دورية أكاديمية
New azaspiracids in Amphidomataceae (Dinophyceae)
| العنوان: | New azaspiracids in Amphidomataceae (Dinophyceae) |
|---|---|
| المؤلفون: | Krock, Bernd, Tillmann, Urban, Voss, Daniela, Koch, Boris P., Salas, Rafael, Witt, Matthias, Potvin, Eric, Jeong, Hae Jin |
| المساهمون: | Jeong, Hae Jin |
| بيانات النشر: | Pergamon Press |
| سنة النشر: | 2021 |
| المجموعة: | Seoul National University: S-Space |
| مصطلحات موضوعية: | DINOFLAGELLATE GENUS AZADINIUM, TRAP MASS-SPECTROMETRY, MYTILUS-EDULIS, SHELLFISH, ANALOGS, MUSSELS, TOXINS, BIOSYNTHESIS, CONFIRMATION, POPORUM, Azaspiracids, Azadinium poporum, Amphidoma languida, LC-MS/MS, Phycotoxin |
| الوصف: | Azaspiracids (AZAs) are a group of lipophilic polyether toxins implicated in incidents of shellfish poisoning in humans, particularly in northern Europe, which are produced by the small marine dinoflagellate Azadinium spinosum. Other related species/strains of the Amphidomataceae have not been proven to date to contain any of the known azaspiracids. Closer analyses of these species/strains by triple quadrupole mass spectrometry in the precursor and product ion mode now revealed four new compounds with high similarity to azaspiracids, all of them with a characteristic rn/z 348 fragment but with absence of the m/z 362 fragment. These compounds were detected in three species/strains, i.e. in North Sea isolates of Azadinium poporum (molecular mass: 845.5 Da), in a Korean isolate which has been designated as A. cf. poporum (molecular mass: 857.5 Da) and in Amphidoma languida isolated from Bantry Bay, Ireland (molecular masses: 815.5 and 829.5 Da). Cell quotas of roughly 2-20 fg per cell were in the same range as found for AZA-1/-2 in A. spinosum. Structures for all compounds were proposed by interpretation of fragmentation patterns and high resolution mass measurements using Fourier transform ion cyclotron resonance-mass spectrometry (FTICR-MS). (C) 2012 Elsevier Ltd. All rights reserved. ; N ; 1 |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| ردمك: | 978-0-00-308121-3 0-00-308121-4 |
| تدمد: | 0041-0101 |
| العلاقة: | Toxicon, Vol.60 No.5, pp.830-839; https://hdl.handle.net/10371/192724Test; 000308121400015; 2-s2.0-84863488452; 125874 |
| DOI: | 10.1016/j.toxicon.2012.05.007 |
| الإتاحة: | https://doi.org/10.1016/j.toxicon.2012.05.007Test https://hdl.handle.net/10371/192724Test |
| رقم الانضمام: | edsbas.DE849211 |
| قاعدة البيانات: | BASE |
| ردمك: | 9780003081213 0003081214 |
|---|---|
| تدمد: | 00410101 |
| DOI: | 10.1016/j.toxicon.2012.05.007 |