Hepatitis C Care Cascades for 3 Populations at High Risk: Low-income Trans Women, Young People Who Inject Drugs, and Men Who Have Sex With Men and Inject Drugs
| العنوان: | Hepatitis C Care Cascades for 3 Populations at High Risk: Low-income Trans Women, Young People Who Inject Drugs, and Men Who Have Sex With Men and Inject Drugs |
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| المؤلفون: | Shelley N. Facente, Peter Vickerman, Jennifer Hecht, Kimberly Page, Willi McFarland, Erin C. Wilson, Katie Burk, Hannah Fraser, Sheena Patel, Meghan D. Morris |
| المصدر: | et al. 2021, ' Hepatitis C Care Cascades for 3 Populations at High Risk : low-income trans women, young people who inject drugs, and men who have sex with men and inject drugs ', Clinical Infectious Diseases, vol. 73, no. 6, pp. e1290–e1295 . https://doi.org/10.1093/cid/ciab261Test Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol 73, iss 6 Clin Infect Dis |
| بيانات النشر: | Oxford University Press (OUP), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, HIV Infections, Hepacivirus, medicine.disease_cause, Medical and Health Sciences, Hepatitis, Men who have sex with men, Sexual and Gender Minorities, Substance Abuse, Intravenous, education.field_of_study, Liver Disease, Substance Abuse, virus diseases, Homosexuality, Hepatitis C, Biological Sciences, Infectious Diseases, Pharmaceutical Preparations, care cascade, Female, Intravenous, Infection, Adult, Microbiology (medical), Low income, transgender women, medicine.medical_specialty, Adolescent, Hepatitis C virus, Chronic Liver Disease and Cirrhosis, Population, Sexual and Gender Minorities (SGM/LGBT*), Microbiology, Unmet needs, Vaccine Related, Hepatitis - C, Internal medicine, Behavioral and Social Science, medicine, Humans, MSM, Homosexuality, Male, Online Only Articles, PWID, education, business.industry, Prevention, medicine.disease, Cross-Sectional Studies, Emerging Infectious Diseases, Good Health and Well Being, Virologic response, hepatitis C, Digestive Diseases, business, Limited resources |
| الوصف: | Background To achieve elimination of hepatitis C virus (HCV) infection, limited resources can be best allocated through estimation of “care cascades” among groups disproportionately affected. In San Francisco and elsewhere, these groups include young (age ≤ 30 years) people who inject drugs (YPWID), men who have sex with men who inject drugs (MSM-IDU), and low-income trans women. Methods We developed cross-sectional HCV care cascades for YPWID, MSM-IDU, and trans women using diverse data sources. Population sizes were estimated using an inverse variance-weighted average of estimates from the peer-reviewed literature between 2013 and 2019. Proportions of past/current HCV infection, diagnosed infection, treatment initiation, and evidence of cure (sustained virologic response at 12 weeks posttreatment) were estimated from the literature using data from 7 programs and studies in San Francisco between 2015 and 2020. Results The estimated number of YPWID in San Francisco was 3748; 58.4% had past/current HCV infection, of whom 66.4% were diagnosed with current infection, 9.1% had initiated treatment, and 50% had confirmed cure. The corresponding figures for the 8135 estimated MSM-IDU were: 29.4% with past/current HCV infection, 70.3% diagnosed with current infection, 28.4% initiated treatment, and 38.9% with confirmed cure. For the estimated 951 low-income trans women, 24.8% had past/current HCV infection, 68.9% were diagnosed with current infection, 56.5% initiated treatment, and 75.5% had confirmed cure. Conclusions In all 3 populations, diagnosis rates were relatively high; however, attention is needed to urgently increase treatment initiation in all groups, with a particular unmet need among YPWID. |
| وصف الملف: | application/pdf |
| تدمد: | 1537-6591 1058-4838 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4140bb31c44bf8ca09724b4f49e65c4bTest https://doi.org/10.1093/cid/ciab261Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....4140bb31c44bf8ca09724b4f49e65c4b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15376591 10584838 |
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