دورية أكاديمية

Critically ill patients with COVID-19 with ECMO and artificial liver plasma exchange ; A retrospective study

التفاصيل البيبلوغرافية
العنوان: Critically ill patients with COVID-19 with ECMO and artificial liver plasma exchange ; A retrospective study
المؤلفون: Liu, Jian, Dong, Yong-Quan, Yin, Jie, He, Guojun, Wu, Xiaoxin, Li, Jianping, Qiu, Yunqing, He, Xuelin
المساهمون: Zhejiang Province Public Welfare Technology Application Research Project (CN), China
المصدر: Medicine ; volume 99, issue 26, page e21012 ; ISSN 0025-7974 1536-5964
بيانات النشر: Ovid Technologies (Wolters Kluwer Health)
سنة النشر: 2020
الوصف: COVID-19 is an emerging infectious disease capable of causing severe pneumonia. We aimed to characterize a group of critically ill patients in a single-center study. This was a retrospective case series of 23 patients with confirmed COVID-19-related critical illness in the intensive care unit (ICU) of a hospital in Hangzhou Zhejiang Province between January 22 and March 20, 2020. Of the 23 critically ill patients, the median age was 66 years (interquartile range [IQR] 59–80 years). The median time from disease onset to ICU admission was 10 days (IQR 6–11 days), to mechanical ventilation (MV) was 11 days (IQR 7.75–13 days), to artificial liver plasma exchange was 12 days (IQR 9.75–14.75 days), and to extracorporeal membrane oxygenation (ECMO) was 22 days (IQR 17.5–30 days). Nine patients required high flow oxygen. Fourteen patients received MV. Six required ECMO. Nine received artificial liver plasma exchange. Mortality was 0 at day 28. Mortality was 0 at day 28 in our single-center study. Extracorporeal membrane oxygenation reduced the requirements for ventilator support. Artificial liver plasma exchange significantly reduced inflammatory cytokine levels. These supportive therapies helped to extend the patients’ survival times and increase the chance of follow-up treatments.
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1097/md.0000000000021012
DOI: 10.1097/MD.0000000000021012
الإتاحة: https://doi.org/10.1097/md.0000000000021012Test
حقوق: http://creativecommons.org/licenses/by-nc/4.0Test
رقم الانضمام: edsbas.EA49372C
قاعدة البيانات: BASE