دورية أكاديمية
European Renal Best Practice endorsement of guidelines for diagnosis and therapy of thrombotic thrombocytopaenic purpura published by the International Society on Thrombosis and Haemostasis
| العنوان: | European Renal Best Practice endorsement of guidelines for diagnosis and therapy of thrombotic thrombocytopaenic purpura published by the International Society on Thrombosis and Haemostasis |
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| المؤلفون: | Eller, Kathrin, Knoebl, Paul, Bakkaloglu, Sevcan A, Menne, Jan J, Brinkkoetter, Paul T, Grandt, Leonie, Thiem, Ursula, Coppo, Paul, Scully, Marie, Haller, Maria C |
| المساهمون: | Ablynx, Sanofi-Genzyme, Shire, Alexion, CSL Behring, Roche, Novo Nordisk, Sobi |
| المصدر: | Nephrology Dialysis Transplantation ; volume 37, issue 7, page 1229-1234 ; ISSN 0931-0509 1460-2385 |
| بيانات النشر: | Oxford University Press (OUP) |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Transplantation, Nephrology |
| الوصف: | Thrombotic thrombocytopenic purpura (TTP) is a life-threatening disease that is caused by severe ADAMTS-13 deficiency. Immune-mediated TTP develops due to autoantibodies against ADAMTS-13, whereas congenital TTP is caused by mutations in the ADAMTS13 gene. Diagnostic possibilities and treatment options in TTP have emerged in recent years, which prompted the International Society on Thrombosis and Haemostasis (ISTH) to publish clinical practice guidelines for the diagnosis and treatment of TTP in 2020. In this article, the European Renal Best Practice Working Group endorsed the ISTH guidelines and emphasizes a number of considerations, including the importance of rapid ADAMTS-13 activity testing, the use of rituximab and anti-von Willebrand factor therapies such as caplacizumab, that enhance the clinical applicability of the guidelines in Europe. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1093/ndt/gfac034 |
| DOI: | 10.1093/ndt/gfac034/43683261/gfac034.pdf |
| الإتاحة: | https://doi.org/10.1093/ndt/gfac034Test https://academic.oup.com/ndt/article-pdf/37/7/1229/44138417/gfac034.pdfTest |
| حقوق: | https://creativecommons.org/licenses/by-nc/4.0Test/ |
| رقم الانضمام: | edsbas.404339B2 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/ndt/gfac034 |
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