The Gut Microbiota of Wild Mice
| العنوان: | The Gut Microbiota of Wild Mice |
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| المؤلفون: | Eleanor M. Riley, Mark Viney, Stephen Abolins, Christian Bourne, Laura Weldon, Luca Lenzi |
| المصدر: | Weldon, L, Abolins, S, Lenzi, L, Bourne, C, Riley, E M & Viney, M 2015, ' The Gut Microbiota of Wild Mice ', PLoS ONE, vol. 10, no. 8, pp. e0134643 . https://doi.org/10.1371/journal.pone.0134643Test Weldon, L, Abolins, S, Lenzi, L, Bourne, C, Riley, E M & Viney, M 2015, ' The Gut Microbiota of Wild Mice ', PLoS ONE, vol. 10, no. 8, e0134643 . https://doi.org/10.1371/journal.pone.0134643Test PLoS ONE, Vol 10, Iss 8, p e0134643 (2015) PLoS ONE |
| بيانات النشر: | Public Library of Science, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Leptin, Male, Nematoda, lcsh:Medicine, Gut flora, DNA, Bacterial/isolation & purification, Cecum, Mice, fluids and secretions, Bacteroidetes/isolation & purification, lcsh:Science, Phylogeny, 0303 health sciences, Mites, Multidisciplinary, biology, Geography, Intestines, medicine.anatomical_structure, England, Cecum/microbiology, Viruses, Female, Research Article, DNA, Bacterial, Firmicutes, Firmicutes/isolation & purification, Intestine, Large/microbiology, digestive system, Microbiology, Caecum, 03 medical and health sciences, medicine, Animals, Microbiome, Intestine, Large, 030304 developmental biology, 030306 microbiology, Host (biology), Bacteroidetes, lcsh:R, Body Weight, Computational Biology, biology.organism_classification, Intestines/microbiology, Gastrointestinal Microbiome, stomatognathic diseases, Nematode, Leptin/blood, Mice/microbiology, Microbial genetics, lcsh:Q |
| الوصف: | The gut microbiota profoundly affects the biology of its host. The composition of the microbiota is dynamic and is affected by both host genetic and many environmental effects. The gut microbiota of laboratory mice has been studied extensively, which has uncovered many of the effects that the microbiota can have. This work has also shown that the environments of different research institutions can affect the mouse microbiota. There has been relatively limited study of the microbiota of wild mice, but this has shown that it typically differs from that of laboratory mice (and that maintaining wild caught mice in the laboratory can quite quickly alter the microbiota). There is also inter-individual variation in the microbiota of wild mice, with this principally explained by geographical location. In this study we have characterised the gut (both the caecum and rectum) microbiota of wild caught Mus musculus domesticus at three UK sites and have investigated how the microbiota varies depending on host location and host characteristics. We find that the microbiota of these mice are generally consistent with those described from other wild mice. The rectal and caecal microbiotas of individual mice are generally more similar to each other, than they are to the microbiota of other individuals. We found significant differences in the diversity of the microbiotas among mice from different sample sites. There were significant correlations of microbiota diversity and body weight, a measure of age, body-mass index, serum concentration of leptin, and virus, nematode and mite infection. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34132a56065b47338ca9b80734c10fc7Test https://researchonline.lshtm.ac.uk/id/eprint/2267036/1/pone.0134643.pdfTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....34132a56065b47338ca9b80734c10fc7 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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