Improvements in Nutritional Management as a Determinant of Reduced Mortality From Community-Acquired Lower Respiratory Tract Infection in Hospitalized Children From Rural Central Africa
التفاصيل البيبلوغرافية
العنوان:
Improvements in Nutritional Management as a Determinant of Reduced Mortality From Community-Acquired Lower Respiratory Tract Infection in Hospitalized Children From Rural Central Africa
In-hospital mortality from lower respiratory tract infections (LTRI) is unacceptably high in developing countries where LTRI are still a leading cause of death. Objective: To identify new approaches to reduce in-hospital mortality of LRTI through the improvement of its management. The prospectively collected database of children admitted during an 11-year period with LRTI in a pediatric rural hospital in Central Africa was reviewed to determine the predictors of death and to evaluate the impact on mortality of 4 different protocols for the management of malnutrition. During the study period 859 children were admitted with a nonmeasles severe LRTI. In the 3-year period during which blood cultures were obtained 29.0% of the children with LRTI were bacteremic and multiresistant Enterobacteriaceae were recovered in 81.4% of positive blood cultures. Independent predictors of death in children without edema were age