Surveillance study of candidemia in cancer patients in North China
| العنوان: | Surveillance study of candidemia in cancer patients in North China |
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| المؤلفون: | Peng Zhang, Wenfang Zhang, Zhe Liu, Zhenyi Ma, Ding Li, Shan Zheng |
| المصدر: | Medical Mycology. 51:378-384 |
| بيانات النشر: | Oxford University Press (OUP), 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | Adult, Azoles, Male, China, medicine.medical_specialty, Antifungal Agents, Microbial Sensitivity Tests, Metastasis, Risk Factors, Neoplasms, Amphotericin B, Internal medicine, Epidemiology, medicine, Humans, Risk factor, Candida albicans, Intensive care medicine, Aged, Candida, Demography, Retrospective Studies, Aged, 80 and over, Geography, biology, business.industry, Incidence, Incidence (epidemiology), Candidemia, Cancer, General Medicine, Middle Aged, biology.organism_classification, medicine.disease, Corpus albicans, Infectious Diseases, Female, business, medicine.drug |
| الوصف: | The surveillance and analysis of candidemia risk factors are necessary to reduce treatment failures in cancer patients. By understanding the geographic distribution of Candida spp. and their in vitro minimal antifungal inhibitory concentrations in cancer patients, optimal treatment protocols may be developed. On reviewing the candidemia data of cancer patients in Tianjin Medical University Cancer Institute and Hospital (TMUCIH), we found that the incidence rate was 0.34 – 0.53 cases per 1,000 admissions from 2008 – 2010, and the crude mortality was 31.7% during 2006 – 2010. Candida albicans was the most common species (48.8%), followed by C. parapsilosis (24.4%), C. glabrata (9.8%), C. tropicalis (9.8%), C. lusitaniae (4.9%), and C. famata (2.3%). All species were susceptible to azoles and showed low MICs to amphotericin B. Surgery was an independent risk factor in candidemia caused by C. albicans . Furthermore, among all cancer patients, those with digestive system neoplasms were most likely to develop candidemia. In addition, cancer patients with metastasis to distant organs were signifi cantly more prone to non- C. albicans Candida infection. This study provided data on the epidemiology of candidemia in cancer patients in North China which may be of value in such individuals with yeast infections. |
| تدمد: | 1460-2709 1369-3786 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4fd1d9ee2e298e7a9cb36469a538ed7Test https://doi.org/10.3109/13693786.2012.727481Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....a4fd1d9ee2e298e7a9cb36469a538ed7 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14602709 13693786 |
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