التفاصيل البيبلوغرافية
| العنوان: |
Association between non-alcoholic hepatic steatosis and hyper reactive blood pressure response on the exercise treadmill test. |
| المؤلفون: |
Laurinavicius, A. G., Bittencourt, M. S., Blaha, M. J., Nary, F. C., Kashiwagi, N. M., Conceiçao, R. D., Meneghelo, R. S., Prado, R. R., Carvalho, J. A. M., Nasir, K., Blumenthal, R. S., Santos, R. D. |
| المصدر: |
QJM: An International Journal of Medicine; Aug2016, Vol. 109 Issue 8, p531-537, 7p |
| مصطلحات موضوعية: |
HYPERTENSION, CARDIOVASCULAR disease diagnosis, CARDIOVASCULAR diseases risk factors, FATTY degeneration, BLOOD pressure, TREADMILLS, ULTRASONIC imaging |
| مستخلص: |
Aims: Non-alcoholic hepatic steatosis (HS) is associated with hypertension and increased cardiovascular risk. While Blood pressure hyper-reactive response (HRR) during peak exercise indicates an increased risk of incident hypertension and increased cardiovascular risk, no data on the association of non-alcoholic HS and HRR exists. In this study, we have evaluated the association of HS with HRR. Methods: We included 13 410 consecutive individuals with a mean age: 42.4 ± 8.9 years, 3561 (26.6%) female with normal resting blood pressure and without a previous diagnosis of hypertension, who underwent symptom limited exercise treadmill test, abdominal ultrasonography and clinical and laboratory evaluation. HS was detected by abdominal ultrasonography. HRR was defined by a peak exercise systolic blood pressure >220mmHg and/or elevation of 15mmHg or more in diastolic blood pressure from rest to peak exercise. Results: The prevalence of HS was 29.5% (n ¼ 3956). Overall, 4.6% (n = 619) of the study population presented a HRR. Subjects with HS had a higher prevalence of HRR (8.1 vs. 3.1%, odds ratio 2.8, 95% CI 2.4--3.3, P < 0.001). After adjustment for body mass index, waist circumference, fasting plasma glucose and low density lipoprotein cholesterol, HS (odds ratio 1.4, 95% CI 1.1-1.6, P = 0.002) remained independently associated with HRR. HS was additive to obesity markers in predicting exercise HRR. Conclusions: Non-alcoholic HS is independently associated with hyper-reactive exercise blood pressure response. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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