Longitudinal Evaluation of Language Impairment in Youth With Perinatally Acquired Human Immunodeficiency Virus (HIV) and Youth With Perinatal HIV Exposure
| العنوان: | Longitudinal Evaluation of Language Impairment in Youth With Perinatally Acquired Human Immunodeficiency Virus (HIV) and Youth With Perinatal HIV Exposure |
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| المؤلفون: | Mabel L. Rice, Tzy-Jyun Yao, Paige L. Williams, George K. Siberry, Sean M. Redmond, Murli Purswani, Jonathan S Russell, Howard J. Hoffman, Toni Frederick |
| المصدر: | Journal of the Pediatric Infectious Diseases Society. 5:S33-S40 |
| بيانات النشر: | Oxford University Press (OUP), 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Cart, Pediatrics, medicine.medical_specialty, Adolescent, Psychometrics, HIV Infections, Supplement Articles, Neuropsychological Tests, Standard score, Severity of Illness Index, 03 medical and health sciences, 0302 clinical medicine, Acquired immunodeficiency syndrome (AIDS), Risk Factors, 030225 pediatrics, Severity of illness, Humans, Medicine, Longitudinal Studies, 030212 general & internal medicine, Family history, Risk factor, Child, Language Disorders, business.industry, General Medicine, medicine.disease, Infectious Disease Transmission, Vertical, Infectious Diseases, Pediatrics, Perinatology and Child Health, Immunology, Female, business, Viral load, Cohort study |
| الوصف: | BACKGROUND Language impairment (LI) risk is increased for perinatally acquired human immunodeficiency virus-infected (PHIV) and perinatally exposed to HIV but uninfected (PHEU) youth. This study evaluates the persistence of LI in these groups. METHODS The Clinical Evaluation of Language Fundamentals was repeated on participants of the Pediatric HIV/AIDS Cohort Study Adolescent Master Protocol 18 months postbaseline. Regression models identified factors associated with change in standardized score (SC) and the resolution or development of LI. RESULTS Of 319 participants, 112 had LI at baseline. Upon re-evaluation, SCs were highly stable and changes were similar in PHIV (n = 212) and PHEU (n = 107) participants. Those with family history of language delays had a 2.39 point lower mean increase in SCs than those without, after controlling for demographic and socioeconomic factors and baseline LI status. Among PHIV participants, CD4 count |
| تدمد: | 2048-7207 2048-7193 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d06712298845dedd78caf2db6de479Test https://doi.org/10.1093/jpids/piw045Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....02d06712298845dedd78caf2db6de479 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20487207 20487193 |
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