstetrics and Gynecology, Clinicum, Medicum, Haartman Institute (-2014), Department of Medical and Clinical Genetics

مصطلحات موضوعية: GENETIC INTERACTION NETWORKS, GENOME-WIDE ASSOCIATION, EXPRESSION SIGNATURE, SUSCEPTIBILITY LOCI, CHIP-SEQ, CELL, POLYMORPHISM, MODIFIERS, SURVIVAL, ELEMENTS, 3111 Biomedicine, 3122 Cancers, 3123 Gynaecology and paediatrics

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العلاقة: BCFR-all. This work was supported by grant UM1 CA164920 from the National Cancer Institute. The content of this manuscript does not necessarily reflect the views or policies of the National Cancer Institute or any of the collaborating centers in the Breast Cancer Family Registry (BCFR), nor does mention of trade names, commercial products, or organizations imply endorsement by the United States Government or the BCFR. BFBOCC: BFBOCC is supported by: Lithuania (BFBOCC-LT): Research Council of Lithuania grant LIG-07/2012 and Hereditary Cancer Association (Paveldimo vezio asociacija); Latvia (BFBOCC-LV) is partly supported by LSC grant 10.0010.08 and in part by a grant from the ESF Nr. 2009/0220/1DP/1.1.1.2.0/09/APIA/VIAA/016 and Liepaja's municipal council. BMBSA: BRCA-gene mutations and breast cancer in South African women (BMBSA) was supported by grants from the Cancer Association of South Africa (CANSA) to EJR. BRICOH: SLN was partially supported by the Morris and Horowitz Familes Endowed Professorship. CBCS: This work was supported by the NEYE Foundation. CNIO: This work was partially supported by Spanish Association against Cancer (AECC08), RTICC 06/0020/1060, FISPI08/1120, Mutua Madrilena Foundation (FMMA) and SAF2010-20493. COH-CCGCRN: City of Hope Clinical Cancer Genetics Community Network and the Hereditary Cancer Research Registry, supported in part by Award Number RC4CA153828 (PI: JW) from the National Cancer Institute and the Office of the Director, National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. CONSIT TEAM: Funds from Italian citizens who allocated the 5x1000 share of their tax payment in support of the Fondazione IRCCS Istituto Nazionale Tumori, according to Italian laws (INT-Institutional strategic projects '5x1000') to SM. Italian Association for Cancer Research (AIRC) to LO. CORE: The CIMBA data management and data analysis were supported by Cancer Research-United Kingdom grants C12292/A11174 and C1287/A10118. SH is supported by an NHMRC Program Grant to GCT. ACA is a Cancer Research -United Kingdom Senior Cancer Research Fellow. GCT is an NHMRC Senior Principal Research Fellow. DKFZ: The DKFZ study was supported by the DKFZ. DEMOKRITOS: This research has been co-financed by the European Union (European Social Fund-ESF) and Greek national funds through the Operational Program "Education and Lifelong Learning" of the National Strategic Reference Framework (NSRF)-Research Funding Program of the General Secretariat for Research & Technology: ARISTEIA. Investing in knowledge society through the European Social Fund. EMBRACE: EMBRACE is supported by Cancer Research United Kingdom Grants C1287/A10118 and C1287/A11990. DGE and FL are supported by an National Institute of Health Research (NIHR) grant to the Biomedical Research Centre, Manchester. The Investigators at The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust are supported by an NIHR grant to the Biomedical Research Centre at The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust. RE and EB are supported by Cancer Research United Kingdom Grant C5047/A8385. FCCC: The authors acknowledge support from The University of Kansas Cancer Center (P30 CA168524) and the Kansas Bioscience Authority Eminent Scholar Program. AKG was funded by 5U01CA113916, R01CA140323, and by the Chancellors Distinguished Chair in Biomedical Sciences Professorship.; Blanco , I , Kuchenbaecker , K , Cuadras , D , Wang , X , Barrowdale , D , Ruiz de Garibay , G , Librado , P , Sanchez-Gracia , A , Rozas , J , Bonifaci , N , McGuffog , L , Pankratz , V S , Islam , A , Mateo , F , Berenguer , A , Petit , A , Catala , I , Brunet , J , Feliubadalo , L , Tornero , E , Benitez , J , Osorio , A , Cajal , T R Y , Nevanlinna , H , Aittomaki , K , Arun , B K , Toland , A E , Karlan , B Y , Walsh , C , Lester , J , Greene , M H , Mai , P L , Nussbaum , R L , Andrulis , I L , Domchek , S M , Nathanson , K L , Rebbeck , T R , Barkardottir , R B , Jakubowska , A , Lubinski , J , Durda , K , Jaworska-Bieniek , K , Claes , K , Van Maerken , T , Diez , O , Hansen , T V , Jonson , L , Gerdes , A-M , Ejlertsen , B , de la Hoya , M , Caldes , T , Dunning , A M , Oliver , C , Fineberg , E , Cook , M , Peock , S , McCann , E , Murray , A , Jacobs , C , Pichert , G , Lalloo , F , Chu , C , Dorkins , H , Paterson , J , Ong , K-R , Teixeira , M R , Teixeira , Hogervorst , F B L , van der Hout , A H , Seynaeve , C , van der Luijt , R B , Ligtenberg , M J L , Devilee , P , Wijnen , J T , Rookus , M A , Meijers-Heijboer , H E J , Blok , M J , van den Ouweland , A M W , Aalfs , C M , Rodriguez , G C , Phillips , K-A A , Piedmonte , M , Nerenstone , S R , Bae-Jump , V L , O'Malley , D M , Ratner , E S , Schmutzler , R K , Wappenschmidt , B , Rhiem , K , Engel , C , Meindl , A , Ditsch , N , Arnold , N , Plendl , H J , Niederacher , D , Sutter , C , Wang-Gohrke , S , Steinemann , D , Preisler-Adams , S , Kast , K , Varon-Mateeva , R , Gehrig , A , Bojesen , A , Pedersen , I S , Sunde , L , Jensen , U B , Thomassen , M , Kruse , T A , Foretova , L , Peterlongo , P , Bernard , L , Peissel , B , Scuvera , G , Manoukian , S , Radice , P , Ottini , L , Montagna , M , Agata , S , Maugard , C , Simard , J , Soucy , P , Berger , A , Fink-Retter , A , Singer , C F , Rappaport , C , Geschwantler-Kaulich , D , Tea , M-K , Pfeiler , G , John , E M , Miron , A , Neuhausen , S L , Terry , M B , Chung , W K , Daly , M B , Goldgar , D E , Janavicius , R , Dorfling , C M , van Rensburg , E J , Fostira , F , Konstantopoulou , I , Garber , J , Godwin , A K , Olah , E , Narod , S A , Rennert , G , Paluch , S S , Laitman , Y , Friedman , E , Liljegren , A , Rantala , J , Stenmark-Askmalm , M , Loman , N , Imyanitov , E N , Hamann , U , Spurdle , A B , Healey , S , Weitzel , J N , Herzog , J , Margileth , D , Gorrini , C , Esteller , M , Gomez , A , Sayols , S , Vidal , E , Heyn , H , Stoppa-Lyonnet , D , Leone , M , Barjhoux , L , Fassy-Colcombet , M , de Pauw , A , Lasset , C , Ferrer , S F , Castera , L , Berthet , P , Cornelis , F , Bignon , Y-J , Damiola , F , Mazoyer , S , Sinilnikova , O M , Maxwell , C A , Vijai , J , Robson , M , Kauff , N , Corines , M J , Villano , D , Cunningham , J , Lee , A , Lindor , N , Lazaro , C , Easton , D F , Offit , K , Chenevix-Trench , G , Couch , F J , Antoniou , A C , Angel Pujana , M , BCFR , SWE-BRCA , kConFab Investigators & GEMO 2015 , ' Assessing Associations between the AURKA-HMMR-TPX2-TUBG1 Functional Module and Breast Cancer Risk in BRCA1/2 Mutation Carriers ' , PLoS One , vol. 10 , no. 4 , 0120020 . https://doi.org/10.1371/journal.pone.0120020Test; 84927153607; 9b869606-22ee-46c2-b8c4-94a9c0a51ec9; http://hdl.handle.net/10138/157025Test; 000352135600019

الإتاحة: http://hdl.handle.net/10138/157025Test