Descriptive analysis of esophageal cancer in Zambia using the cancer disease hospital database: young age, late stage at presentation
| العنوان: | Descriptive analysis of esophageal cancer in Zambia using the cancer disease hospital database: young age, late stage at presentation |
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| المؤلفون: | Jackson Chipaila, Nathaniel Chishinga, Lewis Banda, Akwi W. Asombang, Nancy Kasongo, Joao Filipe G. Montiero, John Muyutu |
| المصدر: | The Pan African Medical Journal Pan African Medical Journal; Vol. 39 No. 1 (2021) |
| بيانات النشر: | Pan African Medical Journal, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Adult, Male, Databases, Factual, Esophageal Neoplasms, Zambia, Adenocarcinoma, computer.software_genre, Endoscopy, Gastrointestinal, Young Adult, Age Distribution, medicine, Humans, esophageal cancer, Stage (cooking), Aged, Neoplasm Staging, Retrospective Studies, Cancer staging, Africa, Aged, 80 and over, Database, business.industry, Incidence, Research, Medical record, Incidence (epidemiology), Cancer, General Medicine, Middle Aged, Esophageal cancer, medicine.disease, Dysphagia, Female, Esophageal Squamous Cell Carcinoma, medicine.symptom, Deglutition Disorders, business, computer |
| الوصف: | Introduction:published data on oesophageal cancer (EC) in Zambia is limited and our study is the only study in Zambia evaluating the demographics and clinicopathologic features of patients presenting with EC at time of diagnosis. Methods:a retrospective analysis of data from Cancer Diseases Hospital (CDH) database was conducted on EC patients diagnosed between 2007 and December 2018. Medical records of EC patients were manually retrieved and reviewed using medical record numbers identified from the CDH database. Demographics, clinicopathologic features and modes of treatment were extracted. A coding sheet was created a priori, and data analysed in SAS version 9.3. Results:two hundred and seventy eight (278) complete EC medical records were included in the analysis, 183 (66%) were males, mean age was 55 years (range 21-89). One hundred and fifty six (156) (56%) resided in Lusaka, the location of CDH. The age-standardized incidence for EC was 5.5 per 100,000 people (95% CI, 4.3-6.6). The commonest symptom was dysphagia (83%), 97% were diagnosed endoscopically, squamous cell carcinoma and adenocarcinoma accounted for 90% and 8.3% respectively, 65% received treatment. One hundred and twenty four (124) medical records had missing cancer staging. Of 154 medical records with complete cancer staging, 98 (35%) were diagnosed at stage 4 of which 33% were between 40 and 49 years. Conclusion:the age-standardized incidence for EC is high at CDH. Patients with EC are predominantly male, reside in Lusaka and present with late stage EC at time of diagnosis; mostly between the ages of 40-49 years. Robust prospective research and improved data recording is needed. |
| وصف الملف: | application/pdf |
| تدمد: | 1937-8688 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddbcef797b9911be8450eb719bfca04dTest https://doi.org/10.11604/pamj.2021.39.12.23357Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....ddbcef797b9911be8450eb719bfca04d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19378688 |
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