Feasibility of Real-Time Magnetic Resonance Imaging for Catheter Guidance in Electrophysiology Studies
| العنوان: | Feasibility of Real-Time Magnetic Resonance Imaging for Catheter Guidance in Electrophysiology Studies |
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| المؤلفون: | Glenn Meininger, Ritsushi Kato, Aravindan Kolandaivelu, Albert C. Lardo, Saman Nazarian, Hugh Calkins, Ariel Roguin, David A. Bluemke, Robert C. Susil, Ronald D. Berger, Hiroshi Ashikaga, Timm L. Dickfeld, Menekhem M. Zviman, Henry R. Halperin |
| المصدر: | Circulation. 118:223-229 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2008. |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | Bundle of His, Cardiac Catheterization, medicine.medical_specialty, Hot Temperature, medicine.medical_treatment, Magnetic Resonance Imaging, Interventional, Article, Catheterization, Dogs, Computer Systems, Physiology (medical), medicine, Animals, Humans, Fluoroscopy, Heart Atria, Cardiac catheterization, medicine.diagnostic_test, Echo-Planar Imaging, business.industry, Cardiac Pacing, Artificial, Magnetic resonance imaging, Real-time magnetic resonance imaging, Electrophysiology, Catheter, medicine.anatomical_structure, Ventricle, Feasibility Studies, Radiology, Cardiology and Cardiovascular Medicine, business, Biomedical engineering |
| الوصف: | Background— Compared with fluoroscopy, the current imaging standard of care for guidance of electrophysiology procedures, magnetic resonance imaging (MRI) provides improved soft-tissue resolution and eliminates radiation exposure. However, because of inherent magnetic forces and electromagnetic interference, the MRI environment poses challenges for electrophysiology procedures. In this study, we sought to test the feasibility of performing electrophysiology studies with real-time MRI guidance. Methods and Results— An MRI-compatible electrophysiology system was developed. Catheters were targeted to the right atrium, His bundle, and right ventricle of 10 mongrel dogs (23 to 32 kg) via a 1.5-T MRI system using rapidly acquired fast gradient-echo images (≈5 frames per second). Catheters were successfully positioned at the right atrial, His bundle, and right ventricular target sites of all animals. Comprehensive electrophysiology studies with recording of intracardiac electrograms and atrial and ventricular pacing were performed. Postprocedural pathological evaluation revealed no evidence of thermal injury to the myocardium. After proof of safety in animal studies, limited real-time MRI-guided catheter mapping studies were performed in 2 patients. Adequate target catheter localization was confirmed via recording of intracardiac electrograms in both patients. Conclusions— To the best of our knowledge, this is the first study to report the feasibility of real-time MRI-guided electrophysiology procedures. This technique may eliminate patient and staff radiation exposure and improve real-time soft tissue resolution for procedural guidance. |
| تدمد: | 1524-4539 0009-7322 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd964da8c3747d01f205916de6989a9Test https://doi.org/10.1161/circulationaha.107.742452Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....dfd964da8c3747d01f205916de6989a9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15244539 00097322 |
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