Pharmacists’ guide to the management of organ donors after brain death
| العنوان: | Pharmacists’ guide to the management of organ donors after brain death |
|---|---|
| المؤلفون: | Karen L. Hardinger, Jennifer L. Garber, Katelyn R. Richards, Jillian L. Descourouez, Catherine Korte |
| المصدر: | American Journal of Health-System Pharmacy. 73:1829-1839 |
| بيانات النشر: | Oxford University Press (OUP), 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Brain Death, medicine.medical_specialty, Resuscitation, Tissue and Organ Procurement, Organ Preservation Solutions, 030204 cardiovascular system & hematology, 030230 surgery, Pharmacists, Organ transplantation, 03 medical and health sciences, Professional Role, 0302 clinical medicine, Pharmacotherapy, medicine, Humans, Organ donation, Hormone replacement therapy, Intensive care medicine, Antihypertensive Agents, Pharmacology, business.industry, Health Policy, Organ preservation solution, Anticoagulants, Tissue Donors, Transplantation, Donation, business |
| الوصف: | Purpose This article reviews organ donor pathophysiology as it relates to medication use with the goal of maximizing the successful procurement and transplantation of donor organs. Summary The number of patients requiring organ transplantation continues to grow, yet organ donation rates remain flat, making it critical to appropriately manage each organ donor in order to ensure viability of all transplantable organs. The care given to one organ donor is tantamount to the care of several transplant recipients. Aggressive donor management ensures that the largest number of organs can be successfully procured and improves the organs’ overall quality. Hospital pharmacists are responsible for processing orders and preparing the medications outlined in donor management algorithms developed by their respective medical systems. It is important that pharmacists understand the details of the medications used in these protocols in order to critically evaluate each medication order and appropriately manage the donor. Typical medications used in organ donors after brain death include medications for blood pressure management and fluid resuscitation, medications necessary for electrolyte management, blood products, vasopressors, hormone replacement therapy, antiinfectives, anticoagulants, paralytics, and organ preservation solutions. Conclusion It is essential to provide optimal pharmacotherapy for each organ donor to ensure organ recovery and donation. Typical medications used in organ donors include agents for blood pressure management and fluid resuscitation, medications necessary for electrolyte management, blood products, vasopressors, hormone replacement therapy, antiinfectives, anticoagulants, paralytics, and organ preservation solutions. |
| تدمد: | 1535-2900 1079-2082 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56ae82f635a979185099b2aeea4c0be9Test https://doi.org/10.2146/ajhp150956Test |
| رقم الانضمام: | edsair.doi.dedup.....56ae82f635a979185099b2aeea4c0be9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15352900 10792082 |
|---|