دورية أكاديمية
Synthesis and structure of 2-substituted pyrene-derived scaffolds
| العنوان: | Synthesis and structure of 2-substituted pyrene-derived scaffolds |
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| المؤلفون: | Cabral, Lília, Henriques, Marta Sofia, Paixão, José António, Lurdes S. Cristiano, M. |
| بيانات النشر: | Pergamon-Elsevier Science |
| سنة النشر: | 2017 |
| المجموعة: | Universidade do Algarve: Sapienta |
| مصطلحات موضوعية: | Derivatives |
| الوصف: | Pyrenes bear a propensity to form fluorescent excimers, and thus this chromophore is often found in sensors and fluorescent probes. 2-FunctionaIized pyrenes are of particular interest, however the preparation of these scaffolds is not trivial, involving synthetic routes that require 4,5,9,10-tetrahydropyrene as a key intermediate. Herein, the development and optimization of routes for the synthesis of 2-functionalized pyrene-derived building blocks, with potential to be used as tags in the preparation of fluorescent probes, is described. Additionally, the crystal structures of ethyl 4,5,9,10-tetrahydro-2-pyrene-5-oxopentanoate and 2-acetyl-4,5,9,10-tetrahydropyrene revealed distinct conformations of the saturated tetrahydropyrene rings. (C) 2017 Elsevier Ltd. All rights reserved. ; FEDER [PTDC/QUI-BIQ/112943/2009, PTDC/MAR-BIO/4132/2014, UID/Multi/04326/2013, UID/FIS/04564/2016] ; Fundacao para a Ciencia e a Tecnologia (FCT), Portugal ; info:eu-repo/semantics/publishedVersion |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0040-4039 |
| العلاقة: | info:eu-repo/grantAgreement/FCT/3599-PPCDT/112943/PT; info:eu-repo/grantAgreement/FCT/5876/147257/PT; http://hdl.handle.net/10400.1/12923Test |
| DOI: | 10.1016/j.tetlet.2017.10.058 |
| الإتاحة: | https://doi.org/10.1016/j.tetlet.2017.10.058Test http://hdl.handle.net/10400.1/12923Test |
| حقوق: | restrictedAccess ; http://creativecommons.org/licenses/by-nc-nd/4.0Test/ |
| رقم الانضمام: | edsbas.83DFDB9B |
| قاعدة البيانات: | BASE |
| تدمد: | 00404039 |
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| DOI: | 10.1016/j.tetlet.2017.10.058 |