Cholecystolithiasis Is Associated with Clonorchis sinensis Infection
| العنوان: | Cholecystolithiasis Is Associated with Clonorchis sinensis Infection |
|---|---|
| المؤلفون: | Zhen-liang Luo, Tie Qiao, Pei-ming Zheng, Xiao-bing Luo, Rui-hong Ma |
| المصدر: | PLoS ONE PLoS ONE, Vol 7, Iss 8, p e42471 (2012) |
| بيانات النشر: | Public Library of Science, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Male, Pathology, Epidemiology, lcsh:Medicine, Gallstones, Polymerase Chain Reaction, Cholelithiasis, Spectroscopy, Fourier Transform Infrared, lcsh:Science, Multidisciplinary, Clonorchis sinensis, biology, Zoonotic Diseases, Middle Aged, medicine.anatomical_structure, Veterinary Diseases, embryonic structures, Clonorchiasis, Medicine, Female, Biliary Disorders, Research Article, Adult, medicine.medical_specialty, China, Gastroenterology and Hepatology, Gallbladder Stone, Microbiology, Infectious Disease Epidemiology, Pigment stone, medicine, Animals, Humans, Biology, Fluorescent Dyes, Population Biology, Fluorescent pcr, Gallbladder, lcsh:R, Cholecystolithiasis, medicine.disease, biology.organism_classification, Trematodosis, Microscopy, Electron, Scanning, lcsh:Q, Parasitology, Veterinary Science, Zoology |
| الوصف: | Background The objective of this study was to analyze gallbladder stones for direct evidence of a relationship between Clonorchis sinensis infection and gallbladder stones formation. Methodology We investigated one hundred eighty-three gallbladder stones for the presence of Clonorchis sinensis eggs using microscopy, and analyzed their composition using Fourier transform infrared spectroscopy. We confirmed the presence of Clonorchis sinensis eggs in the gallbladder stones using real-time fluorescent PCR and scanning electron microscopy. Principal Findings Clonorchis sinensis eggs were detected in 122 of 183 gallbladder stones based on morphologic characteristics and results from real-time fluorescent PCR. The proportion of pigment stones, cholesterol stones and mixed gallstones in the egg-positive stones was 79.5% (97/122), 3.3% (4/122) and 17.2% (21/122), respectively, while 29.5% (18/61), 31.1% (19/61) and 39.3% (24/61) in the egg-negative stones. The proportion of pigment stone in the Clonorchis sinensis egg-positive stones was higher than in egg-negative stones (P |
| اللغة: | English |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea85f0fef16ec77bc8af48bff6be3e7Test http://europepmc.org/articles/PMC3414519Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....bea85f0fef16ec77bc8af48bff6be3e7 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
|---|