التفاصيل البيبلوغرافية
| العنوان: |
FlexServ: an integrated tool for the analysis of protein flexibility. |
| المؤلفون: |
Jordi Camps, Oliver Carrillo, Agustí Emperador, Laura Orellana, Adam Hospital, Manuel Rueda, Damjan Cicin-Sain, Marco DAbramo, Josep Lluís Gelpí, Modesto Orozco |
| المصدر: |
Bioinformatics; Jul2009, Vol. 25 Issue 13, p1709-1709, 1p |
| مصطلحات موضوعية: |
COMPUTER software, PROTEINS, BIOINFORMATICS, STATISTICAL correlation, INFORMATION science, METHODOLOGY |
| مستخلص: |
Summary: FlexServ is a web-based tool for the analysis of protein flexibility. The server incorporates powerful protocols for the coarse-grained determination of protein dynamics using different versions of Normal Mode Analysis (NMA), Brownian dynamics (BD) and Discrete Dynamics (DMD). It can also analyze user provided trajectories. The server allows a complete analysis of flexibility using a large variety of metrics, including basic geometrical analysis, B-factors, essential dynamics, stiffness analysis, collectivity measures, Lindemanns indexes, residue correlation, chain-correlations, dynamic domain determination, hinge point detections, etc. Data is presented through a web interface as plain text, 2D and 3D graphics. Availability: http://mmb.pcb.ub.es/FlexServTest; http://www.inab.orgTest Contact: modesto@mmb.pcb.ub.es or gelpi@mmb.pcb.ub.es Supplementary information: Additional information and methodology details can be found at http://mmb.pcb.ub.es/FlexServ/helpTest. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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