المؤلفون: R. Ian Storer, Robert M. Owen, Emma Impey, Alex Gutteridge, Parul Choudhary, Caroline L. Benn, Magda Bictash, Paul J. Whiting

المصدر: Stem Cells Translational Medicine. 5:925-937

مصطلحات موضوعية: 0301 basic medicine, Cellular differentiation, Retinal Pigment Epithelium, Biology, Cell therapy, Macular Degeneration, 03 medical and health sciences, Re-Epithelialization, Transforming Growth Factor beta, Cyclic AMP, medicine, Humans, Enabling Technologies for Cell-Based Clinical Translation, Molecular Targeted Therapy, Cells, Cultured, Embryonic Stem Cells, Cell Proliferation, Retinal pigment epithelium, Cell Differentiation, Cell Biology, General Medicine, Anatomy, Transforming growth factor beta, Embryonic stem cell, eye diseases, Up-Regulation, Cell biology, Transplantation, 030104 developmental biology, medicine.anatomical_structure, Bucladesine, biology.protein, sense organs, Stem cell, Signal Transduction, Developmental Biology, Transforming growth factor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6849e06247da77ed9a0f131d1e956d29Test
https://doi.org/10.5966/sctm.2015-0247Test

المؤلفون: Sherry T. Hikita, Britney O Pennington, Zara Melkoumian, Dennis O. Clegg

المصدر: Pennington, BO; Clegg, DO; Melkoumian, ZK; & Hikita, ST. (2015). Defined culture of human embryonic stem cells and xeno-free derivation of retinal pigmented epithelial cells on a novel, synthetic substrate. Stem Cells Translational Medicine, 4(2), 165-177. doi: 10.5966/sctm.2014-0179. UC Santa Barbara: Retrieved from: http://www.escholarship.org/uc/item/5nk066gdTest
Stem cells translational medicine, vol 4, iss 2

مصطلحات موضوعية: Parylene-C, Cellular differentiation, Medical Biotechnology, Clinical Sciences, Immunocytochemistry, Cell Culture Techniques, Retinal Pigment Epithelium, Biology, Cell Line, Flow cytometry, Macular Degeneration, chemistry.chemical_compound, medicine, Humans, Protocols and Manufacturing for Cell-Based Therapies, Embryonic Stem Cells, Retina, Retinal pigment epithelium, medicine.diagnostic_test, Synthemax II-SC substrate, Age-related macular degeneration, Cell Differentiation, Epithelial Cells, Retinal, Cell Biology, General Medicine, Anatomy, Embryonic stem cell, eye diseases, Cell biology, medicine.anatomical_structure, chemistry, Cell culture, Human embryonic stem cells, Retinal pigmented epithelium, Biochemistry and Cell Biology, sense organs, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e7de3a8da3b789cb228650c3ccf3a5Test
https://doi.org/10.5966/sctm.2014-0179Test

المؤلفون: Peter J. Coffey, Amelia Lane, Amanda Carr, Lissa Rachel Philip, Matthew Smart, Ludmila Ruban, Chris Mason, Kate Fynes

المصدر: Stem Cells Translational Medicine. 3:1295-1304

مصطلحات موضوعية: Pluripotent Stem Cells, Cellular differentiation, Cell Culture Techniques, Retinal Pigment Epithelium, Biology, Cell Line, Cell therapy, Directed differentiation, Neural Stem Cells, medicine, Humans, Induced pluripotent stem cell, Homeodomain Proteins, Retinal pigment epithelium, Cell Differentiation, Cell Biology, General Medicine, Anatomy, Embryonic stem cell, eye diseases, Neural stem cell, Cell biology, Transplantation, medicine.anatomical_structure, sense organs, Transcription Factors, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13285a350fd835cc9734544075fe2331Test
https://doi.org/10.5966/sctm.2014-0094Test

المؤلفون: M. Joseph Phillips, Yingnan Yin, Wei Shen, Kyle Wallace, Enio T. Perez, Ruchira Singh, Xiaoqing Zhang, Elizabeth E. Capowski, Bikash R. Pattnaik, Molly A. Smith, Gerald A. Fishman, David Kuai, Patrick Halbach, Joseph M. Simonett, Jessica M. Martin, Lynda S. Wright, Xiangrong Guo, Amelia D. Verhoeven, David M. Gamm

المصدر: Human Molecular Genetics. 22:593-607

مصطلحات موضوعية: Induced Pluripotent Stem Cells, Context (language use), Retinal Pigment Epithelium, Vitelliform macular dystrophy, Protein degradation, Biology, medicine.disease_cause, Cell Line, Degenerative disease, Microscopy, Electron, Transmission, Phagocytosis, Chloride Channels, Genetics, medicine, Animals, Homeostasis, Humans, Immunoprecipitation, Macula Lutea, Bestrophins, Eye Proteins, Molecular Biology, Genetics (clinical), Calcium signaling, Retinal pigment epithelium, Cell Differentiation, Articles, General Medicine, Anatomy, Macular degeneration, Retinal Photoreceptor Cell Outer Segment, medicine.disease, Immunohistochemistry, eye diseases, Vitelliform Macular Dystrophy, Cell biology, Oxidative Stress, medicine.anatomical_structure, Gene Expression Regulation, Calcium, Cattle, sense organs, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54778a686cd4cf72d1416560f02f1f7bTest
https://doi.org/10.1093/hmg/dds469Test

المؤلفون: Judith A. West-Mays, Philip J. Gage, Trevor Williams, Sabine Fuhrmann, Erin A. Bassett, Amanda L. Zacharias

المصدر: Human Molecular Genetics. 19:1791-1804

مصطلحات موضوعية: genetic structures, Fluorescent Antibody Technique, Optic cup (anatomical), Biology, Polymerase Chain Reaction, Retina, Mice, Prosencephalon, In Situ Nick-End Labeling, Morphogenesis, Genetics, medicine, Animals, Hedgehog Proteins, Optic stalk, Eye Abnormalities, Molecular Biology, In Situ Hybridization, Genetics (clinical), DNA Primers, Mice, Knockout, Coloboma, Retinal pigment epithelium, Gene Expression Regulation, Developmental, Optic Nerve, Articles, General Medicine, Optic vesicle, Anatomy, medicine.disease, eye diseases, Cell biology, Disease Models, Animal, medicine.anatomical_structure, Transcription Factor AP-2, Eye development, Optic nerve, sense organs, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e629f24f29105d89100ed6d3833b2743Test
https://doi.org/10.1093/hmg/ddq060Test

المؤلفون: Brian Tulloch, Dafni Vlachantoni, Alan Lennon, Xinzhi Zhou, Alan F. Wright, Xinhua Shu, Caroline Hayward

المصدر: Human Molecular Genetics. 15:1680-1689

مصطلحات موضوعية: Retinal degeneration, Proteasome Endopeptidase Complex, Protein Folding, Pathology, medicine.medical_specialty, genetic structures, Degeneration (medical), Biology, Drusen, Endoplasmic Reticulum, Cell Line, Macular Degeneration, Mice, chemistry.chemical_compound, Cell Adhesion, Genetics, medicine, Animals, Humans, Age of Onset, Eye Proteins, Pigment Epithelium of Eye, Molecular Biology, Genetics (clinical), Retinal pigment epithelium, Membrane Proteins, Retinal, General Medicine, Anatomy, Macular degeneration, Macular dystrophy, medicine.disease, eye diseases, medicine.anatomical_structure, chemistry, Mutation, Maculopathy, Collagen, sense organs, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::874d3a7ba229a897dded77e86dffbce8Test
https://doi.org/10.1093/hmg/ddl091Test

المؤلفون: Juergen K Naggert, Minzhong Yu, Gayle B. Collin, Dirk Hubmacher, Suneel S. Apte, Patsy M. Nishina, Jeremy R. Charette, Mark P. Krebs, Neal S. Peachey, Wanda L. Hicks, Lisa Stone

المصدر: Human Molecular Genetics. :ddv399

مصطلحات موضوعية: Nonsense mutation, Retinal Pigment Epithelium, Biology, Gene mutation, medicine.disease_cause, Ectopia Lentis, Fibril-Associated Collagens, Mice, Pupil Disorders, Lens, Crystalline, Genetics, medicine, Animals, Humans, Ectopia lentis, Molecular Biology, Genetics (clinical), Mutation, Retinal pigment epithelium, ADAMTS, Homozygote, Cell Differentiation, Pupil, Articles, General Medicine, Anatomy, medicine.disease, Mice, Mutant Strains, eye diseases, Cell biology, ADAM Proteins, Axial Length, Eye, Disease Models, Animal, medicine.anatomical_structure, Gene Expression Regulation, Codon, Nonsense, Lens (anatomy), ADAMTS4 Protein, Collagen, sense organs, Procollagen N-Endopeptidase, Fibrillin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dee96f8b96ef6d3b5e725c310f5e89dTest
https://doi.org/10.1093/hmg/ddv399Test