دورية أكاديمية
Management of Behcet's syndrome
العنوان: | Management of Behcet's syndrome |
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المؤلفون: | Karadağ, Ömer, Bolek, Ertugrul Cagri |
المساهمون: | İç Hastalıkları |
بيانات النشر: | Oxford |
سنة النشر: | 2020 |
المجموعة: | Hacettepe University Institutional Repository |
مصطلحات موضوعية: | Behcet’s disease, Neurobehcet’s syndrome, biologic agents, interferon alpha, uveitis, Vascular Behcet’s syndrome, Tıp uygulaması |
الوصف: | Behcet's syndrome (BS) is a variable vessel vasculitis with heterogeneous clinical features. Skin, mucosa and joint involvement can cause impairment of quality of life but do not cause permanent damage whereas untreated eye, vascular, nervous system and gastrointestinal system involvement can cause serious damage and even death. Management of BS as a multidisciplinary team enables a faster and more accurate diagnosis and well-integrated treatment strategies. Corticosteroids are the mainstay of therapy. Colchicine, AZA, ciclosporin-A, cyclophosphamide, IFN alpha, and tumour necrosis factor alpha inhibitors are other agents used as induction and/or maintenance therapy. Although biologic agents have been increasingly used, there are still unmet needs. Head-to-head comparison studies of some therapeutic options (e.g. TNF inhibitors vs IFN alpha in uveitis) are required. Novel therapeutic agents in the pipeline could change the standard of care for BS in the future. |
نوع الوثيقة: | article in journal/newspaper |
وصف الملف: | application/pdf |
اللغة: | English |
العلاقة: | Rheumatology; Karadag O, Bolek EC. Management of Behcet's syndrome. Rheumatology (Oxford). 2020 May 1;59(Suppl 3):iii108-iii117. doi:10.1093/rheumatology/keaa086. PMID: 32348509.; https://doi.org/10.1093/rheumatology/keaa086Test; https://pubmed.ncbi.nlm.nih.gov/32348509Test/; https://academic.oup.com/rheumatology/article/59/Supplement_3/iii108/5826894Test; http://hdl.handle.net/11655/23567Test; 59; 108; 117 |
DOI: | 10.1093/rheumatology/keaa086 |
الإتاحة: | https://doi.org/10.1093/rheumatology/keaa086Test http://hdl.handle.net/11655/23567Test https://pubmed.ncbi.nlm.nih.gov/32348509Test/ https://academic.oup.com/rheumatology/article/59/Supplement_3/iii108/5826894Test |
حقوق: | info:eu-repo/semantics/openAccess ; http://creativecommons.org/publicdomain/zero/1.0Test/ |
رقم الانضمام: | edsbas.FF4B5693 |
قاعدة البيانات: | BASE |
DOI: | 10.1093/rheumatology/keaa086 |
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