التفاصيل البيبلوغرافية
| العنوان: |
The endogenous modulators of Ca2+–Mg2+-dependent ATPase in children with chronic kidney disease (CKD). |
| المؤلفون: |
Polak-Jonkisz, Dorota, Purzyc, Leszek, Laszki-Szcząchor, Krystyna, Musiał, Kinga, Zwolińnska, Danuta |
| المصدر: |
Nephrology Dialysis Transplantation; Feb2010, Vol. 25 Issue 2, p438-444, 7p, 1 Chart, 4 Graphs |
| مصطلحات موضوعية: |
KIDNEY diseases, CHRONIC diseases, JUVENILE diseases, ADENOSINE triphosphate, CALCIUM, HOMEOSTASIS |
| مستخلص: |
Background. Calcium homeostasis is disturbed in many ways in the course of chronic kidney disease (CKD). The concentration of free cytoplasmic calcium in erythrocytes is increased. Maintenance of a high concentration gradient (between the cystoplasmic and extracellular space) is possible only due to a finely tuned cooperation between many regulating systems in the cytoplasmic membranes and cell organelles. The aim of our study was to evaluate the activity of Ca2+–Mg2+-dependent ATPase (PMCA), calmodulin and calpain–calpastatin (CANP–CAST) system in erythrocytes of CKD children treated conservatively in the stages II–IV. [ABSTRACT FROM PUBLISHER] |
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| قاعدة البيانات: |
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