التفاصيل البيبلوغرافية
| العنوان: |
Lean body weight versus total body weight for propofol dosing |
| المؤلفون: |
McLeay, Sarah, Morrish, Glynn, Kirkpatrick, Carl, Green, Bruce |
| بيانات النشر: |
Population Approach Group in Europe |
| سنة النشر: |
2008 |
| المجموعة: |
The University of Queensland: UQ eSpace |
| مصطلحات موضوعية: |
Propofol, Total Body Weight (TBW), Obesity, Lean Body Weight (LBW), Dosing, 1115 Pharmacology and Pharmaceutical Sciences |
| الوصف: |
Clinicians have observed longer awakening times for obese compared to normal-weight patients when propofol is dosed as per label guidelines on Total Body Weight (TBW). This may be explained by the non-linear relationship between TBW and CL described by Schuttler et al1. Lean Body Weight (LBW) has been reported to have a linear relationship with drug clearance and therefore should be a more appropriate size descriptor for dosing of drugs e.g. propofol. |
| نوع الوثيقة: |
conference object |
| اللغة: |
English |
| تدمد: |
1871-6032 |
| العلاقة: |
orcid:0000-0003-1875-7995 |
| الإتاحة: |
https://espace.library.uq.edu.au/view/UQ:196195Test |
| رقم الانضمام: |
edsbas.CAEE4F9 |
| قاعدة البيانات: |
BASE |
