The limited prognostic role of echocardiograms in short-term follow-up after acute decompensated heart failure: An analysis of the Korean Heart Failure (KorHF) Registry
| العنوان: | The limited prognostic role of echocardiograms in short-term follow-up after acute decompensated heart failure: An analysis of the Korean Heart Failure (KorHF) Registry |
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| المؤلفون: | Seongwoo Han, Byung Su Yoo, Kyu Hyung Ryu, Eun Seok Jeon, Shung Chull Chae, Sung Hea Kim, Myeong Chan Cho, Jae Joong Kim, Hyun-Joong Kim, Dong-Ju Choi |
| المصدر: | PLoS ONE PLoS ONE, Vol 12, Iss 12, p e0188938 (2017) |
| بيانات النشر: | Public Library of Science, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Male, Acute decompensated heart failure, Etiology, Pulmonology, lcsh:Medicine, Kaplan-Meier Estimate, 030204 cardiovascular system & hematology, Pathology and Laboratory Medicine, Ventricular Function, Left, Diagnostic Radiology, 0302 clinical medicine, Endocrinology, Diastole, Ultrasound Imaging, Chronic Kidney Disease, Medicine and Health Sciences, 030212 general & internal medicine, Myocardial infarction, Registries, lcsh:Science, Multidisciplinary, Ejection fraction, Radiology and Imaging, Hazard ratio, Atrial fibrillation, Middle Aged, Prognosis, Treatment Outcome, Echocardiography, Nephrology, Cardiology, Female, Research Article, medicine.medical_specialty, Patients, Imaging Techniques, Endocrine Disorders, Chronic Obstructive Pulmonary Disease, Research and Analysis Methods, Patient Readmission, 03 medical and health sciences, Diagnostic Medicine, Internal medicine, Republic of Korea, medicine, Diabetes Mellitus, Humans, Aged, Proportional Hazards Models, Heart Failure, Proportional hazards model, business.industry, lcsh:R, Stroke Volume, medicine.disease, Health Care, Heart failure, Metabolic Disorders, Multivariate Analysis, lcsh:Q, business, Kidney disease, Follow-Up Studies |
| الوصف: | Background The prognostic values of the left ventricular ejection fraction (LVEF) and end-diastolic dimension (LVEDD) have primarily been shown among patients with chronic heart failure (HF), with little representation of patients with acute HF (AHF). Therefore, we investigated the value of these echocardiographic parameters in predicting clinical outcomes among patients in the Korean Heart Failure (KorHF) Registry. Methods The KorHF Registry consists of 3,200 patients who were hospitalized with AHF from 2005 to 2009. The Kaplan-Meier method was used to estimate survival and readmission, and differences were assessed using the log-rank test. Predictors of survival were identified using univariate and multivariate Cox proportional hazards regression analyses. Results Echocardiograms from 2,910 of the 3,200 patients (90.9%) were evaluated. The median LVEF and LVEDD (37% and 56 mm, respectively) were used as cut-offs for the binary transformation of each parameter. The cumulative death-free survival rates for all patients did not significantly differ based on LVEF or LVEDD quartiles; however, an LVEF greater than the median was associated with a better prognosis in ischemic HF patients (log-rank test; p = 0.039). Among ischemic HF patients, LVEF (dichotomized) was a significant predictor of death in a Cox model after adjusting for a history of HF, age, systolic blood pressure (SBP), serum sodium, sex, diabetes mellitus (DM), chronic obstructive pulmonary disease (COPD), chronic kidney disease (CKD), acute myocardial infarction (AMI), atrial fibrillation (Af) and anemia (hazard ratio (HR) 1.475, 95% confidence interval (CI) 1.099–1.979, p = 0.010). The cumulative readmission-free survival rates significantly differed among ischemic HF patients only when based on LVEDD quartiles (log-rank test; p = 0.001). In multivariate Cox proportional hazards regression analyses, LVEDD (dichotomized) remained a significant variable only among patients with ischemic HF after adjusting for sex, age, AMI, DM, COPD, serum sodium, SBP, blood urea nitrogen (BUN) and anemia (HR 1.401, 95% CI 1.067–1.841, p = 0.015). Conclusions Among ischemic AHF patients in the KorHF Registry, LVEF is associated with mortality, whereas LVEDD is only associated with readmission in a binary transformed form. |
| اللغة: | English |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1f21d1eca9cd005faa7b240638667dTest http://europepmc.org/articles/PMC5736190Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....4a1f21d1eca9cd005faa7b240638667d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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