Disclosure of HIV status and its impact on the loss in the follow-up of HIV-infected patients on potent anti-retroviral therapy programs ina (post-) conflict setting: A retrospective cohort study from Goma, Democratic Republic of Congo
| العنوان: | Disclosure of HIV status and its impact on the loss in the follow-up of HIV-infected patients on potent anti-retroviral therapy programs ina (post-) conflict setting: A retrospective cohort study from Goma, Democratic Republic of Congo |
|---|---|
| المؤلفون: | Espérance Kashala-Abotnes, Paulin B. Mutombo, Mapatano Mala Ali, François B. Lepira, Patou Masika Musumari, Thorkild Tylleskär, Pierre Akilimali, Patrick K. Kayembe |
| المصدر: | PLoS ONE PLoS ONE, Vol 12, Iss 2, p e0171407 (2017) |
| بيانات النشر: | PLOS, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Male, RNA viruses, Pediatrics, lcsh:Medicine, Social Sciences, HIV Infections, Pathology and Laboratory Medicine, Global Health, Biochemistry, Geographical Locations, 0302 clinical medicine, Immunodeficiency Viruses, Sociology, Antiretroviral Therapy, Highly Active, Global health, Medicine and Health Sciences, Public and Occupational Health, 030212 general & internal medicine, lcsh:Science, Multidisciplinary, Incidence (epidemiology), Incidence, Attendance, Middle Aged, Viral Load, Vaccination and Immunization, Medical Microbiology, Viral Pathogens, Cohort, Viruses, Democratic Republic of the Congo, Female, Pathogens, 0305 other medical science, Viral load, Research Article, Adult, medicine.medical_specialty, Patients, Immunology, Antiretroviral Therapy, Disclosure, Microbiology, Education, 03 medical and health sciences, Antiviral Therapy, Retroviruses, medicine, Humans, Hemoglobin, Lost to follow-up, Microbial Pathogens, Survival analysis, Educational Attainment, Retrospective Studies, Nutrition, 030505 public health, business.industry, lcsh:R, Lentivirus, Organisms, Biology and Life Sciences, HIV, Proteins, Retrospective cohort study, CD4 Lymphocyte Count, Health Care, People and Places, Africa, lcsh:Q, Lost to Follow-Up, Preventive Medicine, business, Demography, Follow-Up Studies |
| الوصف: | Background The study aimed to identify the impact of non-disclosure of HIV status on the loss to follow-up (LTFU) of patients receiving anti-retroviral therapy. Methodology A historic cohort of HIV patients from 2 major hospitals in Goma, Democratic Republic of Congo was followed from 2004 to 2012. LTFU was defined as not taking an ART refill for a period of 3 months or longer since the last attendance, and had not yet been classified as ‘dead’ or ‘transferred-out’. Kaplan-Meier plots were used to determine the probability of LTFU as a function of time as inclusive of the cohort. The log-rank test was used to compare survival curves based on determinants. Cox proportional hazard modeling was used to measure predictors of LTFU from the time of treatment induction until December 15th, 2012 (the end-point). Results The median follow-up time was 3.99 years (IQR = 2.33 to 5.59). Seventy percent of patients had shared their HIV status with others (95% CI: 66.3–73.1). The proportion of LTFU was 12% (95%CI: 9.6–14.4). Patients who did not share their HIV status (Adjusted HR 2.28, 95% CI 1.46–2.29), patients who did not live in the city of Goma (Adjusted HR 1.97, 95% CI 1.02–3.77), and those who attained secondary or higher education level (Adjusted HR 1.60, 95% CI 1.02–2.53) had a higher hazard of being LTFU. Conclusion This study shows the relationship between the non–disclosure HIV status and LTFU. Healthcare workers in similar settings should pay more attention to clients who have not disclosed their HIV status, and to those living far from health settings where they receive medication. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4cf5f36048aaff18b90e7550bc2659Test https://hdl.handle.net/1956/16284Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....1f4cf5f36048aaff18b90e7550bc2659 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |