دورية أكاديمية

Echocardiographic predictors of reoperation for subaortic stenosis in children and adults

التفاصيل البيبلوغرافية
العنوان: Echocardiographic predictors of reoperation for subaortic stenosis in children and adults
المؤلفون: Theocharis, Paraskevi, Viola, Nicola, Papamichael, Nikolaos D, Kaarne, Markku, Bharucha, Tara
المصدر: European Journal of Cardio-Thoracic Surgery ; volume 56, issue 3, page 549-556 ; ISSN 1010-7940 1873-734X
بيانات النشر: Oxford University Press (OUP)
سنة النشر: 2019
مصطلحات موضوعية: Cardiology and Cardiovascular Medicine, Pulmonary and Respiratory Medicine, General Medicine, Surgery
الوصف: OBJECTIVES Subaortic stenosis (SAS) can present as various types of obstruction of the left ventricular outflow tract (LVOT) below the level of the aortic valve. Even though corrective surgery has been identified as the most effective treatment, SAS more frequently reoccurs requiring reoperation in a significant proportion of the patients. Previous studies have focused on predictors of recurrence in various subgroups of patients with SAS, but rarely in the overall population of patients with SAS. The aim of this study was to determine the predictors of recurrence of SAS after initial corrective surgery. METHODS Patients from the database of the Congenital Cardiology Department of the University Hospital of Southampton with significant SAS requiring corrective surgery were included in the study. Data retrieved were obtained and used to determine the predictors of SAS recurrence after the initial corrective surgery. RESULTS Eighty-two patients (paediatric, n = 72 and adult, n = 10) who underwent initial successful resection were included in the analysis. Thirty patients required reoperation for recurrent SAS. These were significantly younger (median age 3.0 vs 6.7 years, P = 0.002). The recurrence of SAS was more common in patients with an interrupted aortic arch (23.3% vs 3.8%, P = 0.010) and unfavourable left ventricle geometry (43.3% vs 7.6%, P < 0.001), with steeper aortoseptal angle (131.0° ± 8.7° vs 136.1° ± 8.6°, P = 0.030), shorter distance between the point of obstruction of the LVOT and the aortic valve annulus in systole and diastole (median 4.30 vs 5.90 mm, P = 0.003 and 3.65 vs 4.95 mm, P = 0.006, respectively) and in those who had higher residual peak and mean LVOT gradients postoperatively (29.3 ± 16.0 vs 19.8 ± 10.7 mmHg, P = 0.006 and 15.9 ± 8.3 vs 10.1 ± 5.8 mmHg, P = 0.002, respectively). Overall, the presence of an interrupted aortic arch [odds ratio (OR) 10.34, 95% confidence interval (CI) 1.46–73.25; P < 0.019] and unfavourable left ventricle geometry (OR 10.42, 95% CI ...
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1093/ejcts/ezz046
الإتاحة: https://doi.org/10.1093/ejcts/ezz046Test
http://academic.oup.com/ejcts/article-pdf/56/3/549/29191680/ezz046.pdfTest
حقوق: https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_modelTest
رقم الانضمام: edsbas.7EA9F21
قاعدة البيانات: BASE