Intestinal Metaplasia of the Esophagus or Esophagogastric Junction
| العنوان: | Intestinal Metaplasia of the Esophagus or Esophagogastric Junction |
|---|---|
| المؤلفون: | Guido N. J. Tytgat, Paul Drillenburg, Lonneke van Felius, Jelle Haringsma, Johanna W. van Sandick, Fiebo J.W. ten Kate, J. Jan B. van Lanschot, G. Johan A. Offerhaus, Wim Dekker |
| المساهمون: | Surgery, Extramural researchers, Pathology |
| المصدر: | American journal of clinical pathology, 117(1), 117-125. American Society of Clinical Pathologists |
| بيانات النشر: | Oxford University Press (OUP), 2002. |
| سنة النشر: | 2002 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Pathology, Esophageal Neoplasms, Adenocarcinoma, Biology, Gastroenterology, Barrett Esophagus, Intestinal mucosa, Risk Factors, Internal medicine, Metaplasia, Prevalence, medicine, Humans, Intestinal Mucosa, Esophagus, Antrum, Aged, Aged, 80 and over, Staining and Labeling, Esophageal disease, Mucins, Intestinal metaplasia, General Medicine, Middle Aged, medicine.disease, medicine.anatomical_structure, Barrett's esophagus, Esophagogastric Junction, medicine.symptom, Gastritis |
| الوصف: | Our purpose was to evaluate the clinical, histologic, and histochemical staining characteristics of intestinal metaplasia (IM) at an endoscopically normal-appearing esophagogastric junction (IM-EGJ) compared with IM in a columnar-lined esophagus (IM-CLE). A prospective study included 253 patients referred for elective upper gastrointestinal endoscopy. Biopsy specimens were obtained from 2 cm above and immediately distal to the squamocolumnar junction, the gastric corpus, and the antrum. Any red mucosa above the EGJ was sampled. IM-CLE (prevalence, 5.5%) typically occurred in white male smokers with a long history of reflux symptoms. IM-EGJ (prevalence, 9.1%) was associated with corpus and antrum gastritis and with IM at these sites. IM-CLE usually (13/14 [93%]) was the incomplete type IM, whereas only 12 (52%) of 23 patients in the IM-EGJ group had incomplete IM. IM-EGJ and IM-CLE should be considered as separate entities. Further research is needed to evaluate whether neoplastic progression of IM-EGJ is related to its mucin profile. |
| تدمد: | 1943-7722 0002-9173 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd2de1a010a897b2226278b5a22910bTest https://doi.org/10.1309/n15u-fn5r-3m5d-pe0uTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....bdd2de1a010a897b2226278b5a22910b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19437722 00029173 |
|---|