دورية أكاديمية
Baseline risk markers and visit-to-visit variability in relation to kidney outcomes - A post-hoc analysis of the PERL study.
| العنوان: | Baseline risk markers and visit-to-visit variability in relation to kidney outcomes - A post-hoc analysis of the PERL study. |
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| المؤلفون: | Rotbain Curovic, Viktor, Roy, Neil, Hansen, Tine W, Luiza Caramori, M, Cherney, David Z, De Boer, Ian H, Emanuele, Mary Ann, Hirsch, Irl B, Lingvay, Ildiko, Mcgill, Janet B, Polsky, Sarit, Pop-Busui, Rodica, Sigal, Ronald J, Tuttle, Katherine R, Umpierrez, Guillermo E, Wallia, Amisha, Rosas, Sylvia E, Rossing, Peter, Study Group, PERL |
| المصدر: | Articles, Abstracts, and Reports |
| بيانات النشر: | Providence St. Joseph Health Digital Commons |
| سنة النشر: | 2022 |
| المجموعة: | Providence St. Joseph Health Digital Commons |
| مصطلحات موضوعية: | washington, spokane, pmrc, Endocrinology, Diabetes, and Metabolism, Nephrology |
| الوصف: | BACKGROUND: Baseline risk variables and visit-to-visit variability (VV) of systolic blood pressure (SBP), HbA METHODS: Post-hoc analysis of a double-blind randomized placebo-controlled clinical trial investigating allopurinol's effect on iohexol-derived glomerular filtration rate (iGFR) in type 1 diabetes with elevated UA. Primary outcome was iGFR change over three years. Linear regression with backwards selection of baseline clinical variables was performed to identify an optimized model forecasting iGFR change. Furthermore, VVs of SBP, HbA RESULTS: 404 participants were included in the primary analyses. In the optimized baseline variable model, higher HbA CONCLUSIONS: We identified several risk markers for faster iGFR decline in a high-risk population with type 1 diabetes. While further research is needed, our results indicate possible new and clinically feasible measures to risk stratify for DKD in type 1 diabetes. |
| نوع الوثيقة: | text |
| اللغة: | unknown |
| العلاقة: | https://digitalcommons.psjhealth.org/publications/6595Test; https://pubmed.ncbi.nlm.nih.gov/36265753Test |
| الإتاحة: | https://digitalcommons.psjhealth.org/publications/6595Test https://pubmed.ncbi.nlm.nih.gov/36265753Test |
| رقم الانضمام: | edsbas.989A359 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |