Predictive value of isolated DLCO reduction in systemic sclerosis patients without cardio-pulmonary involvement at baseline
| العنوان: | Predictive value of isolated DLCO reduction in systemic sclerosis patients without cardio-pulmonary involvement at baseline |
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| المؤلفون: | Fabrizio Luppi, Marco Sebastiani, Andreina Teresa Manfredi, Stefania Cerri, Federica Lumetti, Dilia Giuggioli, Michele Colaci, Clodoveo Ferri |
| المساهمون: | Colaci, M, Giuggioli, D, Sebastiani, M, Manfredi, A, Lumetti, F, Luppi, F, Cerri, S, Ferri, C |
| المصدر: | Reumatismo, Vol 67, Iss 4, Pp 149-155 (2016) |
| بيانات النشر: | PAGEPress Publications, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | systemic sclerosis, Antibodie, DLCO, Lung fibrosis, Pulmonary arterial hypertension, Scleroderma, Systemic sclerosis, Rheumatology, lcsh:Medicine, Predictive Value of Test, Lung Disease, Severity of Illness Index, Systemic sclerosi, 0302 clinical medicine, Risk Factors, Diffusing capacity, Antinuclear, pulmonary arterial hypertension, Prospective Studies, 030212 general & internal medicine, Prospective cohort study, Respiratory Function Test, Carbon Monoxide, medicine.diagnostic_test, Interstitial lung disease, Pulmonary, Middle Aged, respiratory system, Prognosis, Autoantibodie, Respiratory Function Tests, medicine.anatomical_structure, Predictive value of tests, Antibodies, Antinuclear, Hypertension, Cardiology, Female, Human, Adult, medicine.medical_specialty, High-resolution computed tomography, lcsh:Internal medicine, Prognosi, Hypertension, Pulmonary, Lung fibrosi, Risk Assessment, Sensitivity and Specificity, Follow-Up Studie, 03 medical and health sciences, Predictive Value of Tests, Internal medicine, medicine, Humans, lcsh:RC31-1245, Autoantibodies, Aged, 030203 arthritis & rheumatology, Lung, Scleroderma, Systemic, business.industry, Risk Factor, Systemic, lcsh:R, Biomarker, medicine.disease, Pulmonary hypertension, Surgery, Prospective Studie, lung fibrosis, Pulmonary Diffusing Capacity, business, Interstitial, Lung Diseases, Interstitial, Biomarkers, Follow-Up Studies |
| الوصف: | Impaired diffusing capacity of the lung for carbon monoxide (DLCO) was frequently observed in systemic sclerosis (SSc) patients, generally related to the presence of interstitial lung disease (ILD) and/or pulmonary arterial hypertension (PAH). However, in clinical practice abnormally low DLCO values may be found also in the absence of these SSc complications. The objective was to investigate the prospective clinical relevance of isolated DLCO reduction at baseline in SSc patients. Ninety-seven SSc female patients (age at the diagnosis: 51.3±14.5 years; disease duration: 10.4±6.6 years; limited/diffuse skin subsets: 92/5), without any clinical, radiological (high resolution computed tomography), and echocardiographic manifestations of ILD or PAH at baseline, nor other lung or heart diseases able to affect DLCO, were recruited at our Rheumatology Centre. Patients with DLCO |
| اللغة: | English |
| تدمد: | 2240-2683 0048-7449 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d92321df3ecea2038c0639e96b5683bTest http://www.reumatismo.org/index.php/reuma/article/view/837Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....7d92321df3ecea2038c0639e96b5683b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22402683 00487449 |
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